Quantitative characterization of bone marrow edema pattern in rheumatoid arthritis using 3 tesla MRI

2011 ◽  
Vol 35 (1) ◽  
pp. 211-217 ◽  
Author(s):  
Xiaojuan Li ◽  
Andrew Yu ◽  
Warapat Virayavanich ◽  
Susan M. Noworolski ◽  
Thomas M. Link ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Bone Marrow Edema ◽  
3 Tesla ◽  
Quantitative Characterization ◽  
3 Tesla Mri ◽  
Bone Marrow Edema Pattern ◽  
Marrow Edema

Bone Structure and Perfusion Quantification of Bone Marrow Edema Pattern in the Wrist of Patients with Rheumatoid Arthritis: A Multimodality Study

2014 ◽  
Vol 41 (9) ◽  
pp. 1766-1773 ◽  
Author(s):  
Jose R. Teruel ◽  
Andrew J. Burghardt ◽  
Julien Rivoire ◽  
Waraporn Srikhum ◽  
Susan M. Noworolski ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Bone Density ◽  
Bone Marrow Edema ◽  
Bone Structure ◽  
Trabecular Thickness ◽  
Dce Mri ◽  
Bone Marrow Edema Pattern ◽  
Pannus Tissue ◽  
Marrow Edema

Objective.To quantify bone structure and perfusion parameters in regions of bone marrow edema pattern (BMEP), non-edematous bone marrow (NBM), and pannus tissue areas in the wrists of patients with rheumatoid arthritis (RA) using 3-Tesla (3T) magnetic resonance imaging (MRI), and high resolution peripheral quantitative computed tomography (HR-pQCT).Methods.Sixteen subjects fulfilling American College of Rheumatology classification were imaged using a HR-pQCT system and a 3T MRI scanner with an 8-channel wrist coil. Coronal T2-weighted and dynamic contrast-enhanced (DCE-MRI) images were acquired. BMEP and pannus tissue areas were segmented semiautomatically in T2-weighted images. NBM areas were placed at a similar distance from the joint space as BMEP regions. MR and HR-pQCT images were registered, and bone variables were calculated within the BMEP and NBM regions. Perfusion parameters in BMEP, pannus tissue, and NBM regions were calculated based on the signal-time curve obtained from DCE-MRI.Results.Eighteen BMEP areas were segmented, 15 of them presented proximal to pannus-filled erosions. Significant increases in bone density and trabecular thickness and number were observed in all BMEP regions compared to NMB (p < 0.05). Significantly elevated perfusion measures were observed in both BMEP and pannus tissue regions compared to NBM (p < 0.05).Conclusion.BMEP regions showed significantly increased bone density and structures as well as perfusion measures, suggesting bone remodeling and active inflammation. Combining MRI and HR-pQCT provides a powerful multimodality approach for understanding BMEP and erosions, and for potentially identifying novel imaging markers for disease progression in RA.

scholarly journals Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205902 ◽  
Author(s):  
Claire E. J. Waterborg ◽  
Marije I. Koenders ◽  
Peter L. E. M. van Lent ◽  
Peter M. van der Kraan ◽  
Fons A. J. van de Loo
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Bone Marrow Edema ◽  
Deficient Mice ◽  
Marrow Edema

Bone Marrow Edema Pattern in Osteoarthritic Knees: Correlation between MR Imaging and Histologic Findings

Radiology ◽  
2000 ◽  
Vol 215 (3) ◽  
pp. 835-840 ◽  
Author(s):  
Marco Zanetti ◽  
Elisabeth Bruder ◽  
José Romero ◽  
Juerg Hodler
Keyword(s):  
Bone Marrow ◽  
Mr Imaging ◽  
Bone Marrow Edema ◽  
Bone Marrow Edema Pattern ◽  
Marrow Edema

Bone Marrow Edema Pattern

2014 ◽  
pp. 115-126 ◽  
Author(s):  
Lia Angela Moulopoulos ◽  
Vassilis Koutoulidis
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Edema ◽  
Bone Marrow Edema Pattern ◽  
Marrow Edema

SAT0041 The Course of Bone Marrow Edema in Early Undifferentiated and Rheumatoid Arthritis; A Longitudinal MRI Study on Bone Level

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 663.1-663
Author(s):  
W.P. Nieuwenhuis ◽  
H.W. van Steenbergen ◽  
W. Stomp ◽  
T. Stijnen ◽  
T.W. Huizinga ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Bone Marrow Edema ◽  
Longitudinal Mri ◽  
Bone Level ◽  
Mri Study ◽  
Marrow Edema

scholarly journals Cartilage quantification using contrast-enhanced MRI in the wrist of rheumatoid arthritis: cartilage loss is associated with bone marrow edema

2017 ◽  
Vol 90 (1077) ◽  
pp. 20170167 ◽  
Author(s):  
Motoshi Fujimori ◽  
Satoko Nakamura ◽  
Kiminori Hasegawa ◽  
Kunihiro Ikeno ◽  
Shota Ichikawa ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Bone Marrow Edema ◽  
Cartilage Loss ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Marrow Edema ◽  
Contrast Enhanced Mri

scholarly journals The course of bone marrow edema in early undifferentiated and rheumatoid arthritis; a longitudinal MRI study on bone level

2015 ◽  
pp. n/a-n/a ◽  
Author(s):  
Wouter P. Nieuwenhuis ◽  
Hanna W. van Steenbergen ◽  
Wouter Stomp ◽  
Theo Stijnen ◽  
Tom W.J. Huizinga ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Bone Marrow Edema ◽  
Longitudinal Mri ◽  
Bone Level ◽  
Mri Study ◽  
Marrow Edema
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