T1 ρ and T2 mapping for the determination of articular cartilage denaturalization with osteonecrosis of the femoral head: A prospective controlled trial

2018 ◽  
Vol 49 (3) ◽  
pp. 760-767 ◽  
Author(s):  
Xiaorui Han ◽  
Guoju Hong ◽  
Leilei Chen ◽  
Man Zhao ◽  
Yuan Guo ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Femoral Head ◽  
T2 Mapping ◽  
Controlled Trial

Preoperative T2 mapping MRI of articular cartilage values predicts postoperative osteoarthritis progression following rotational acetabular osteotomy

2021 ◽  
Vol 103-B (9) ◽  
pp. 1472-1478
Author(s):  
Takeshi Shoji ◽  
Hideki Saka ◽  
Tadashi Inoue ◽  
Yuichi Kato ◽  
Yusuke Fujiwara ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Femoral Head ◽  
Early Stage ◽  
T2 Mapping ◽  
Joint Space Width ◽  
Preoperative Assessment ◽  
Joint Space ◽  
Mapping Technique ◽  
Rotational Acetabular Osteotomy ◽  
Characteristic Analysis

Aims Rotational acetabular osteotomy (RAO) has been reported to be effective in improving symptoms and preventing osteoarthritis (OA) progression in patients with mild to severe develomental dysplasia of the hip (DDH). However, some patients develop secondary OA even when the preoperative joint space is normal; determining who will progress to OA is difficult. We evaluated whether the preoperative cartilage condition may predict OA progression following surgery using T2 mapping MRI. Methods We reviewed 61 hips with early-stage OA in 61 patients who underwent RAO for DDH. They underwent preoperative and five-year postoperative radiological analysis of the hip. Those with a joint space narrowing of more than 1 mm were considered to have 'OA progression'. Preoperative assessment of articular cartilage was also performed using 3T MRI with the T2 mapping technique. The region of interest was defined as the weightbearing portion of the acetabulum and femoral head. Results There were 16 patients with postoperative OA progression. The T2 values of the centre to the anterolateral region of the acetabulum and femoral head in the OA progression cases were significantly higher than those in patients without OA progression. The preoperative T2 values in those regions were positively correlated with the narrowed joint space width. The receiver operating characteristic analysis revealed that the T2 value of the central portion in the acetabulum provided excellent discrimination, with OA progression patients having an area under the curve of 0.858. Furthermore, logistic regression analysis showed T2 values of the centre to the acetabulum’s anterolateral portion as independent predictors of subsequent OA progression (p < 0.001). Conclusion This was the first study to evaluate the relationship between intra-articular degeneration using T2 mapping MRI and postoperative OA progression. Our findings suggest that preoperative T2 values of the hip can be better prognostic factors for OA progression than radiological measures following RAO. Cite this article: Bone Joint J 2021;103-B(9):1472–1478.

scholarly journals Bi-Component T2 Mapping Correlates with Articular Cartilage Material Properties

2020 ◽  
pp. 110215
Author(s):  
Matthew M. Grondin ◽  
Fang Liu ◽  
Michael F. Vignos ◽  
Alexey Samsonov ◽  
Wan-Ju Li ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Material Properties ◽  
T2 Mapping

scholarly journals Bone Morphogenetic Protein in Scaphoid Nonunion: A Systematic Review

2021 ◽  
Author(s):  
Michael M. Polmear ◽  
Ashley B. Anderson ◽  
Paul J. Lanier ◽  
Justin D. Orr ◽  
Leon J. Nesti ◽  
...  
Keyword(s):  
Literature Review ◽  
Bone Morphogenetic Protein ◽  
Controlled Trial ◽  
Scaphoid Nonunion ◽  
Journal Articles ◽  
Level Of Evidence ◽  
Carpal Collapse ◽  
Morphogenetic Protein ◽  
Combination Of Methods

Abstract Background Scaphoid nonunion can lead to carpal collapse and osteoarthritis, a painfully debilitating problem. Bone morphogenetic protein (BMP) has been successfully implemented to augment bone healing in other circumstances, but its use in scaphoid nonunion has yielded conflicting results. Case Description The purpose of this study is to assess the outcomes and complications of scaphoid nonunion treated surgically with BMP. Literature Review A literature review of all available journal articles citing the use of BMP in scaphoid nonunion surgery from 2002 to 2019 was conducted. We included studies that used BMP as an adjunct to surgical treatment for scaphoid nonunions in both the primary and revision settings with computed tomography determination of union. Demographic information, dose of BMP, tobacco use, outcomes, and complications were recorded. A total of 21 cases were included from four different studies meeting inclusion criteria. Clinical Relevance The union rates were 90.5% overall, 100% for primary surgeries, and 77.8% for revision surgeries. Five patients (24%) experienced 11 complications, including four cases (19%) of heterotrophic ossification. Use of BMP in scaphoid nonunion surgery resulted in a 90.5% overall union rate but was also associated with complications such as heterotopic ossification. All included studies used BMP to augment bone graft, screw or wire fixation, or a combination of methods. The efficacy of BMP in scaphoid nonunion is unclear, and a sufficiently powered, randomized controlled trial is needed to determine optimal fixation methods, dosing, and morbidity of the use of BMP. Level of Evidence This is a Level IC, therapeutic interventional study.

scholarly journals The influences of walking, running and stair activity on knee articular cartilage: Quantitative MRI using T1 rho and T2 mapping

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0187008 ◽  
Author(s):  
Meng Chen ◽  
Lin Qiu ◽  
Si Shen ◽  
Fei Wang ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
T2 Mapping ◽  
Quantitative Mri ◽  
T1 Rho
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