scholarly journals Evaluation of optimized breath-hold and free-breathing 3D ultrashort echo time contrast agent-free MRI of the human lung

2015 ◽  
Vol 43 (5) ◽  
pp. 1230-1238 ◽  
Author(s):  
Neville D. Gai ◽  
Ashkan Malayeri ◽  
Harsh Agarwal ◽  
Robert Evers ◽  
David Bluemke
Keyword(s):  
Contrast Agent ◽  
Human Lung ◽  
Free Breathing ◽  
Breath Hold ◽  
Ultrashort Echo Time ◽  
Echo Time

scholarly journals Transient Severe Respiratory Motion Artifacts After Application of Gadoxetate Disodium: What We Currently Know

2017 ◽  
Vol 190 (01) ◽  
pp. 20-30 ◽  
Author(s):  
Lennart Well ◽  
Julius Weinrich ◽  
Gerhard Adam ◽  
Peter Bannas
Keyword(s):  
Risk Factors ◽  
Contrast Agent ◽  
Potential Risk ◽  
Free Breathing ◽  
Underlying Mechanism ◽  
Motion Artifacts ◽  
Arterial Phase ◽  
Breath Hold ◽  
Gadoxetate Disodium ◽  
Potential Risk Factors

Background Gadoxetate disodium is an intracellular contrast agent for magnetic resonance imaging (MRI) of the liver. Recent publications revealed that injection of gadoxetate disodium can lead to imaging artifacts due to transient severe motion (TSM) in the arterial phase of contrast-enhanced liver MRI. In this review we present and discuss published frequencies of TSM, contrast injection and image acquisition protocols, potential risk factors, and proposed strategies to avoid or minimize the effects of TSM. Method Two reviewers independently searched the PubMed search engine for “transient severe motion artifact” and related terms. Reference lists of retrieved articles were also searched. The two reviewers selected in consensus nine studies that reported both frequencies of TSM and potential risk factors. Study data were extracted by both reviewers, and disagreement was resolved by consensus. Results and Conclusion TSM is caused by impaired breath-hold ability after gadoxetate disodium injection and occurs in 5 – 22 % of patients. The dose of applied contrast agent, repeated exposure to gadoxetate disodium, high BMI and pulmonary disease have been described as potential risk factors for TSM. However, there are only few concordant results on this topic and the pathophysiology of TSM has not been identified. Proposed strategies for the prevention of TSM are slow injection rates and low doses of diluted gadoxetate disodium. Accelerated and free-breathing MRI sequence protocols and breath-hold training may minimize the effects of TSM. Further prospective studies are needed to confirm these strategies and to identify the underlying mechanism of TSM. Key Points  Citation Format

scholarly journals Oxygen-enhanced 3D radial ultrashort echo time magnetic resonance imaging in the healthy human lung

2014 ◽  
Vol 27 (12) ◽  
pp. 1535-1541 ◽  
Author(s):  
Stanley J. Kruger ◽  
Sean B. Fain ◽  
Kevin M. Johnson ◽  
Robert V. Cadman ◽  
Scott K. Nagle
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Human Lung ◽  
Resonance Imaging ◽  
Healthy Human ◽  
Ultrashort Echo Time ◽  
Echo Time

scholarly journals Free-breathing pediatric chest MRI: Performance of self-navigated golden-angle ordered conical ultrashort echo time acquisition

2017 ◽  
Vol 47 (1) ◽  
pp. 200-209 ◽  
Author(s):  
Evan J. Zucker ◽  
Joseph Y. Cheng ◽  
Anshul Haldipur ◽  
Michael Carl ◽  
Shreyas S. Vasanawala
Keyword(s):  
Free Breathing ◽  
Ultrashort Echo Time ◽  
Golden Angle ◽  
Pediatric Chest ◽  
Echo Time ◽  
Time Acquisition

scholarly journals Applying Compressed Sensing Volumetric Interpolated Breath-Hold Examination and Spiral Ultrashort Echo Time Sequences for Lung Nodule Detection in MRI

Diagnostics ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 93
Author(s):  
Yu-Sen Huang ◽  
Emi Niisato ◽  
Mao-Yuan Marine Su ◽  
Thomas Benkert ◽  
Ning Chien ◽  
...  
Keyword(s):  
Detection Rate ◽  
Lung Nodule ◽  
Chest Ct ◽  
Breath Hold ◽  
Limits Of Agreement ◽  
Ultrashort Echo Time ◽  
Nodule Size ◽  
Lung Nodule Detection ◽  
Nodule Detection ◽  
Echo Time

This prospective study aimed to investigate the ability of spiral ultrashort echo time (UTE) and compressed sensing volumetric interpolated breath-hold examination (CS-VIBE) sequences in magnetic resonance imaging (MRI) compared to conventional VIBE and chest computed tomography (CT) in terms of image quality and small nodule detection. Patients with small lung nodules scheduled for video-assisted thoracoscopic surgery (VATS) for lung wedge resection were prospectively enrolled. Each patient underwent non-contrast chest CT and non-contrast MRI on the same day prior to thoracic surgery. The chest CT was performed to obtain a standard reference for nodule size, location, and morphology. The chest MRI included breath-hold conventional VIBE and CS-VIBE with scanning durations of 11 and 13 s, respectively, and free-breathing spiral UTE for 3.5–5 min. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and normal structure visualizations were measured to evaluate MRI quality. Nodule detection sensitivity was evaluated on a lobe-by-lobe basis. Inter-reader and inter-modality reliability analyses were performed using the Cohen κ statistic and the nodule size comparison was performed using Bland–Altman plots. Among 96 pulmonary nodules requiring surgery, the average nodule diameter was 7.7 ± 3.9 mm (range: 4–20 mm); of the 73 resected nodules, most were invasive cancer (74%) or pre-invasive carcinoma in situ (15%). Both spiral UTE and CS-VIBE images achieved significantly higher overall image quality scores, SNRs, and CNRs than conventional VIBE. Spiral UTE (81%) and CS-VIBE (83%) achieved a higher lung nodule detection rate than conventional VIBE (53%). Specifically, the nodule detection rate for spiral UTE and CS-VIBE reached 95% and 100% for nodules >8 and >10 mm, respectively. A 90% detection rate was achieved for nodules of all sizes with a part-solid or solid morphology. Spiral UTE and CS-VIBE under-estimated the nodule size by 0.2 ± 1.4 mm with 95% limits of agreement from −2.6 to 2.9 mm and by 0.2 ± 1.7 mm with 95% limits of agreement from −3.3 to 3.5 mm, respectively, compared to the reference CT. In conclusion, chest CT remains the gold standard for lung nodule detection due to its high image resolutions. Both spiral UTE and CS-VIBE MRI could detect small lung nodules requiring surgery and could be considered a potential alternative to chest CT; however, their clinical application requires further investigation.

scholarly journals Detection of lung lesions in breath-hold VIBE and free-breathing Spiral VIBE MRI compared to CT

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Susann-Cathrin Olthof ◽  
Christian Reinert ◽  
Konstantin Nikolaou ◽  
Christina Pfannenberg ◽  
Sergios Gatidis ◽  
...  
Keyword(s):  
Respiratory Motion ◽  
Pulmonary Nodules ◽  
Visual Image ◽  
Free Breathing ◽  
Breath Hold ◽  
Ultrashort Echo Time ◽  
Single Breath ◽  
Single Breath Hold ◽  
Oncological Patients ◽  
Contrast Enhanced

Abstract Background Detection of pulmonary nodules in MRI requires fast imaging strategies without respiratory motion impairment, such as single-breath-hold Cartesian VIBE. As patients with pulmonary diseases have limited breath-hold capacities, this study investigates the clinical feasibility of non-Cartesian Spiral VIBE under free-breathing compared to CT as the gold standard. Methods Prospective analysis of 27 oncological patients examined in PET/CT and PET/MR. A novel motion-robust 3D ultrashort-echo-time (UTE) MR sequence was evaluated in comparison with CT and conventional breath-hold MR. CT scans were performed under breath-hold in end-expiratory and end-inspiratory position (CT ex, CT in). MR data was acquired with non-contrast-enhanced breath-hold Cartesian VIBE followed by a free-breathing 3D UTE Spiral VIBE. Impact of respiratory motion on pulmonary evaluation was investigated by two readers in Cartesian VIBE, followed by UTE Spiral VIBE and CT ex and the reference standard of CT in. Diagnostic accuracy was calculated, and visual image quality assessed. Results Higher detection rate and sensitivity of pulmonary nodules in free-breathing UTE Spiral VIBE in comparison with breath-hold Cartesian VIBE were found for lesions > 10 mm (UTE Spiral VIBE/VIBE/CT ex): 93%/54%/100%; Lesions 5–10 mm: 67%/25%/ 92%; Lesions < 5 mm: 11%/11%/78%. Lobe-based analysis revealed sensitivities and specificities of 64%/96%/41% and 96%/93%/100% for UTE Spiral VIBE/VIBE/CT ex. Conclusion Free-breathing UTE Spiral VIBE indicates higher sensitivity for detection of pulmonary nodules than breath-hold Cartesian VIBE and is a promising but time-consuming approach. However, sensitivity and specificity of inspiratory CT remain superior in comparison and should be preferred for detection of pulmonary lesions.

scholarly journals Accelerated Stack-of-Spirals Free-Breathing Three-Dimensional Ultrashort Echo Time Lung Magnetic Resonance Imaging: A Feasibility Study in Patients With Breast Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Min Jae Cha ◽  
Hye Shin Ahn ◽  
Hyewon Choi ◽  
Hyun Jeong Park ◽  
Thomas Benkert ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Image Quality ◽  
Parallel Imaging ◽  
Three Dimensional ◽  
Free Breathing ◽  
Resonance Imaging ◽  
Ultrashort Echo Time ◽  
Echo Time

PurposeTo investigate the clinical feasibility of accelerated free-breathing stack-of-spirals (spiral) three-dimensional (3D) ultrashort echo time (UTE) lung magnetic resonance imaging (MRI) using iterative self‐consistent parallel imaging reconstruction from arbitrary k‐space (SPIRiT) algorithm in patients with breast cancer.MethodsThe institutional review board approved this prospective study and patients’ informed consents were obtained. Between June and August 2018, 29 female patients with breast cancer underwent 3-T MRI including accelerated free-breathing spiral 3D UTE (0.98-mm isotropic spatial resolution; echo time, 0.05 msec) of the lungs and thin-section chest computed tomography (CT). Two radiologists evaluated the image quality and pulmonary nodules on MRI were assessed and compared, CT as a reference.ResultsThe pulmonary vessels and bronchi were visible consistently up to the sub-sub-segmental and sub-segmental branch levels, respectively, on accelerated spiral 3D UTE. The overall image quality was evaluated as good and excellent for 70.7% of accelerated spiral 3D UTE images (reviewer [R]1, 72.4% [21/29]; R2, 69.0% [20/29]) and acceptable for 20.7% (both R1 and R2, 20.7% [6/29]). Five patients on CT revealed 141 pulmonary metastatic nodules (5.3 ± 2.6 mm); the overall nodule detection rate of accelerated spiral 3D UTE was sensitivity of 90.8% (128/141), accuracy of 87.7%, and positive predictive value of 96.2%. In the Bland-Altman plot analysis comparing nodule size between CT and MRI, 132/141 nodules (93.6%) were inside the limits of agreement.ConclusionAccelerated free-breathing spiral 3D UTE using the SPIRiT algorithm could be a potential alternative to CT for oncology patients.

scholarly journals Functional MRI of the Lungs Using Single Breath-Hold and Self-Navigated Ultrashort Echo Time Sequences

2020 ◽  
Vol 2 (3) ◽  
pp. e190162 ◽  
Author(s):  
Julius F. Heidenreich ◽  
Simon Veldhoen ◽  
Corona Metz ◽  
Lenon Mendes Pereira ◽  
Thomas Benkert ◽  
...  
Keyword(s):  
Functional Mri ◽  
Breath Hold ◽  
Ultrashort Echo Time ◽  
Single Breath ◽  
Single Breath Hold ◽  
Echo Time ◽  
Time Sequences
Sign in / Sign up

Export Citation Format

Share Document