MRI assessment of pathological stage and surgical margins in anterior prostate cancer (APC) using subjective and quantitative analysis

2016 ◽  
Vol 45 (5) ◽  
pp. 1296-1303 ◽  
Author(s):  
Nicola Schieda ◽  
Christopher S. Lim ◽  
Muhammad Idris ◽  
Robert S. Lim ◽  
Christopher Morash ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Quantitative Analysis ◽  
Surgical Margins ◽  
Pathological Stage ◽  
Anterior Prostate ◽  
Anterior Prostate Cancer

MP48-17 ANTERIOR PROSTATE CANCER: CLINICOPATHOLOGIC CHARACTERIZATION WITH BIOPSY CORRELATION

2015 ◽  
Vol 193 (4S) ◽  
Author(s):  
Martin Magers ◽  
Tianyu Zhan ◽  
Aaron Udager ◽  
Brent Hollenbeck ◽  
John Wei ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Anterior Prostate ◽  
Anterior Prostate Cancer

Identification of prostate cancer risk categories according to surgical margins status, pathological stage and Gleason score

2013 ◽  
Vol 20 (11) ◽  
pp. 1097-1103 ◽  
Author(s):  
Riccardo Schiavina ◽  
Marco Borghesi ◽  
Michelangelo Fiorentino ◽  
Eugenio Brunocilla ◽  
Fabio Manferrari ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Gleason Score ◽  
Prostate Cancer Risk ◽  
Surgical Margins ◽  
Pathological Stage ◽  
Risk Categories

The importance of surgical margins for biochemical recurrence in high-risk prostate cancer patients.

2017 ◽  
Vol 35 (6_suppl) ◽  
pp. 75-75
Author(s):  
Victor Srougi ◽  
Rafael Sanchez-Salas ◽  
Fernando P. Secin ◽  
Igor Nunes-Silva ◽  
Mohammed Baghdadi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Gleason Score ◽  
Biochemical Recurrence ◽  
Surgical Margins ◽  
Pathological Stage ◽  
Free Survival ◽  
Positive Surgical Margins ◽  
High Risk Prostate Cancer ◽  
Risk Prostate Cancer

75 Background: High-risk prostate cancer (PCa) is associated with greater risk of biochemical recurrence and cancer specific lethality. A multi-modal treatment is required for this group of patients, comprising surgery as part of it. However, the role of surgery as monotherapy is still under investigation. The purpose of this study is to analyze the influence of surgical margins on biochemical recurrence (BCR) among patients with high-risk prostate cancer (PCa) treated with robot assisted radical prostatectomy (RARP) since the start of our robotic program. Methods: We retrospectively analyzed our prospectively collected database of 5695 minimally invasive prostatectomies performed between 2000 and 2015. Clinical, pathological and oncological outcomes were evaluated in patients fulfilling Damico´s high risk characteristics. Primary endpoint was BCR, defined as post-operative PSA ≥ 0,2. Patients with neoadjuvant or adjuvant therapy were excluded. BCR was estimated with Kaplan-Meier curves. Cox proportional hazards regression was used to estimate variables associated with BCR. Results: We identified 199 high-risk PCa patients treated with RARP during the study period. Gleason score ≥ 8, PSA ≥ 20 and clinical stage ≥ T2c were present in 44%, 35% and 11% of the patients, respectively. The rate of positive surgical margins was 25%. With a median follow-up of 23 months (interquartile 12 – 34 months), 31% of the patients had BCR. Five-year BCR-free survival was 34,5%. Gleason score ≥ 8, PSA ≥ 20 and positive surgical margins were not predictors of BCR. A positive correlation of pathological stage ≥ T3 and BCR was found with (HR = 2.9; 95% CI = 1.2-6.9). Conclusions: The 5-years BCR-free survival was poor despite a low rate of positive surgical margins, when compared to historical series. We found that pathological stage ≥ T3 has a significant correlation with the BCR and that negative surgical margins do not assure good prognosis for high-risk patients.

Anterior Prostate Cancer: Diagnostic Performance of T2-Weighted MRI and an Apparent Diffusion Coefficient Map

2015 ◽  
Vol 205 (2) ◽  
pp. W185-W192 ◽  
Author(s):  
Hiroshi Shinmoto ◽  
Chiharu Tamura ◽  
Shigeyoshi Soga ◽  
Teppei Okamura ◽  
Akio Horiguchi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Diagnostic Performance ◽  
Cancer Diagnostic ◽  
Apparent Diffusion ◽  
Anterior Prostate ◽  
Anterior Prostate Cancer
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