scholarly journals Risk stratification of prostate cancer utilizing apparent diffusion coefficient value and lesion volume on multiparametric MRI

2016 ◽  
Vol 45 (2) ◽  
pp. 610-616 ◽  
Author(s):  
Simpa S. Salami ◽  
Eran Ben-Levi ◽  
Oksana Yaskiv ◽  
Baris Turkbey ◽  
Robert Villani ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diffusion Coefficient ◽  
Risk Stratification ◽  
Apparent Diffusion Coefficient ◽  
Multiparametric Mri ◽  
Lesion Volume ◽  
Apparent Diffusion Coefficient Value ◽  
Apparent Diffusion

scholarly journals Assessment of Apparent Diffusion Coefficient Values as Predictor of Aggressiveness in Peripheral Zone Prostate Cancer: Comparison with Gleason Score

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Shayan Sirat Maheen Anwar ◽  
Zahid Anwar Khan ◽  
Rana Shoaib Hamid ◽  
Fahd Haroon ◽  
Raza Sayani ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Gleason Score ◽  
Case Series ◽  
Adc Value ◽  
Apparent Diffusion Coefficient Values ◽  
Apparent Diffusion Coefficient Value ◽  
Apparent Diffusion ◽  
Adc Values

Purpose. To determine association between apparent diffusion coefficient value on diffusion-weighted imaging and Gleason score in patients with prostate cancer. Methods. This retrospective case series was conducted at Radiology Department of Aga Khan University between June 2009 and June 2011. 28 patients with biopsy-proven prostate cancer were included who underwent ultrasound guided sextant prostate biopsy and MRI. MRI images were analyzed on diagnostic console and regions of interest were drawn. Data were entered and analyzed on SPSS 20.0. ADC values were compared with Gleason score using one-way ANOVA test. Results. In 28 patients, 168 quadrants were biopsied and 106 quadrants were positive for malignancy. 89 lesions with proven malignancy showed diffusion restriction. The mean ADC value for disease with a Gleason score of 6 was 935 mm2/s (SD=248.4 mm2/s); Gleason score of 7 was 837 mm2/s (SD=208.5 mm2/s); Gleason score of 8 was 614 mm2/s (SD=108 mm2/s); and Gleason score of 9 was 571 mm2/s (SD=82 mm2/s). Inverse relationship was observed between Gleason score and mean ADC values. Conclusion. DWI and specifically quantitative ADC values may help differentiate between low-risk (Gleason score, 6), intermediate-risk (Gleason score, 7), and high-risk (Gleason score 8 and 9) prostate cancers, indirectly determining the aggressiveness of the disease.

scholarly journals Multiparametric MRI Apparent Diffusion Coefficient (ADC) Accuracy in Diagnosing Clinically Significant Prostate Cancer

In Vivo ◽  
2017 ◽  
Vol 31 (3) ◽  
pp. 415-418 ◽  
Author(s):  
PIETRO PEPE ◽  
DAVIDE D’URSO ◽  
ANTONIO GARUFI ◽  
GIANDOMENICO PRIOLO ◽  
MICHELE PENNISI ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Multiparametric Mri ◽  
Apparent Diffusion ◽  
Clinically Significant
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