Breath-hold and free-breathing 2D phase-contrast MRI for quantification of oxygen-induced changes of pulmonary circulation dynamics in healthy volunteers

2017 ◽  
Vol 46 (6) ◽  
pp. 1698-1706 ◽  
Author(s):  
Christoph P. Czerner ◽  
Hinrich B. Winther ◽  
Antonia Zapf ◽  
Frank Wacker ◽  
Jens Vogel-Claussen
2019 ◽  
Vol 13 (4) ◽  
pp. 640-647 ◽  
Author(s):  
Zhenglun Alan Wei ◽  
Phillip M. Trusty ◽  
Yingnan Zhang ◽  
Elaine Tang ◽  
Kevin K. Whitehead ◽  
...  

2013 ◽  
Vol 71 (6) ◽  
pp. 2172-2179 ◽  
Author(s):  
Mehmet Akçakaya ◽  
Praveen Gulaka ◽  
Tamer A. Basha ◽  
Long H. Ngo ◽  
Warren J. Manning ◽  
...  

2013 ◽  
Vol 38 (5) ◽  
pp. 1054-1062 ◽  
Author(s):  
Simon Bauer ◽  
Michael Markl ◽  
Daniela Föll ◽  
Maximilian Russe ◽  
Zoran Stankovic ◽  
...  

Diagnostics ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 241 ◽  
Author(s):  
Naoki Ohno ◽  
Tosiaki Miyati ◽  
Tomohiro Noda ◽  
Noam Alperin ◽  
Takashi Hamaguchi ◽  
...  

We propose fast phase-contrast cine magnetic resonance imaging (PC-cine MRI) to allow breath-hold acquisition, and we compared intracranial hemo- and hydrodynamic parameters obtained during breath holding between full inspiration and end expiration. On a 3.0 T MRI, using electrocardiogram (ECG)-synchronized fast PC-cine MRI with parallel imaging, rectangular field of view, and segmented k-space, we obtained velocity-mapped phase images at the mid-C2 level with different velocity encoding for transcranial blood flow and cerebrospinal-fluid (CSF) flow. Next, we calculated the peak-to-peak amplitudes of cerebral blood flow (ΔCBF), cerebral venous outflow, intracranial volume change, CSF pressure gradient (ΔPG), and intracranial compliance index. These parameters were compared between the proposed and conventional methods. Moreover, we compared these parameters between different utilized breath-hold maneuvers (inspiration, expiration, and free breathing). All parameters derived from the fast PC method agreed with those from the conventional method. The ΔPG was significantly higher during full inspiration breath holding than at the end of expiration and during free breathing. The proposed fast PC-cine MRI reduced scan time (within 30 s) with good agreement with conventional methods. The use of this method also makes it possible to assess the effects of respiration on intracranial hemo- and hydrodynamics.


Open Heart ◽  
2020 ◽  
Vol 7 (2) ◽  
pp. e001323
Author(s):  
Litten Bertelsen ◽  
Niels Vejlstrup ◽  
Laura Andreasen ◽  
Morten Salling Olesen ◽  
Jesper Hastrup Svendsen

ObjectiveCardiac MRI is quickly emerging as the gold standard for assessment of mitral regurgitation, most commonly with the indirect method subtracting forward flow in aorta from volumetric segmentation of the left ventricle. We aimed to investigate how aortic flow measurements with increasing distance from the aortic valve affect calculated mitral regurgitations and whether measurements were influenced by breath-hold regimen.MethodsFree-breathing and breath-hold phase contrast flows were measured in aorta at valve level, sinotubular (ST) junction, mid-ascending aorta and in the pulmonary trunk. Flow measurements were pairwise compared, and subsequently, after exclusion of patients with visible mitral and tricuspid regurgitations for left-sided and right-sided comparisons, respectively, flow-measured stroke volumes were compared with ventricular volumetric segmentations.ResultsThirty-nine participants without arrhythmias or structural abnormalities of the large vessels were included. Stroke volumes measured with free-breathing and breath-hold flow decreased equally with increasing distance to the aortic valves (breath-hold flow: aortic valve 105.6±20.8 mL, ST junction 101.5±20.7 mL, mid-ascending aorta 98.1±21.5 mL). After exclusion of atrioventricular regurgitations, stroke volumes determined by volumetric measurements were higher compared with values determined by flow measurements, corresponding to ‘false’ atrioventricular regurgitations of 8.0%±5.8% with flow measured at valve level, 11.6%±5.2% at the ST junction and 15.3%±5.0% at the mid-ascending aorta.ConclusionsStroke volumes determined by flow decrease throughout the proximal aorta and are systematically lower than volumetrically measured stroke volumes. The indirect method systematically overestimates mitral regurgitations, especially with increasing distance from the aortic valves.


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