Relevance ofb-values in evaluating liver fibrosis: A study in healthy and cirrhotic subjects using two single-shot spin-echo echo-planar diffusion-weighted sequences

2008 ◽  
Vol 28 (2) ◽  
pp. 411-419 ◽  
Author(s):  
Rossano Girometti ◽  
Alessandro Furlan ◽  
Gennaro Esposito ◽  
Massimo Bazzocchi ◽  
Giuseppe Como ◽  
...  
1998 ◽  
Vol 39 (4) ◽  
pp. 440-442 ◽  
Author(s):  
Y. Amano ◽  
T. Kumazaki ◽  
M. Ishihara

Single-shot spin-echo diffusion-weighted echo-planar imaging using a phased-array multicoil was performed to distinguish between normal and cirrhotic livers. Sets of 6 images with different b-values were acquired with breathholding. Significant differences were observed between controls and cirrhosis cases in the signal ratios when the b-value was 383 s/mm2, and apparent diffusion coefficients.


BJR|Open ◽  
2019 ◽  
Vol 1 (1) ◽  
pp. 20180015 ◽  
Author(s):  
Cristina Dudau ◽  
Ashleigh Draper ◽  
Maria Gkagkanasiou ◽  
Geoffrey Charles-Edwards ◽  
Irumee Pai ◽  
...  

Objective: We aimed to compare a newer readout-segmented echoplanar imaging (RS-EPI) technique with the established single shot turbo spin echo (SS-TSE) non-EPI diffusion-weighted imaging (DWI) in detecting surgically validated cholesteatoma. Methods: We retrospectively reviewed 358 consecutive MRI studies in 285 patients in which both RS-EPI and non-EPI DWI sequences were performed. Each diffusion sequence was reviewed independently and scored negative, indeterminate or positive for cholesteatoma in isolation and after reviewing the T1W sequence. Average artefacts scores were evaluated and the lesion size measured as a distortion indicator. The imaging scores were correlated with surgical validation, clinical and imaging follow-up. Results: There were 239 middle ear and central mastoid tract and 34 peripheral mastoid lesions. 102 tympanomastoid operations were performed. The positive predictive value ( PPV), post-operative PPV, primary PPV, negative predictive value were 93%, 95%, 87.5%, 70% for RS-EPI and 92.5%, 93.6%, 90%, 79% for non-EPI DWI. There was good agreement between the two techniques (k = 0.75). Non-EPI DWI is less susceptible to skull base artefacts although the mean cholesteatoma measurement difference was only 0.53 mm. Conclusion: RS-EPI has comparable PPV with non-EPI DWI in both primary and post-operative cholesteatoma but slightly lower negative predictive value. When there is a mismatch, non-EPI DWI better predicts the presence of cholesteatoma. There is good agreement between the sequences for cholesteatoma diagnosis. The T1W sequence is very important in downgrading indeterminate DWI signal lesions to a negative score. Advances in knowledge: This is, to our knowledge, the first study to compare a multishot EPI DWI technique with the established non- EPI DWI in cholesteatoma diagnosis.


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