Quantitative analysis Of hepatocellular adenoma and focal nodular hyperplasia in the hepatobiliary phase: External validation of LLCER method using gadobenate dimeglumine as contrast agent

2017 ◽  
Vol 47 (3) ◽  
pp. 860-861 ◽  
Author(s):  
Maarten G. Thomeer ◽  
Bibiche Gest ◽  
Hermen van Beek ◽  
Marianne De Vries ◽  
Roy Dwarkasing ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Contrast Agent ◽  
Focal Nodular Hyperplasia ◽  
External Validation ◽  
Hepatocellular Adenoma ◽  
Gadobenate Dimeglumine ◽  
Hepatobiliary Phase ◽  
Nodular Hyperplasia

Intrapatient Comparison of the Hepatobiliary Phase of Gd-BOPTA and Gd-EOB-DTPA in the Differentiation of Hepatocellular Adenoma From Focal Nodular Hyperplasia

2018 ◽  
Vol 49 (3) ◽  
pp. 700-710 ◽  
Author(s):  
Inge J.S.M.L. Vanhooymissen ◽  
Maarten G. Thomeer ◽  
Loes M.M. Braun ◽  
Bibiche Gest ◽  
Sebastiaan van Koeverden ◽  
...  
Keyword(s):  
Focal Nodular Hyperplasia ◽  
Hepatocellular Adenoma ◽  
Hepatobiliary Phase ◽  
Nodular Hyperplasia

scholarly journals Laparoscopic Hepatectomy with Selective Hepatic Artery Clamping for A Hyperintense Hepatic Adenoma on Hepatospecific Gadolinium-Enhanced Magnetic Resonance Imaging: The Great Pretender

2019 ◽  
pp. 1-4
Author(s):  
Rodrigo Cañada Trofo Surjan ◽  
Rodrigo Cañada Trofo Surjan ◽  
Andrea Zaidan de Almeida Barros ◽  
Roberto Blasbalg ◽  
Sergio do Prado Silveira ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hepatic Artery ◽  
Focal Nodular Hyperplasia ◽  
Laparoscopic Hepatectomy ◽  
Hepatocellular Adenoma ◽  
Hepatobiliary Phase ◽  
Hepatic Tumors ◽  
Resonance Imaging ◽  
Nodular Hyperplasia

Introduction: Focal nodular hyperplasia and hepatocellular adenoma are benign hepatic tumors and differential diagnosis is important as hepatic adenomas may complicate with hemorrhage and malignant transformation. Magnetic resonance imaging with gadolinium-enhanced contrast agents is the best noninvasive diagnostic tool for benign hepatic tumors. Nevertheless, atypical radiological findings can make differential diagnosis a challenge. Presentation of case: We report a young female patient with large hepatic benign tumor with intralesional hemorrhage that disclosed hyper-intensity on hepatobiliary phase on a gadolinium-enhanced magnetic resonance imaging study, suggestive of focal nodular hyperplasia. As this type of tumor usually do not complicate with bleeding, surgical resection was proposed and a laparoscopic right posterior hepatic sectionectomy with selective hepatic artery clamping was performed. Pathology disclosed an inflammatory hepatic adenoma. Discussion: Hepatic adenomas may present as hyper-intense tumors on hepatobiliary phase of gadoliniumenhanced magnetic resonance imaging. Surgical resection still has a role on the treatment of benign hepatic tumors. Laparoscopic liver resections must be considered, even when a major hepatectomy is planned, as this approach has proved safe and effective. Selective hepatic artery clamping during minimally invasive liver surgery may be an option to reduce intraoperative bleeding, remnant liver ischemia and postoperative hepatic failure. Conclusion: We reported a young female patient with a benign hepatic tumor complicated with hemorrhage suggestive of a focal nodular hyperplasia on gadolinium-enhanced magnetic resonance imaging study. A laparoscopic hepatectomy was performed and final pathology disclosed an inflammatory hepatocellular adenoma.

scholarly journals CONTRAST-ENCHANCED ULTRASOUND IN THE DIFFERENTIAL DIAGNOSIS OF FOCAL NODULAR HYPERPLASIA AND HEPATIC ADENOMA

2019 ◽  
Vol 26 (2) ◽  
pp. 50-63 ◽  
Author(s):  
Alexey N. Katrich ◽  
Nikolai S. Ryabinin ◽  
Sergey V. Polshikov ◽  
Nikita A. Katrich
Keyword(s):  
Differential Diagnosis ◽  
Contrast Agent ◽  
Focal Nodular Hyperplasia ◽  
Ultrasound Contrast Agent ◽  
Hepatocellular Adenoma ◽  
Morphological Data ◽  
Arterial Phase ◽  
Benign Tumors ◽  
Focal Lesions ◽  
Nodular Hyperplasia

Aim. To increase the effectiveness of the differential diagnosis of benign focal lesions of the liver using contrast-enhanced ultrasound (CEUS).Materials and methods. A retrospective analysis of the examination results of 37 patients with morphologically confi rmed liver benign tumors was carried out. According to the morphological data, the patients were divided into two groups: 22 patients with focal nodular hyperplasia (FNH) and 15 patients with hepatocellular adenoma (HCA). All the patients underwent multiparametric ultrasound examination using CEUS.Results. According to the obtained data, despite the nearly equal intensity of fi lling FNH and HCA with a contrast agent (96% and 80%, accordingly), FNH is characterized by an earlier contrasting (WASH IN) pattern in the arterial phase (AF), with the ‘onset of contrasting in the focus’ parameter being signifi cantly different from HCA (p<0.05). Specifi c signs of FNH included the following: the spoke-wheel pattern and an increased intensity of ultrasound contrast agent (USCA) accumulation — 96% of cases; ‘center-to-edge’ fi lling — 86% of cases. WASH-OUT is not a typical sign of FNA. A complete (100% of cases) and intensive (80% of cases) centripetal (80% of cases) fi lling is characteristic of HCA. No specifi c types of vascular pattern were observed. In 6 (40%) patients, WASH-OUT and ‘relative hyperechoic’ were detected in the portal phase.Conclusion. CEUS is established to be an effective method of the differential diagnosis of FNH and HCA. 

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