Whole-body MRI-DWI for assessment of residual disease after completion of therapy in lymphoma: A prospective multicenter study

2015 ◽  
Vol 42 (6) ◽  
pp. 1646-1655 ◽  
Author(s):  
Annemieke S. Littooij ◽  
Thomas C. Kwee ◽  
Bart de Keizer ◽  
Marrie C.A. Bruin ◽  
Ana Coma ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Residual Disease ◽  
Whole Body ◽  
Prospective Multicenter Study ◽  
Whole Body Mri

Whole-body MRI, including diffusion-weighted imaging, for staging lymphoma: Comparison with CT in a prospective multicenter study

2013 ◽  
Vol 40 (1) ◽  
pp. 26-36 ◽  
Author(s):  
Thomas C. Kwee ◽  
Malou A. Vermoolen ◽  
Erik A. Akkerman ◽  
Marie José Kersten ◽  
Rob Fijnheer ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Diffusion Weighted Imaging ◽  
Whole Body ◽  
Prospective Multicenter Study ◽  
Whole Body Mri ◽  
Diffusion Weighted

The Role of Imaging in the Treatment of Patients With Multiple Myeloma in 2016

2016 ◽  
pp. e407-e417 ◽  
Author(s):  
Evangelos Terpos ◽  
Meletios A. Dimopoulos ◽  
Lia A. Moulopoulos
Keyword(s):  
Multiple Myeloma ◽  
Residual Disease ◽  
Conventional Radiography ◽  
Whole Body ◽  
Imaging Method ◽  
Whole Body Mri ◽  
Pet Ct ◽  
Lytic Lesions ◽  
Solitary Bone Plasmacytoma ◽  
Work Up

The novel criteria for the diagnosis of symptomatic multiple myeloma have revealed the value of modern imaging for the management of patients with myeloma. Whole-body low-dose CT (LDCT) has increased sensitivity over conventional radiography for the detection of osteolytic lesions, and several myeloma organizations and institutions have suggested that whole-body LDCT should replace conventional radiography for the work-up of patients with myeloma. MRI is the best imaging method for the depiction of marrow infiltration by myeloma cells. Whole-body MRI (or at least MRI of the spine and pelvis if whole-body MRI is not available) should be performed for all patients with smoldering multiple myeloma with no lytic lesions to look for occult disease, which may justify treatment. In addition, MRI accurately illustrates the presence of plasmacytomas, spinal cord, and/or nerve compression for surgical intervention or radiation therapy; it is also recommended for the work-up of solitary bone plasmacytoma, and it may distinguish malignant from benign fractures (which is very important in cases of patients in biochemical remission with no other signs of progression). Diffusion weighted imaging (DWI) seems to improve MRI diagnosis in patients with myeloma. PET/CT is a functional imaging technique, more sensitive than conventional radiography for the detection of lytic lesions, which probably allows better definition of complete response and minimal residual disease compared with all other imaging methods. PET/CT has shown the best results in the follow-up of patients with myeloma and has an independent prognostic value both at diagnosis and following treatment. PET/CT can also be used for the work-up of solitary bone plasmacytoma and nonsecretory myeloma.

EFFECTIVENESS AND TOLERABILITY OF VERY LOW VOLUME PREPARATION FOR COLONOSCOPY: A PROSPECTIVE, MULTICENTER STUDY

2019 ◽  
Author(s):  
M Maida ◽  
G Morreale ◽  
E Sinagra ◽  
M Manganaro ◽  
D Schillaci ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Prospective Multicenter Study ◽  
Low Volume

Role of pulse oximetric monitoring during gastrointestinal endoscopy. Prospective multicenter study of the Gastroenterological Working Group of the Veszprém Regional Committee of the Hungarian Academy of Sciences (VEAB)

2013 ◽  
Vol 154 (21) ◽  
pp. 825-833
Author(s):  
Zoltán Döbrönte ◽  
Mária Szenes ◽  
Beáta Gasztonyi ◽  
Lajos Csermely ◽  
Márta Kovács ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multicenter Study ◽  
Hungarian Academy ◽  
Prospective Multicenter Study ◽  
Standard Requirement ◽  
Long Duration ◽  
Related Risk ◽  
American Society ◽  
Academy Of Sciences ◽  
Endoscopic Investigation

Introduction: Recent guidelines recommend routine pulse oximetric monitoring during endoscopy, however, this has not been the common practice yet in the majority of the local endoscopic units. Aims: To draw attention to the importance of the routine use of pulse oximetric recording during endoscopy. Method: A prospective multicenter study was performed with the participation of 11 gastrointestinal endoscopic units. Data of pulse oximetric monitoring of 1249 endoscopic investigations were evaluated, of which 1183 were carried out with and 66 without sedation. Results: Oxygen saturation less than 90% was observed in 239 cases corresponding to 19.1% of all cases. It occurred most often during endoscopic retrograde cholangiopancreatography (31.2%) and proximal enteroscopy (20%). Procedure-related risk factors proved to be the long duration of the investigation, premedication with pethidine (31.3%), and combined sedoanalgesia with pethidine and midazolam (34.38%). The age over 60 years, obesity, consumption of hypnotics or sedatives, severe cardiopulmonary state, and risk factor scores III and IV of the American Society of Anestwere found as patient-related risk factors. Conclusion: To increase the safety of patients undergoing endoscopic investigation, pulse oximeter and oxygen supplementation should be the standard requirement in all of the endoscopic investigation rooms. Pulse oximetric monitoring is advised routinely during endoscopy with special regard to the risk factors of hypoxemia. Orv. Hetil., 2013, 154, 825–833.

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