scholarly journals Discrimination of metastatic lymph nodes in patients with gastric carcinoma using diffusion-weighted imaging

2012 ◽  
Vol 37 (6) ◽  
pp. 1436-1444 ◽  
Author(s):  
Jin Cheng ◽  
Yi Wang ◽  
Jie Deng ◽  
Robert J. McCarthy ◽  
Gongwei Wang ◽  
...  
Keyword(s):  
Gastric Carcinoma ◽  
Lymph Nodes ◽  
Diffusion Weighted Imaging ◽  
Metastatic Lymph Nodes ◽  
Diffusion Weighted ◽  
Metastatic Lymph

Application of apparent diffusion coefficient values derived from diffusion-weighted imaging for assessing different sized metastatic lymph nodes in cervical cancers

2019 ◽  
Vol 61 (6) ◽  
pp. 848-855
Author(s):  
Aining Zhang ◽  
Jiacheng Song ◽  
Zhanlong Ma ◽  
Ting Chen
Keyword(s):  
Lymph Nodes ◽  
Diffusion Weighted Imaging ◽  
Short Axis ◽  
Metastatic Lymph Nodes ◽  
Cervical Cancers ◽  
Diffusion Weighted ◽  
Metastatic Lymph ◽  
Apparent Diffusion ◽  
Group 3 ◽  
Group 1

Background Lymph nodes metastasis is an important factor affecting survival rate and recurrence in cervical cancer patients. Currently, diagnosis of metastatic lymph nodes is mainly based on morphological changes on imaging. However, it is difficult to differentiate normal-sized metastatic lymph nodes with short axis of 5-10mm. Purpose To assess the diagnostic value of apparent diffusion coefficient (ADC) for discriminating different-sized metastatic lymph nodes in patients with cervical cancers. Material and Methods Pathologically confirmed cervical cancer patients were documented from January 2013 to July 2018 in our hospital. A total of 133 patients who underwent conventional MRI and diffusion-weighted imaging with complete pathology were finally enrolled. A total of 157 lymph nodes were harvested and analyzed. All lymph nodes were divided into three groups according to pathology and their short axis (S) measured on axial T2-weighted imaging: normal-sized (5 mm<S<10 mm) benign lymph nodes (Group 1); normal-sized (5 mm<S<10 mm) metastatic lymph nodes (Group 2); enlarged (S≥10 mm) metastatic lymph nodes (Group 3). Mean ADC (ADCmean), minimum ADC (ADCmin), and maximum ADC (ADCmax) values of lymph nodes were analyzed and compared among the three groups. Results ADCmean of Groups 1 and 2 were significantly larger than those of Group 3 ( P<0.001, P=0.005, respectively). ADCmin of Group 1 were significantly larger than those of Groups 2 and 3 ( P<0.001, P<0.001, respectively). ADCmax was not statistically different among the three groups. ADCmean had the relatively highest area under the curve (AUC) of 0.644 for assessing enlarged metastatic lymph nodes, with a sensitivity of 64.4% and specificity of 67.9%. ADCmin had the highest AUC of 0.758 for assessing normal-sized metastatic lymph nodes, with a sensitivity of 84.7% and specificity of 60.7%. Conclusion Diffusion-weighted imaging can be used to differentiate enlarged metastatic lymph nodes from benign lymph nodes, and ADCmin can be further used to identify micro-metastasis in normal-sized lymph nodes.

Endosonographic Diagnosis of Metastatic Lymph Nodes in Gastric Carcinoma

Endoscopy ◽  
1992 ◽  
Vol 24 (S 1) ◽  
pp. 315-319 ◽  
Author(s):  
T. Aibe ◽  
H. Fujimura ◽  
H. Yanai ◽  
K. Okita ◽  
T. Takemoto
Keyword(s):  
Gastric Carcinoma ◽  
Lymph Nodes ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph
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