scholarly journals Characterization of breast lesions using the 3D FIESTA sequence and contrast-enhanced magnetic resonance imaging

2007 ◽  
Vol 25 (1) ◽  
pp. 82-88 ◽  
Author(s):  
Catherine S. Klifa ◽  
Ann Shimakawa ◽  
Zaker Siraj ◽  
Jessica E. Gibbs ◽  
Lisa J. Wilmes ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Breast Lesions ◽  
Resonance Imaging ◽  
Contrast Enhanced

Non-contrast enhanced magnetic resonance imaging for characterization of Fontan associated liver disease

2021 ◽  
Author(s):  
Patrick Langguth ◽  
Mona Salehi Ravesh ◽  
Jörg Detlev Moritz ◽  
Katy Rinne ◽  
Paul Lennart Harneit ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Liver Disease ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Contrast Enhanced

scholarly journals Potential of Noncontrast Magnetic Resonance Imaging With Diffusion-Weighted Imaging in Characterization of Breast Lesions

2018 ◽  
Vol 53 (4) ◽  
pp. 229-235 ◽  
Author(s):  
Pascal A.T. Baltzer ◽  
Hubert Bickel ◽  
Claudio Spick ◽  
Georg Wengert ◽  
Ramona Woitek ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Diffusion Weighted Imaging ◽  
Breast Lesions ◽  
Resonance Imaging ◽  
Diffusion Weighted

scholarly journals Three-Dimensional Iron Oxide Nanoparticle-Based Contrast-Enhanced Magnetic Resonance Imaging for Characterization of Cerebral Arteriogenesis in the Mouse Neocortex

2021 ◽  
Vol 15 ◽  
Author(s):  
Till de Bortoli ◽  
Philipp Boehm-Sturm ◽  
Stefan P. Koch ◽  
Melina Nieminen-Kelhä ◽  
Lars Wessels ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Iron Oxide Nanoparticle ◽  
Resonance Imaging ◽  
Non Invasive ◽  
Dsc Mri ◽  
Contrast Enhanced ◽  
Oxide Nanoparticle

Purpose: Subsurface blood vessels in the cerebral cortex have been identified as a bottleneck in cerebral perfusion with the potential for collateral remodeling. However, valid techniques for non-invasive, longitudinal characterization of neocortical microvessels are still lacking. In this study, we validated contrast-enhanced magnetic resonance imaging (CE-MRI) for in vivo characterization of vascular changes in a model of spontaneous collateral outgrowth following chronic cerebral hypoperfusion.Methods: C57BL/6J mice were randomly assigned to unilateral internal carotid artery occlusion or sham surgery and after 21 days, CE-MRI based on T2*-weighted imaging was performed using ultra-small superparamagnetic iron oxide nanoparticles to obtain subtraction angiographies and steady-state cerebral blood volume (ss-CBV) maps. First pass dynamic susceptibility contrast MRI (DSC-MRI) was performed for internal validation of ss-CBV. Further validation at the histological level was provided by ex vivo serial two-photon tomography (STP).Results: Qualitatively, an increase in vessel density was observed on CE-MRI subtraction angiographies following occlusion; however, a quantitative vessel tracing analysis was prone to errors in our model. Measurements of ss-CBV reliably identified an increase in cortical vasculature, validated by DSC-MRI and STP.Conclusion: Iron oxide nanoparticle-based ss-CBV serves as a robust, non-invasive imaging surrogate marker for neocortical vessels, with the potential to reduce and refine preclinical models targeting the development and outgrowth of cerebral collateralization.

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