scholarly journals MRI, volumetry,1H spectroscopy, and cerebropetal blood flowmetry in childhood idiopathic anatomic megalencephaly

2006 ◽  
Vol 24 (2) ◽  
pp. 282-287 ◽  
Author(s):  
Suzanne M. Koudijs ◽  
Jeroen van der Grond ◽  
Mechteld L.C. Hoogendoorn ◽  
Hilleke E. Hulshoff Pol ◽  
Hugo G. Schnack ◽  
...  
Keyword(s):  
Mri Volumetry ◽  
Blood Flowmetry

scholarly journals Cerebellum and brain stem volume loss in relapsing remission multiple sclerosis by MRI volumetry: relation to neurological disability score and number of relapses

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Magdy Elzayady ◽  
Naglaa Lotfy Debees ◽  
Mohamed Khalil ◽  
Mohammed Mahmoud Dawoud
Keyword(s):  
Brain Stem ◽  
Tissue Loss ◽  
Cerebellar Hemisphere ◽  
Stem Volume ◽  
Volume Loss ◽  
Neurological Disability ◽  
Disability Score ◽  
Brain Volume Loss ◽  
Significant Difference ◽  
Mri Volumetry

Abstract Background MRI is the method of choice in the diagnosis of MS as well as in monitoring the disease activity. MRI volumetry is used to assess whole or regional brain volume loss which reflects neurodegenerative aspect of the disease and plays an important role in all stages of disease. The aim of this work is to study MRI volumetry in the evaluation of cerebellum and brain stem volume loss in RRMS patients and its correlation with neurological disability score and number of relapses. Results Volumes of whole brainstem, medulla, and pons showed a significant decrease in RRMS cases compared to controls (p < 0.05). Brainstem volume had a mean volume of 22.17 and 25.09 cm3 in cases and controls, respectively. However, midbrain volume showed no significant difference between cases and controls (p = 0.134). Volume of left cerebellar cortex showed a significant decrease in RRMS cases compared to controls (p < 0.001). It had mean volumes of 81.64 and 92.14 ml in cases and controls, respectively, at left cerebellar hemisphere, while right cerebellar hemisphere cortex volumes were 80.37 and 91.97 ml in cases and controls, respectively. Cerebellar white matter showed no significant volume decrease in cases and controls. Conclusion Volumetric MR imaging is an important tool for quantifying the MS disease, assesses MS activity, progression, and tissue loss. The degree and the pattern of atrophy on MRI images correlate significantly with the neurological disability score and number of relapses.

Vitamin D Levels, APOE Allele, and MRI Volumetry Assessed by NeuroQuant in Norwegian Adults with Cognitive Symptoms

2021 ◽  
Vol 79 (1) ◽  
pp. 311-321
Author(s):  
Jelena Zugic Soares ◽  
Renate Pettersen ◽  
Jūratė Šaltytė Benth ◽  
Karin Persson ◽  
Carsten Strobel ◽  
...  
Keyword(s):  
Vitamin D ◽  
Late Onset ◽  
Apoe Genotype ◽  
Serum Levels ◽  
Grey Matter Volume ◽  
Cognitive Symptoms ◽  
Cross Sectional ◽  
Brain Volumes ◽  
Vitamin D Levels ◽  
Mri Volumetry

Background: Allele ɛ4 of the apolipoprotein (APOE ∈4) gene is the strongest known genetic risk factor for late-onset sporadic Alzheimer’s disease. A possible relationship between vitamin D and APOE is not yet clear. Objective: In this exploratory, cross-sectional study, we examined the association between serum levels of 25-hydroxyvitamin D [25(OH)D] and brain volumes and the associations of both serum levels of 25(OH)D and APOE polymorphism to brain volumes in 127 persons (mean age 66 years) with cognitive symptoms. Methods: All subjects were examined with fully automated software for MRI volumetry, NeuroQuant. Results: After adjustment for relevant covariates, higher serum 25(OH)D levels were associated with greater volumes of cortical gray matter on both left (p = 0.02) and right (p = 0.04) sides. When both 25(OH)D levels and APOE genotype were used as the main covariates, no significant associations were found between vitamin D level and brain volume in any of the 11 brain regions. In adjusted models, only homozygous but not heterozygous APOE ∈4 allele carriers had significantly larger inferior lateral ventricles (p = 0.003) and smaller hippocampal volume (p = 0.035) than those without ɛ4. Homozygous APOE ∈4 carriers also had significantly higher vitamin D levels (p = 0.009) compared to persons without the APOE ∈4 allele. Conclusion: Higher vitamin D levels might have a preserving effect on cortical grey matter volume.

scholarly journals Cerebellar atrophy is frequently associated with non-paraneoplastic sensory neuronopathy

2011 ◽  
Vol 69 (4) ◽  
pp. 602-606 ◽  
Author(s):  
Alfredo Damasceno ◽  
Marcondes C. França Jr ◽  
Fernando Cendes ◽  
Anamarli Nucci
Keyword(s):  
Cerebellar Atrophy ◽  
Anterior Lobe ◽  
Dorsal Root Ganglion Neurons ◽  
Volume Index ◽  
Cerebellar Volume ◽  
Truncal Ataxia ◽  
Immune Mediated ◽  
Mri Volumetry ◽  
And Gender ◽  
Ganglion Neurons

Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Despite the evidence of a defective proprioceptive sensory input in SN,the prominent gait and truncal ataxia raises the question of a concomitant involvement of the cerebellum. OBJECTIVE: To evaluate cerebellar atrophy in SN. METHOD: We analyzed MRI-based volumetry of anterior lobe (paleocerebellum) and total cerebellum in patients with non-paraneoplastic chronic SN and compared to age- and gender-matched controls. RESULTS: Cerebellum and anterior lobe MRI volumetry were performed in 20 patients and nine controls. Mean anterior lobe and cerebellar volume were not statistically different. Three patients (15%), however, had an abnormal anterior lobe and cerebellar volume index (values outside 2.5 standard deviations). One of them also had a specific atrophy of the anterior lobe. All these patients had infectious or dysimmune associated SN. CONCLUSION: Cerebellar atrophy is infrequently associated with SN, but can be found in some patients with SN related to infectious or immune mediated conditions. It can be more prominent in the anterior lobe and may contribute to the ataxia seen in these patients.

Thermo-Blood-Flowmetry, Microprocessor Processed Thermograms

1982 ◽  
pp. 222-227
Author(s):  
Iwao Fujimasa ◽  
Kou Imachi ◽  
Hitoshi Miyake ◽  
Masahiro Iwatani ◽  
Kazuhiko Atsumi
Keyword(s):  
Blood Flowmetry

scholarly journals Improving Accuracy of Brainstem MRI Volumetry: Effects of Age and Sex, and Normalization Strategies

2020 ◽  
Vol 14 ◽  
Author(s):  
Laura Sander ◽  
Antal Horvath ◽  
Simon Pezold ◽  
Simon Andermatt ◽  
Michael Amann ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Relative Standard Deviation ◽  
Healthy Subjects ◽  
Individual Variability ◽  
Intracranial Volume ◽  
Imaging Protocols ◽  
Relative Standard ◽  
Mri Volumetry ◽  
Improving Accuracy ◽  
Age And Sex

Background: Brainstem-mediated functions are impaired in neurodegenerative diseases and aging. Atrophy can be visualized by MRI. This study investigates extrinsic sources of brainstem volume variability, intrinsic sources of anatomical variability, and the influence of age and sex on the brainstem volumes in healthy subjects. We aimed to develop efficient normalization strategies to reduce the effects of intrinsic anatomic variability on brainstem volumetry.Methods: Brainstem segmentation was performed from MPRAGE data using our deep-learning-based brainstem segmentation algorithm MD-GRU. The extrinsic variability of brainstem volume assessments across scanners and protocols was investigated in two groups comprising 11 (median age 33.3 years, 7 women) and 22 healthy subjects (median age 27.6 years, 50% women) scanned twice and compared using Dice scores. Intrinsic anatomical inter-individual variability and age and sex effects on brainstem volumes were assessed in segmentations of 110 healthy subjects (median age 30.9 years, range 18–72 years, 53.6% women) acquired on 1.5T (45%) and 3T (55%) scanners. The association between brainstem volumes and predefined anatomical covariates was studied using Pearson correlations. Anatomical variables with associations of |r| &gt; 0.30 as well as the variables age and sex were used to construct normalization models using backward selection. The effect of the resulting normalization models was assessed by % relative standard deviation reduction and by comparing the inter-individual variability of the normalized brainstem volumes to the non-normalized values using paired t- tests with Bonferroni correction.Results: The extrinsic variability of brainstem volumetry across different field strengths and imaging protocols was low (Dice scores &gt; 0.94). Mean inter-individual variability/SD of total brainstem volumes was 9.8%/7.36. A normalization based on either total intracranial volume (TICV), TICV and age, or v-scale significantly reduced the inter-individual variability of total brainstem volumes compared to non-normalized volumes and similarly reduced the relative standard deviation by about 35%.Conclusion: The extrinsic variability of the novel brainstem segmentation method MD-GRU across different scanners and imaging protocols is very low. Anatomic inter-individual variability of brainstem volumes is substantial. This study presents efficient normalization models for variability reduction in brainstem volumetry in healthy subjects.

scholarly journals Automated MRI volumetry as a diagnostic tool for Alzheimer's disease: Validation of icobrain dm

2020 ◽  
Vol 26 ◽  
pp. 102243 ◽  
Author(s):  
Hanne Struyfs ◽  
Diana Maria Sima ◽  
Melissa Wittens ◽  
Annemie Ribbens ◽  
Nuno Pedrosa de Barros ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diagnostic Tool ◽  
Mri Volumetry

MRI volumetry of the hippocampus, amygdala, entorhinal cortex, and perirhinal cortex after status epilepticus

2000 ◽  
Vol 40 (2-3) ◽  
pp. 155-170 ◽  
Author(s):  
Tuuli Salmenperä ◽  
Reetta Kälviäinen ◽  
Kaarina Partanen ◽  
Esa Mervaala ◽  
Asla Pitkänen
Keyword(s):  
Status Epilepticus ◽  
Entorhinal Cortex ◽  
Perirhinal Cortex ◽  
Mri Volumetry

scholarly journals Quantitative MRI volumetry of the entorhinal cortex in temporal lobe epilepsy

Seizure ◽  
2000 ◽  
Vol 9 (3) ◽  
pp. 208-215 ◽  
Author(s):  
Tuuli Salmenperä ◽  
Reetta Kälviäinen ◽  
Kaarina Partanen ◽  
Asla Pitkänen
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Entorhinal Cortex ◽  
Temporal Lobe ◽  
Quantitative Mri ◽  
Mri Volumetry

Visual Grading Characteristics (VGC) Analysis of Diagnostic Image Quality for High Resolution 3 Tesla MRI Volumetry of the Olfactory Bulb

2011 ◽  
Vol 18 (5) ◽  
pp. 634-639 ◽  
Author(s):  
Hartmut Peter Burmeister ◽  
Pascal Andreas Thomas Baltzer ◽  
Constanze Möslein ◽  
Thomas Bitter ◽  
Hilmar Gudziol ◽  
...  
Keyword(s):  
High Resolution ◽  
Image Quality ◽  
Olfactory Bulb ◽  
3 Tesla ◽  
Diagnostic Image Quality ◽  
Diagnostic Image ◽  
Visual Grading ◽  
Mri Volumetry ◽  
3 Tesla Mri
Sign in / Sign up

Export Citation Format

Share Document