scholarly journals In vivo assessment of peripheral nerve regeneration by diffusion tensor imaging

2011 ◽  
Vol 33 (3) ◽  
pp. 535-542 ◽  
Author(s):  
Shinsuke Morisaki ◽  
Yuko Kawai ◽  
Masahiro Umeda ◽  
Mayumi Nishi ◽  
Ryo Oda ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Diffusion Tensor ◽  
Peripheral Nerve Regeneration ◽  
In Vivo Assessment

scholarly journals Assessment of the Effect of Autograft Orientation on Peripheral Nerve Regeneration Using Diffusion Tensor Imaging

2018 ◽  
Vol 80 (4) ◽  
pp. 384-390 ◽  
Author(s):  
Ashkan Afshari ◽  
Lyly Nguyen ◽  
Nathaniel D. Kelm ◽  
Justine S. Kim ◽  
Nancy L. Cardwell ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Diffusion Tensor ◽  
Peripheral Nerve Regeneration

scholarly journals Assessment of the Effect of Autograft Orientation on Peripheral Nerve Regeneration Utilizing Diffusion Tensor Imaging

2016 ◽  
Vol 41 (9) ◽  
pp. S40
Author(s):  
Ashkan Afshari ◽  
Lyly Nguyen ◽  
Nathaniel D. Kelm ◽  
Justine S. Kim ◽  
Ravinder Bamba ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Diffusion Tensor ◽  
Peripheral Nerve Regeneration

scholarly journals Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model

2018 ◽  
Vol 6 (5) ◽  
pp. 1059-1075 ◽  
Author(s):  
C. R. Carvalho ◽  
S. Wrobel ◽  
C. Meyer ◽  
C. Brandenberger ◽  
I. F. Cengiz ◽  
...  
Keyword(s):  
Sciatic Nerve ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Experimental Work ◽  
Nerve Repair ◽  
Peripheral Nerve Regeneration ◽  
Gellan Gum ◽  
In Vivo Study ◽  
Rat Sciatic Nerve

This experimental work considers the innovative use of the biomaterial Gellan Gum (GG) as a luminal filler for nerve guidance channels.

In vivo evaluation of poly(l-lactic acid) porous conduits for peripheral nerve regeneration

Biomaterials ◽  
1999 ◽  
Vol 20 (12) ◽  
pp. 1109-1115 ◽  
Author(s):  
G.R.D. Evans ◽  
K. Brandt ◽  
M.S. Widmer ◽  
L. Lu ◽  
R.K. Meszlenyi ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
In Vivo Evaluation

Acidic Fibroblast Growth Factor Enhances Peripheral Nerve Regeneration in Vivo

1989 ◽  
Vol 83 (6) ◽  
pp. 1020-1021 ◽  
Author(s):  
Peter G. Cordeiro ◽  
Brooke R. Seckel ◽  
Stuart A. Lipton ◽  
Patricia A. DʼAmore ◽  
John Wagner ◽  
...  
Keyword(s):  
Growth Factor ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Fibroblast Growth Factor ◽  
Peripheral Nerve Regeneration ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor

Effect of Arecoline on Regeneration of Injured Peripheral Nerves

2013 ◽  
Vol 41 (04) ◽  
pp. 865-885 ◽  
Author(s):  
Sheng-Chi Lee ◽  
Chin-Chuan Tsai ◽  
Chun-Hsu Yao ◽  
Yuan-Man Hsu ◽  
Yueh-Sheng Chen ◽  
...  
Keyword(s):  
Sciatic Nerve ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
In Vitro Study ◽  
Control Group ◽  
Neural Cells ◽  
In Vivo Evaluation

The present study provides in vitro and in vivo evaluation of arecoline on peripheral nerve regeneration. In the in vitro study, we found that arecoline at 50 μg/ml could significantly promote the survival and outgrowth of cultured Schwann cells as compared to the controls treated with culture medium only. In the in vivo study, we evaluated peripheral nerve regeneration across a 10-mm gap in the sciatic nerve of the rat, using a silicone rubber nerve chamber filled with the arecoline solution. In the control group, the chambers were filled with normal saline only. At the end of the fourth week, morphometric data revealed that the arecoline-treated group at 5 μg/ml significantly increased the number and the density of myelinated axons as compared to the controls. Immunohistochemical staining in the arecoline-treated animals at 5 μg/ml also showed their neural cells in the L4 and L5 dorsal root ganglia ipsilateral to the injury were strongly retrograde-labeled with fluorogold and lamina I–II regions in the dorsal horn ipsilateral to the injury were significantly calcitonin gene-related peptide-immunolabeled compared with the controls. In addition, we found that the number of macrophages recruited in the distal sciatic nerve was increased as the concentration of arecoline was increased. Electrophysiological measurements showed the arecoline-treated groups at 5 and 50 μg/ml had a relatively larger nerve conductive velocity of the evoked muscle action potentials compared to the controls. These results indicate that arecoline could stimulate local inflammatory conditions, improving the recovery of a severe peripheral nerve injury.

Sign in / Sign up

Export Citation Format

Share Document