scholarly journals 31P MR spectroscopic imaging detects regenerative changes in human liver stimulated by portal vein embolization

2011 ◽  
Vol 34 (2) ◽  
pp. 336-344 ◽  
Author(s):  
Jing Qi ◽  
Amita Shukla-Dave ◽  
Yuman Fong ◽  
Mithat Gönen ◽  
Lawrence H. Schwartz ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Embolization ◽  
Human Liver ◽  
Spectroscopic Imaging ◽  
Mr Spectroscopic Imaging

scholarly journals Fate of the human liver after hemihepatic portal vein embolization: Cell kinetic and morphometric study

Hepatology ◽  
1997 ◽  
Vol 26 (5) ◽  
pp. 1162-1170 ◽  
Author(s):  
H Harada ◽  
H Imamura ◽  
S Miyagawa ◽  
S Kawasaki
Keyword(s):  
Portal Vein ◽  
Portal Vein Embolization ◽  
Human Liver ◽  
Morphometric Study ◽  
Cell Kinetic

scholarly journals Cell atlas of the regenerating human liver after portal vein embolization

2021 ◽  
Author(s):  
Agnieska Brazovskaja ◽  
Tomás Gomes ◽  
Christiane Körner ◽  
Zhisong He ◽  
Theresa Schaffer ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Embolization ◽  
Human Liver ◽  
Portal Blood Flow ◽  
Cell Types ◽  
Cellular Adhesion ◽  
Healthy Human ◽  
Tissue Responses ◽  
Single Nucleus ◽  
Homeostatic Mechanisms

The liver has the remarkable capacity to regenerate. In the clinic, this capacity can be induced by portal vein embolization (PVE), which redirects portal blood flow resulting in liver hypertrophy in locations with increased blood supply, and atrophy of embolized segments. Here we apply single-cell and single-nucleus transcriptomics on healthy, hypertrophied, and atrophied patient-derived liver samples to explore cell states in the liver during regeneration. We first establish an atlas of cell subtypes from the healthy human liver using fresh and frozen tissues, and then compare post-PVE samples with their reference counterparts. We find that PVE alters portal-central zonation of hepatocytes and endothelial cells. Embolization upregulates expression programs associated with development, cellular adhesion and inflammation across cell types. Analysis of interlineage crosstalk revealed key roles for immune cells in modulating regenerating tissue responses. Altogether, our data provides a rich resource for understanding homeostatic mechanisms arising during human liver regeneration and degeneration.

Isolation of primary human hepatocytes from human liver tissue after portal vein embolization

2015 ◽  
Vol 53 (12) ◽  
Author(s):  
M Kluge ◽  
N Raschzok ◽  
A Reutzel-Selke ◽  
H Napierala ◽  
KH Hillebrandt ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Embolization ◽  
Liver Tissue ◽  
Human Liver ◽  
Human Hepatocytes ◽  
Human Liver Tissue ◽  
Primary Human Hepatocytes

Altered phosphoethanolamine levels in alcoholic liver disease assessed by in vivo proton-decoupled 31P MR spectroscopic imaging

2001 ◽  
Vol 120 (5) ◽  
pp. A116-A116
Author(s):  
H SCHLEMMER ◽  
T SAWATZKI ◽  
I DORNACHER ◽  
S SAMMET ◽  
M HELLENSCHMIDT ◽  
...  
Keyword(s):  
Liver Disease ◽  
Alcoholic Liver Disease ◽  
Spectroscopic Imaging ◽  
Mr Spectroscopic Imaging

Portal Vein Embolization

2019 ◽  
Author(s):  
Shelly Brancatelli ◽  
Deb Van Nostran
Keyword(s):  
Portal Vein ◽  
Portal Vein Embolization

In Vivo 1H MR Spectroscopic Imaging of Human Brain

1994 ◽  
Vol 31 (2) ◽  
pp. 185
Author(s):  
Yong Whee Bahk ◽  
Kyung Sub Shinn ◽  
Tae Suk Suh ◽  
Bo Young Choe ◽  
Kyo Ho Choi
Keyword(s):  
Human Brain ◽  
Spectroscopic Imaging ◽  
Mr Spectroscopic Imaging
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