Depth-dependent proton magnetization transfer in articular cartilage

2005 ◽  
Vol 22 (2) ◽  
pp. 318-323 ◽  
Author(s):  
Ravinder R. Regatte ◽  
Sarma V.S. Akella ◽  
Ravinder Reddy
Keyword(s):  
Articular Cartilage ◽  
Magnetization Transfer ◽  
Proton Magnetization

Analysis of water-macromolecule proton magnetization transfer in articular cartilage

1993 ◽  
Vol 29 (2) ◽  
pp. 211-215 ◽  
Author(s):  
David K. Kim ◽  
Toni L. Ceckler ◽  
Vincent C. Hascall ◽  
Anthony Calabro ◽  
Robert S. Balaban
Keyword(s):  
Articular Cartilage ◽  
Magnetization Transfer ◽  
Proton Magnetization

Detecting Articular Cartilage and Meniscus Deformation Effects Using Magnetization Transfer Ultrashort Echo Time (MT-UTE) Modeling during Mechanical Load Application: Ex Vivo Feasibility Study

Cartilage ◽  
2020 ◽  
pp. 194760352097677
Author(s):  
Saeed Jerban ◽  
Akhil Kasibhatla ◽  
Yajun Ma ◽  
Mei Wu ◽  
Yanjun Chen ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Mechanical Load ◽  
Ex Vivo ◽  
Magnetization Transfer ◽  
Knee Joints ◽  
Loading Conditions ◽  
Ultrashort Echo Time ◽  
Short T2 ◽  
Echo Time ◽  
Magnetic Resonance Imaging Mri

Objective Ultrashort echo time (UTE) magnetic resonance imaging (MRI) sequences have improved imaging of short T2 musculoskeletal (MSK) tissues. UTE-MRI combined with magnetization transfer modeling (UTE-MT) has demonstrated robust assessment of MSK tissues. This study aimed to investigate the variation of UTE-MT measures under mechanical loading in tibiofemoral cartilage and meniscus of cadaveric knee joints. Design Fourteen knee joints from young ( n = 8, 42 ± 12 years old) and elderly ( n = 6, 89 ± 4 years old) donors were scanned on a 3-T scanner under 3 loading conditions: load = 300 N (Load1), load = 500 N (Load2), and load = 0 N (Unload). UTE-MT sequences were performed at each loading condition. Macromolecular proton fraction (MMF) was calculated from UTE-MT modeling. Wilcoxon rank sum test was used to examine the MRI data differences between loading conditions. Results For young donors, MMF increased in all grouped regions of interest (meniscus [M], femoral articular cartilage [FAC], tibial articular cartilage [TAC], articular cartilage regions covered by meniscus [AC-MC], and articular cartilage regions uncovered by meniscus [AC-UC]) when the load increased from 300 to 500 N. The increases in MMF were significant for M (13.3%, P < 0.01) and AC-MC (9.2%, P = 0.04). MMF decreased in all studied regions after unloading, which was significant only for AC-MC (−8.9%, P = 0.01). For elderly donors, MRI parameters did not show significant changes by loading or unloading. Conclusion This study highlights the potential of the UTE-MT modeling combined with knee loading in differentiating between normal and abnormal knees. Average tissue deformation effects were likely higher and more uniformly distributed in the joints of young donors compared with elderly donors.

scholarly journals Proton magnetization transfer effect in rat liver lactate

2002 ◽  
Vol 47 (5) ◽  
pp. 880-887 ◽  
Author(s):  
Tom Dresselaers ◽  
Niki Bergans ◽  
Paul Van Hecke ◽  
Florent Vanstapel
Keyword(s):  
Rat Liver ◽  
Magnetization Transfer ◽  
Transfer Effect ◽  
Proton Magnetization

Evidence of Multiple Ethanol Pools in the Brain: An in Vivo Proton Magnetization Transfer Study

1996 ◽  
Vol 20 (7) ◽  
pp. 1283-1288 ◽  
Author(s):  
Dieter J. Meyerhoff ◽  
William D. Rooney ◽  
Takaaki Tokumitsu ◽  
Michael W. Weiner
Keyword(s):  
Magnetization Transfer ◽  
The Brain ◽  
Proton Magnetization ◽  
Transfer Study

Water-Macromolecular Proton Magnetization Transfer in Infarcted Myocardium: A Method to Enhance Magnetic Resonance Image Contrast

1995 ◽  
Vol 33 (2) ◽  
pp. 178-184 ◽  
Author(s):  
Thomas D. Scholz ◽  
Robert F. Hoyt ◽  
John R. Deleonardis ◽  
Toni L. Ceckler ◽  
Robert S. Balaban
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Image ◽  
Magnetization Transfer ◽  
Image Contrast ◽  
Infarcted Myocardium ◽  
Proton Magnetization

scholarly journals In vivo observation of lactate methyl proton magnetization transfer in rat C6 glioma

1999 ◽  
Vol 41 (4) ◽  
pp. 676-685 ◽  
Author(s):  
Yanping Luo ◽  
Jan Rydzewski ◽  
Robin A. de Graaf ◽  
Rolf Gruetter ◽  
Michael Garwood ◽  
...  
Keyword(s):  
Magnetization Transfer ◽  
C6 Glioma ◽  
Methyl Proton ◽  
Proton Magnetization ◽  
Rat C6 Glioma
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