Apparent diffusion coefficient measurement in glioma: Influence of region-of-interest determination methods on apparent diffusion coefficient values, interobserver variability, time efficiency, and diagnostic ability

2016 ◽  
Vol 45 (3) ◽  
pp. 722-730 ◽  
Author(s):  
Xu Han ◽  
Shiteng Suo ◽  
Yawen Sun ◽  
Jinyan Zu ◽  
Jianxun Qu ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Interobserver Variability ◽  
Region Of Interest ◽  
Diagnostic Ability ◽  
Time Efficiency ◽  
Apparent Diffusion Coefficient Values ◽  
Apparent Diffusion ◽  
Coefficient Measurement ◽  
Determination Methods

scholarly journals Region of interest demarcation for quantification of the apparent diffusion coefficient in breast lesions and its interobserver variability

2015 ◽  
Vol 21 (2) ◽  
pp. 123-127 ◽  
Author(s):  
Luísa Nogueira ◽  
Sofia Brandão ◽  
Eduarda Matos ◽  
Rita Gouveia Nunes ◽  
Hugo Alexandre Ferreira ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Interobserver Variability ◽  
Region Of Interest ◽  
Breast Lesions ◽  
Apparent Diffusion

Diffusion tensor imaging reveals microstructural differences between subtypes of trigeminal neuralgia

2020 ◽  
Vol 133 (2) ◽  
pp. 573-579 ◽  
Author(s):  
Matthew S. Willsey ◽  
Kelly L. Collins ◽  
Erin C. Conrad ◽  
Heather A. Chubb ◽  
Parag G. Patil
Keyword(s):  
Diffusion Coefficient ◽  
Diffusion Tensor Imaging ◽  
Trigeminal Neuralgia ◽  
Apparent Diffusion Coefficient ◽  
Diffusion Tensor ◽  
Statistical Significance ◽  
Region Of Interest ◽  
Pain Syndrome ◽  
Radial Diffusivity ◽  
Apparent Diffusion

OBJECTIVETrigeminal neuralgia (TN) is an uncommon idiopathic facial pain syndrome. To assist in diagnosis, treatment, and research, TN is often classified as type 1 (TN1) when pain is primarily paroxysmal and episodic or type 2 (TN2) when pain is primarily constant in character. Recently, diffusion tensor imaging (DTI) has revealed microstructural changes in the symptomatic trigeminal root and root entry zone of patients with unilateral TN. In this study, the authors explored the differences in DTI parameters between subcategories of TN, specifically TN1 and TN2, in the pontine segment of the trigeminal tract.METHODSThe authors enrolled 8 patients with unilateral TN1, 7 patients with unilateral TN2, and 23 asymptomatic controls. Patients underwent DTI with parameter measurements in a region of interest within the pontine segment of the trigeminal tract. DTI parameters were compared between groups.RESULTSIn the pontine segment, the radial diffusivity (p = 0.0049) and apparent diffusion coefficient (p = 0.023) values in TN1 patients were increased compared to the values in TN2 patients and controls. The DTI measures in TN2 were not statistically significant from those in controls. When comparing the symptomatic to asymptomatic sides in TN1 patients, radial diffusivity was increased (p = 0.025) and fractional anisotropy was decreased (p = 0.044) in the symptomatic sides. The apparent diffusion coefficient was increased, with a trend toward statistical significance (p = 0.066).CONCLUSIONSNoninvasive DTI analysis of patients with TN may lead to improved diagnosis of TN subtypes (e.g., TN1 and TN2) and improve patient selection for surgical intervention. DTI measurements may also provide insights into prognosis after intervention, as TN1 patients are known to have better surgical outcomes than TN2 patients.

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