Perfusion measurements of the calf in patients with peripheral arterial occlusive disease before and after percutaneous transluminal angioplasty using Mr arterial spin labeling

2013 ◽  
Vol 40 (4) ◽  
pp. 980-987 ◽  
Author(s):  
Gerd Grözinger ◽  
Rolf Pohmann ◽  
Fritz Schick ◽  
Ulrich Grosse ◽  
Roland Syha ◽  
...  
Keyword(s):  
Peripheral Arterial Occlusive Disease ◽  
Percutaneous Transluminal Angioplasty ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Transluminal Angioplasty ◽  
Arterial Occlusive Disease ◽  
Before And After ◽  
Peripheral Arterial ◽  
Perfusion Measurements ◽  
Percutaneous Transluminal

Abstract 14976: Impact of the Duration of Dual Antiplatelet Therapy in Patients with Peripheral Arterial Occlusive Disease After Percutaneous Transluminal Angioplasty on Clinical Outcomes

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Sungsoo Cho ◽  
Young-Guk Ko ◽  
Dong-Ho Shin ◽  
Jung-Sun Kim ◽  
Byeong-Keuk Kim ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Antiplatelet Therapy ◽  
Peripheral Arterial Occlusive Disease ◽  
Percutaneous Transluminal Angioplasty ◽  
Dual Antiplatelet Therapy ◽  
Transluminal Angioplasty ◽  
Arterial Occlusive Disease ◽  
Optimal Duration ◽  
Peripheral Arterial ◽  
Percutaneous Transluminal

Introduction: Limited data from clinical trials investigating dual antiplatelet therapy (DAPT) in patients with peripheral arterial occlusive disease (PAOD), suggested its potential for a reduction in cardiovascular events. However, the optimal duration of DAPT in patients with symptomatic PAOD after percutaneous transluminal angioplasty (PTA) has not been clearly established. The aim of this study was to determine the optimal duration of DAPT in patients with symptomatic PAOD after PTA. Hypothesis: Longer duration of DAPT is associated with better clinical outcomes in patients with symptomatic PAOD after PTA. Methods: From May 2011 to August 2012, 249 patients with 264 lesions treated with PTA were divided into two groups based on the duration of DAPT [aspirin plus clopidogrel, < 6-month DAPT (n= 120) vs. ≥ 6-month DAPT (n = 129)]. Propensity score-matching analysis was used to adjust for baseline characteristics between two groups. Results: The median follow-up duration was 22.0 ± 8.2 months. In Cox proportional hazard analysis, ≥ 6-month DAPT group was found to be associated with lower rates of MACE (myocardial infarction, stroke, death, and target lesion revascularization; hazard ration [HR]: 2.22; 95% confidence interval [CI]: 1.13-4.35, p = 0.021), and rehospitalization (unstable angina, transient ischemic attack, amputation, and other lesions PTA; HR: 2.29; 95% CI: 1.04-5.01, p = 0.039). Nevertheless, there was no significant association between duration of DAPT and bleeding. Conclusions: DAPT longer than 6 months was associated with lower rates of MACE and rehospitalization in patients with symptomatic PAOD after PTA.

Spontan reversible frühe Restenose nach perkutaner transluminaler Angioplastie

VASA ◽  
1999 ◽  
Vol 28 (1) ◽  
pp. 46-49
Author(s):  
Leu ◽  
Pfammatter ◽  
Schneider ◽  
Enzler ◽  
Leung ◽  
...  
Keyword(s):  
Femoral Artery ◽  
Percutaneous Transluminal Angioplasty ◽  
Initial Result ◽  
Transluminal Angioplasty ◽  
Arterial Occlusive Disease ◽  
Noninvasive Measurements ◽  
The Common ◽  
Late Restenosis ◽  
Peripheral Arterial ◽  
Percutaneous Transluminal

Early reocclusion and late restenosis are well-known problems after percutaneous transluminal angioplasty (PTA). We report here on a phenomenon not described so far in two patients with peripheral arterial occlusive disease who had PTA of the common iliac and the superficial femoral artery, respectively. Both had a good hemodynamic and clinical initial result. However, within two days after PTA symptomatic reobstruction occurred documented by noninvasive measurements. Noteworthy, this reobstruction was spontaneously reversible within days. The possible pathomechanism is discussed.

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