scholarly journals Chronic recurrent multifocal osteomyelitis (CRMO) with symmetric involvement of both femora: X-ray, bone scintigram, and MR imaging findings in one case

2007 ◽  
Vol 26 (2) ◽  
pp. 422-426 ◽  
Author(s):  
Florian M. Buck ◽  
Thomas C. Treumann ◽  
Hermann Winiker ◽  
Klaus Strobel
1995 ◽  
Vol 19 (6) ◽  
pp. 473-476 ◽  
Author(s):  
Jason M. Stoane ◽  
Maurice R. Poplausky ◽  
Jack O. Haller ◽  
Walter E. Berdon

2018 ◽  
Vol 38 (3) ◽  
pp. 193-195
Author(s):  
Ahmad Jamal ◽  
Biju John ◽  
Mahesh Awariwar ◽  
Shamsher Dalal ◽  
Daljit Singh

Children are often brought to the paediatric out-patient department with non specific aches and pains. Though the majority of them have only a benign diagnosis, some may harbour rare conditions like chronic recurrent multifocal osteomyelitis (CRMO). Case: We describe a 11 year old girl who presented with migratory pain across various parts of hip and lower limbs without any significant signs. After six months of OPD visits, she was diagnosed to have CRMO following an incidental X-ray which led to a musculoskeletal MRI. Conclusion: CRMO is a rare auto-inflammatory disorder which must be kept in mind when encountering a relatively healthy child with poorly defined limb pains along with paucity of signs.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Jeffrey S. Quon ◽  
Anne K. Dzus ◽  
David A. Leswick

Chronic recurrent multifocal osteomyelitis (CRMO) is relatively uncommon. Even though the name suggests it is the result of infection, this is not likely the case. Instead it is more likely the result of genetic, autoimmune, or autoinflammatory causes. Although CRMO has a benign course and responds well to anti-inflammatory medications, it can have a very aggressive clinical and imaging presentation overlapping with infectious osteomyelitis and malignancy. Therefore, radiologists and clinicians need to be aware of its clinical and imaging presentation to avoid morbidity associated with more aggressive treatment. We present the case of a ten-year-old female with CRMO as a solitary expansile-mixed lytic and sclerotic lesion in the distal femoral diaphysis. The diaphyseal location and mixed lytic and sclerotic appearance are less common and have an aggressive imaging appearance. We also review the pathophysiology, imaging findings, and therapeutic approach to this uncommon but clinically important condition.


2015 ◽  
Vol 42 (8) ◽  
pp. 1455-1462 ◽  
Author(s):  
Agnes M. Voit ◽  
Andreas P. Arnoldi ◽  
Hassan Douis ◽  
Felicitas Bleisteiner ◽  
Moritz K. Jansson ◽  
...  

Objective.(1) To examine how many patients have clinically and/or radiologically active chronic recurrent multifocal osteomyelitis (CRMO) ≥ 10 years after first onset of symptoms, and (2) to compare clinical and whole-body magnetic resonance imaging (WB-MRI) findings.Methods.Seventeen patients (82% women) who were diagnosed with childhood-onset CRMO at least 10 years (average 12) before reexamination were reevaluated. Patients completed a standardized questionnaire, and underwent clinical and laboratory investigation and WB-MRI. Clinical features were compared with imaging findings.Results.Five patients were found to be in clinical and radiological remission. One of these patients demonstrated 1 radiologically inactive lesion on WB-MRI. Four patients showed radiologically active lesions despite full clinical remission, 2 of them in 3 vertebral bodies. Spinal involvement in 6 patients (35%) caused vertebral compression fractures, vertebra plana, or vertebral hemifusion. Eight patients presented with ongoing clinical disease activity. When applying a CRMO activity score based on clinical and imaging findings, 2 patients were identified as having pain amplification. Overall, 22/55 known CRMO lesions were identified; 11 of them were radiologically active lesions. Additionally, 14 so far unknown clinically silent lesions were detected: 8 radiologically active lesions and 6 radiologically inactive lesions.Conclusion.CRMO activity on longterm followup might have been underestimated. Our study demonstrates that clinical remission does not necessarily mean radiological remission. We therefore propose that all patients with CRMO, including patients in clinical remission, require longterm clinical followup and should undergo evaluation with WB-MRI on a regular basis until radiological remission or a steady state of disease is achieved.


Author(s):  
Danny L Costantini ◽  
Reza Vali Eman Marie ◽  
Mandy Kohli ◽  
Holly Convery ◽  
Martin Charron ◽  
...  

Radiology ◽  
2009 ◽  
Vol 252 (3) ◽  
pp. 842-851 ◽  
Author(s):  
Jan Fritz ◽  
Nikolay Tzaribatchev ◽  
Claus D. Claussen ◽  
John A. Carrino ◽  
Marius S. Horger

1994 ◽  
Vol 30 (3) ◽  
pp. 421
Author(s):  
Jae Hyoung Kim ◽  
Eui Dong Park ◽  
Hyung Jin Kirn ◽  
Choong Kun Ha

1998 ◽  
Vol 39 (4) ◽  
pp. 639
Author(s):  
Hyun Jin Kim ◽  
Ho Kyu Lee ◽  
Jae Kyun Kim ◽  
Ji Hoon Shin ◽  
Choong Gon Choi ◽  
...  

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