scholarly journals Cardiac troponin T and creatine kinase predict mid-term infarct size and left ventricular function after acute myocardial infarction: A cardiac MR study

2011 ◽  
Vol 33 (4) ◽  
pp. 847-854 ◽  
Author(s):  
Agnes Mayr ◽  
Johannes Mair ◽  
Gert Klug ◽  
Michael Schocke ◽  
Kathrin Pedarnig ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Left Ventricular Function ◽  
Infarct Size ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Left Ventricular ◽  
Cardiac Troponin T ◽  
Mr Study

Plasma cardiac troponin T closely correlates with infarct size in a mouse model of acute myocardial infarction

2002 ◽  
Vol 325 (1-2) ◽  
pp. 87-90 ◽  
Author(s):  
Bernhard Metzler ◽  
Angelika Hammerer-Lercher ◽  
Johannes Jehle ◽  
Hermann Dietrich ◽  
Otmar Pachinger ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Mouse Model ◽  
Infarct Size ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Cardiac Troponin T

scholarly journals Single-Point Cardiac Troponin T at Coronary Care Unit Discharge after Myocardial Infarction Correlates with Infarct Size and Ejection Fraction

2002 ◽  
Vol 48 (9) ◽  
pp. 1432-1436 ◽  
Author(s):  
Mauro Panteghini ◽  
Claudio Cuccia ◽  
Graziella Bonetti ◽  
Raffaele Giubbini ◽  
Franca Pagani ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Ejection Fraction ◽  
Infarct Size ◽  
Cardiac Troponin ◽  
Coronary Care Unit ◽  
Troponin T ◽  
Left Ventricular ◽  
Lv Function ◽  
Cardiac Troponin T ◽  
Coronary Care

Abstract Background: One of the major concerns in replacing creatine kinase MB (CK-MB) with cardiac troponins is the lack of evidence of the ability of troponins to estimate the size of acute myocardial infarction (AMI). We investigated the ability of a single measurement of cardiac troponin T (cTnT) at coronary care unit (CCU) discharge to estimate infarct size and assess left ventricular (LV) function in AMI patients. Methods: We studied 65 AMI patients in whom infarct size was estimated by CK-MB peak concentrations and gated single-photon emission computed tomography (SPECT) myocardial perfusion using technetium-99m sestamibi and LV function by SPECT imaging. Measurements of cTnT and SPECT were performed 72 h (median) after admission (range, 40–160 h). SPECT was also repeated 3 months later. Results: We found a significant correlation between cTnT and both the peak CK-MB concentrations (r = 0.76; P <0.001) and the perfusion defect size at SPECT (r = 0.62; P <0.001). cTnT was inversely related to LV ejection fraction (LVEF) assessed both early (r = −0.56; P <0.001) and 3 months after AMI (r = −0.70; P <0.001). cTnT >2.98 μg/L predicted a LVEF <40% at 3 months with a sensitivity of 86.7%, specificity of 81.4%, and a likelihood ratio for a positive test of 4.7 (95% confidence interval, 4.0–5.4). Conclusions: A single cTnT measurement at CCU discharge after AMI is useful as a noninvasive estimate of infarct size and for the assessment of LV function in routine clinical setting.

scholarly journals Cardiac Troponin T at 96 Hours After Acute Myocardial Infarction Correlates With Infarct Size and Cardiac Function

2006 ◽  
Vol 48 (11) ◽  
pp. 2192-2194 ◽  
Author(s):  
Henning Steen ◽  
Evangelos Giannitsis ◽  
Simon Futterer ◽  
Constanze Merten ◽  
Claus Juenger ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiac Function ◽  
Infarct Size ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Cardiac Troponin T
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