Association between leaflet fusion pattern and thoracic aorta morphology in patients with bicuspid aortic valve

2013 ◽  
Vol 40 (2) ◽  
pp. 294-300 ◽  
Author(s):  
Bryce A. Merritt ◽  
Alexander Turin ◽  
Michael Markl ◽  
S. Chris Malaisrie ◽  
Patrick M. McCarthy ◽  
...  
2018 ◽  
Vol 81 ◽  
pp. 145-148 ◽  
Author(s):  
Francesca Condemi ◽  
Salvatore Campisi ◽  
Magalie Viallon ◽  
Pierre Croisille ◽  
Jean-François Fuzelier ◽  
...  

2015 ◽  
Vol 42 (4) ◽  
pp. 954-963 ◽  
Author(s):  
Bradley D. Allen ◽  
Pim van Ooij ◽  
Alex J. Barker ◽  
Maria Carr ◽  
Maya Gabbour ◽  
...  

VASA ◽  
2010 ◽  
Vol 39 (2) ◽  
pp. 140-144 ◽  
Author(s):  
Tutarel ◽  
Meyer ◽  
Lotz ◽  
Westhoff-Bleck

Background: Bicuspid aortic valve (BAV) is associated with an arteriopathy leading to a progressive dilatation of the aortic root. Recent studies have shown that the whole thoracic aorta is affected by this arteriopathy. Longitudinal data regarding the progression of this arteriopathy in the whole thoracic aorta has not been reported before. Patients and methods: In this retrospective study 40 patients (mean age 28.5 ± 9.1 years) had 2 MR-angiographies (mean interval 37.1 ± 15.2 months). In 23 patients the aortic valve was regurgitant, in 1 stenotic, in 4 combined aortic stenosis / regurgitation was found, while in 12 the valve function was normal. Aortic diameters were measured at 6 different, standardized anatomical points. The influence of demographic and clinical parameters was assessed. Results: A significant increase of the diameter was observed at the aortic root (35.4 ± 5.6 mm → 39.1 ± 6.5 mm, p < 0.001), the ascending aorta (37.3 ± 8.0 mm → 39.5 ± 8.5 mm, p = 0.001), proximal to the innominate artery (29.4 ± 6.1 mm → 31.6 ± 6.8 mm, p = 0.008), and the descending aorta (20.2 ± 2.4 mm → 21.6 ± 4.2 mm, p = 0.03). There was no significant increase proximal (24.0 ± 5.7 mm → 24.6 ± 5.3 mm, p = 0.44) and distal to the left subclavian artery (21.4 ± 4.6 mm → 21.9 ± 4.5 mm, p = 0.19). These observations were independent of the presence of arterial hypertension, a previous operation, gender, and functional status of the aortic valve. Conclusions: The progressive dilatation of the aortic root and ascending aorta that can be observed in patients with BAV was not found in the more distal parts of the thoracic aorta with the exception of the descending aorta in this study. If the dilatation of the descending aorta bears any clinical significance can't be answered with the current data. A prospective study should be performed to confirm these results.


Author(s):  
Faraz Longi ◽  
Felix Orelaru ◽  
Jeffrey Clemence ◽  
Aroma Naeem ◽  
Xiaoting Wu ◽  
...  

Cor et Vasa ◽  
2017 ◽  
Vol 59 (5) ◽  
pp. e468-e473
Author(s):  
Lucie Srncová ◽  
Magdalena Sionová ◽  
Róbert Petr ◽  
Hana Línková

2016 ◽  
Vol 27 (3) ◽  
pp. 518-529 ◽  
Author(s):  
Inês Rodrigues ◽  
Ana F. Agapito ◽  
Lídia de Sousa ◽  
José A. Oliveira ◽  
Luísa M. Branco ◽  
...  

AbstractBackgroundBicuspid aortic valve is the most common CHD. Its association with early valvular dysfunction, endocarditis, thoracic aorta dilatation, and aortic dissection is well established.ObjectiveThe aim of this study was to assess the incidence and predictors of cardiac events in adults with bicuspid aortic valve.MethodsWe carried out a retrospective analysis of cardiac outcomes in ambulatory adults with bicuspid aortic valve followed-up in a tertiary hospital centre. Outcomes were defined as follows: interventional – intervention on the aortic valve or thoracic aorta; medical – death, aortic dissection, aortic valve endocarditis, congestive heart failure, arrhythmias, or ischaemic heart disease requiring hospital admission; and a composite end point of both. Kaplan–Meier curves were generated to determine event rates, and predictors of cardiac events were determined by multivariate analysis.ResultsA total of 227 patients were followed-up over 13±9 years; 29% of patients developed severe aortic valve dysfunction and 12.3% reached ascending thoracic aorta dimensions above 45 mm. At least one cardiac outcome occurred in 38.8% of patients, with an incidence rate at 20 years of follow-up of 47±4%; 33% of patients were submitted to an aortic valve or thoracic aorta intervention. Survival 20 years after diagnosis was 94±2%. Independent predictors of the composite end point were baseline moderate–severe aortic valve dysfunction (hazard ratio, 3.19; 95% confidence interval, 1.35–7.54; p<0.01) and aortic valve leaflets calcification (hazard ratio, 4.72; 95% confidence interval, 1.91–11.64; p<0.005).ConclusionsIn this study of bicuspid aortic valve, the long-term survival was excellent but with occurrence of frequent cardiovascular events. Baseline aortic valve calcification and dysfunction were the only independent predictors of events.


Medicine ◽  
2021 ◽  
Vol 100 (26) ◽  
pp. e26518
Author(s):  
Patrick Geeraert ◽  
Fatemehsadat Jamalidinan ◽  
Ali Fatehi Hassanabad ◽  
Alireza Sojoudi ◽  
Michael Bristow ◽  
...  

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