Diffusion tensor MRI evaluation of the corona radiata, cingulate gyri, and corpus callosum in HIV patients

2013 ◽  
Vol 38 (6) ◽  
pp. 1488-1493 ◽  
Author(s):  
Sarah C.B. Leite ◽  
Diogo G. Corrêa ◽  
Thomas M. Doring ◽  
Tadeu T.A. Kubo ◽  
Tania M. Netto ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Diffusion Tensor Mri ◽  
Hiv Patients ◽  
Corona Radiata ◽  
Cingulate Gyri ◽  
Mri Evaluation

scholarly journals Characteristics of Brain Structure in HIV Male Patients with Syphilis Co-Infection: A Cross-Sectional Study.

2021 ◽  
Author(s):  
Yu Qi ◽  
Yuan-Yuan Wang ◽  
Wei Wang ◽  
Xu-Ze Liu ◽  
Jing Liu ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Infected Male ◽  
Syphilis Infection ◽  
Cross Sectional ◽  
Corona Radiata ◽  
Male Patients ◽  
The Right

Abstract Background To investigate the effect of syphilis infection on the microstructure of white matter (WM) in HIV-infected male patients through comparing the differences of WM between HIV-infected male patients with and without syphilitic infection using diffusion tensor imaging (DTI).Methods 27 HIV-infected male patients with current syphilis or a history of syphilis (HIV+/syphilis+) and 29 HIV-infected male patients without syphilis co-infection history (HIV+/syphilis-) were enrolled. All patients received DTI and comprehensive neuropsychological assessment. Clinical data were compared between the two groups with T-test, Mann-Whitney U Test and Chi-square Test. Tract-based spatial statistics (TBSS) was adopted to analyze the DTI metrics. Multiple linear regression analysis was conducted to investigate the relationships between DTI metrics and clinical variables and cognitive performance. Results In the HIV+/syphilis+ group, decreased AD was found in the right superior corona radiata (SCR-R) and body of corpus callosum (BCC); increased RD was found in the bilateral posterior corona radiata (PCR), the right posterior thalamic radiation (PTR-R), the left SCR (SCR-L), splenium of corpus callosum (SCC) and BCC; decreased FA was found in multiple regions. AD in BCC was negatively correlated with CD4/CD8 ratios. AD in SCR-R was positively correlated with CD4/CD8 ratios. Patients in HIV+/syphilis+ group had a lower score in complex motor skills (CMS). RD in SCC and SCR-L was negatively correlated with CMS; RD in PTR-R was positively correlated with CMS. AD in SCR-R was positively correlated with CMS. Conclusions Compared with patients simply infected with HIV, the integrity of WM is more seriously impaired in HIV-infected patients with syphilis co-infection, and it may accelerate the impairment of cognitive function.

Effects of handedness and gender on macro- and microstructure of the corpus callosum and its subregions: a combined high-resolution and diffusion-tensor MRI study

2004 ◽  
Vol 21 (3) ◽  
pp. 418-426 ◽  
Author(s):  
René Westerhausen ◽  
Frank Kreuder ◽  
Sarah Dos Santos Sequeira ◽  
Christof Walter ◽  
Wolfgang Woerner ◽  
...  
Keyword(s):  
High Resolution ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Diffusion Tensor Mri ◽  
And Gender ◽  
Mri Study ◽  
And Diffusion

scholarly journals Rhesus Monkey and Human Share a Similar Topography of the Corpus Callosum as Revealed by Diffusion Tensor MRI In Vivo

2007 ◽  
Vol 18 (5) ◽  
pp. 1079-1084 ◽  
Author(s):  
S. Hofer ◽  
K.-D. Merboldt ◽  
R. Tammer ◽  
J. Frahm
Keyword(s):  
Corpus Callosum ◽  
Rhesus Monkey ◽  
Diffusion Tensor ◽  
Diffusion Tensor Mri

scholarly journals Diffusion tensor MRI of the corpus callosum in amyotrophic lateral sclerosis

2014 ◽  
Vol 39 (3) ◽  
pp. spcone-spcone
Author(s):  
Molly C. Chapman ◽  
Laura Jelsone-Swain ◽  
Timothy D. Johnson ◽  
Kirsten L. Gruis ◽  
Robert C. Welsh
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Diffusion Tensor Mri ◽  
Lateral Sclerosis

scholarly journals Diffusion tensor MRI of the corpus callosum in amyotrophic lateral sclerosis

2013 ◽  
Vol 39 (3) ◽  
pp. 641-647 ◽  
Author(s):  
Molly C. Chapman ◽  
Laura Jelsone-Swain ◽  
Timothy D. Johnson ◽  
Kirsten L. Gruis ◽  
Robert C. Welsh
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Diffusion Tensor Mri ◽  
Lateral Sclerosis

scholarly journals Abnormalities of Brain White Matter in Type 2 Diabetes Mellitus: A Meta-Analysis of Diffusion Tensor Imaging

2021 ◽  
Vol 13 ◽  
Author(s):  
Li Huang ◽  
Qingqing Zhang ◽  
Tong Tang ◽  
Minguang Yang ◽  
Cong Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Meta Analysis ◽  
Corona Radiata

Aims: The study aimed to conduct a meta-analysis to determine the abnormalities of white matter in patients with type 2 diabetes mellitus (T2DM) by identifying the consistency of diffusion tensor imaging (DTI).Method: The literature for DTI comparing patients with T2DM with controls published before October 30, 2020, were reviewed in PubMed, Web of Science, Embase, CNKI, and Wan Fang databases. The meta-analysis was performed using the activation likelihood estimation (ALE) method, including 12 reports and 381 patients with T2DM.Results: The meta-analysis identified 10 white matter regions that showed a consistent reduction of fractional anisotropy (FA) in patients with T2DM, including genu of the corpus callosum, the body of corpus callosum, bilateral anterior corona radiata, bilateral superior corona radiata, bilateral cingulum, and bilateral superior fronto-occipital fasciculus.Conclusion: This study revealed the abnormal characteristics of white matter in T2DM, which would be helpful to understand the underlying neuropathological and physiological mechanisms of T2DM and provide evidence for clinical diagnosis and treatment.

Diffusion tensor MRI of the corpus callosum and cognitive function in adults born preterm

Neuroreport ◽  
2009 ◽  
Vol 20 (4) ◽  
pp. 424-428 ◽  
Author(s):  
Dimitris Kontis ◽  
Marco Catani ◽  
Marion Cuddy ◽  
Muriel Walshe ◽  
Chiara Nosarti ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Diffusion Tensor Mri

Diffusion tensor imaging in hyperthyroidism: assessment of microstructural white matter abnormality with a tract-based spatial statistical analysis

2020 ◽  
Vol 61 (12) ◽  
pp. 1677-1683 ◽  
Author(s):  
Kerim Aslan ◽  
Hediye Pinar Gunbey ◽  
Sumeyra Cortcu ◽  
Onur Ozyurt ◽  
Ugur Avci ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Imaging Study ◽  
Internal Capsule ◽  
Control Group ◽  
Corona Radiata ◽  
Microstructural Alterations

Background Metabolic, morphological, and functional brain changes associated with a neurological deficit in hyperthyroidism have been observed. However, changes in microstructural white matter (WM), which can explain the underlying pathophysiology of brain dysfunctions, have not been researched. Purpose To assess microstructural WM abnormality in patients with untreated or newly diagnosed hyperthyroidism using tract-based spatial statistics (TBSS). Material and Methods Eighteen patients with hyperthyroidism and 14 age- and sex-matched healthy controls were included in this study. TBSS were used in this diffusion tensor imaging study for a whole-brain voxel-wise analysis of fractional anisotropy, mean diffusivity, axial diffusivity (AD), and radial diffusivity (RD) of WM. Results When compared to the control group, TBSS showed a significant increase in the RD of the corpus callosum, anterior and posterior corona radiata, posterior thalamic radiation, cingulum, superior longitudinal fasciculus, and the retrolenticular region of the internal capsule in patients with hyperthyroidism ( P < 0.05), as well as a significant decrease in AD in the anterior corona radiata and the genu of corpus callosum ( P < 0.05). Conclusion This study showed that more regions are affected by the RD increase than the AD decrease in the WM tracts of patients with hyperthyroidism. These preliminary results suggest that demyelination is the main mechanism of microstructural alterations in the WM of hyperthyroid patients.

scholarly journals MR-MORPHOMETRY AND DTI IN ASSESSING CHANGES OF CORPUS CALLOSUM IN CHILDREN WITH SPASTIC DIPLEGIA

2019 ◽  
pp. 66-71
Author(s):  
V. S. Lvov ◽  
A. V. Pozdniakov ◽  
D. O. Ivanov ◽  
T. A. Aleksandrov ◽  
T. V. Melashenko ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Motor Development ◽  
Comparison Group ◽  
Diffusion Tensor ◽  
Spastic Diplegia ◽  
Diffusion Tensor Mri ◽  
Pathological Changes ◽  
Motor Impairments ◽  
Group 5 ◽  
And Diffusion

The aim of the study was to compare the volumes according to MR morphometry and diffusion values according to diffusion-tensor MRI (DT-MRI) of the corpus callosum in children with spastic diplegia. Methods: the main group consisted of 12 children aged from 1 year 8 months to 4 years 3 months, the comparison group — 5 children with normal motor development, who did not have motor impairments, at the age from 1 year and 3 months up to 3 years 8 months. All patients underwent MR-morphometry, DTI. A comparison was made between the volumes and diffusion values of the corpus callosum between groups. Results: Significant differences were found (p<0,05) in the volume of the genu, splenium and the middle third of the trunk of the corpus callosum. Significant differences (p<0,05) of diffusion values in the middle and posterior third of the trunk of the corpus callosum were also revealed. The data obtained demonstrate the diffuse nature of pathological changes in the corpus callosum in children with spastic diplegia.

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