scholarly journals Effective blood signal suppression using double inversion-recovery and slice reordering for multislice fast spin-echo MRI and its application in simultaneous proton density and T2 weighted imaging

2004 ◽  
Vol 20 (5) ◽  
pp. 881-888 ◽  
Author(s):  
Hideto Kuribayashi ◽  
Jean J. Tessier ◽  
David R. Checkley ◽  
Yi-Xiang Wang ◽  
Leif Hultin ◽  
...  
Keyword(s):  
Spin Echo ◽  
Inversion Recovery ◽  
Double Inversion Recovery ◽  
Fast Spin Echo ◽  
Proton Density ◽  
Signal Suppression ◽  
Fast Spin

Detection of multiple sclerosis lesions in the cervical cord: which of the MAGNIMS ‘mandatory’ non-gadolinium enhanced sagittal sequences is optimal at 3T?

2021 ◽  
pp. 197140092110177
Author(s):  
Chian A Chang ◽  
Abigail L Chong ◽  
Ronil V Chandra ◽  
Ernest Butler ◽  
Deepa Rajendran ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Spin Echo ◽  
Inversion Recovery ◽  
Fast Spin Echo ◽  
Proton Density ◽  
Resonance Imaging ◽  
Short Tau Inversion Recovery ◽  
Fast Spin

Background and purpose The magnetic resonance imaging in multiple sclerosis consensus guidelines currently mandate three sagittal non-contrast enhanced sequences of T2-weighted fast spin echo, proton density-weighted fast spin echo and short tau inversion recovery; however, these particular three sequences have not previously been compared at 3T. This study compared T2-weighted fast spin echo, proton density-weighted fast spin echo, short tau inversion recovery as well as the double inversion recovery sequence for the sagittal detection of multiple sclerosis lesions in the cervical spinal cord at 3T. Methods Nineteen multiple sclerosis patients underwent magnetic resonance imaging with 3T sagittal T2-weighted fast spin echo, proton density-weighted fast spin echo, short tau inversion recovery and double inversion recovery between November 2012 and April 2013. Two neuroradiologists independently reviewed the images, and the number of lesions detected on each sequence was recorded. Lesion conspicuity was quantitatively assessed with the lesion-to-cord-contrast ratio and lesion contrast-to-noise ratio. The Wilcoxon signed rank test was performed for statistical analysis. Results Proton density-weighted fast spin echo and short tau inversion recovery detected 32% more lesions compared to T2-weighted fast spin echo, and 37% more lesions compared to double inversion recovery. The lesion-to-cord-contrast ratio was highest in short tau inversion recovery, while the lesion contrast-to-noise ratio was highest for proton density-weighted fast spin echo. Conclusions This study provides the necessary evidentiary support at 3T for the magnetic resonance imaging in multiple sclerosis spinal magnetic resonance imaging protocol consensus guidelines. At 3T sagittal proton density-weighted fast spin echo and short tau inversion recovery sequences allowed improved detection of cervical spinal cord multiple sclerosis lesions, compared to T2-weighted fast spin echo and three-dimensional double inversion recovery magnetic resonance imaging. Utilising T2-weighted fast spin echo alone at 3T is insufficient for lesion detection.

Value of Sagittal Fat-Suppressed Proton-Density Fast-Spin-Echo of the Knee Joint as a Limited Protocol in Evaluating Internal Knee Derangements

2011 ◽  
Vol 35 (5) ◽  
pp. 653-661 ◽  
Author(s):  
Nabil J. Khoury ◽  
Ziyad Mahfoud ◽  
Karim Z. Masrouha ◽  
Rayan Elkattah ◽  
Toni Assaad ◽  
...  
Keyword(s):  
Knee Joint ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
Proton Density ◽  
Fast Spin

scholarly journals High-resolution proton density weighted three-dimensional fast spin echo (3D-FSE) of the knee with IDEAL at 1.5 tesla: Comparison with 3D-FSE and 2D-FSE-initial experience

2011 ◽  
Vol 35 (2) ◽  
pp. 361-369 ◽  
Author(s):  
Colm J. McMahon ◽  
Ananth J. Madhuranthakam ◽  
Jim S. Wu ◽  
Corrie M. Yablon ◽  
Jesse L. Wei ◽  
...  
Keyword(s):  
High Resolution ◽  
Spin Echo ◽  
Three Dimensional ◽  
Fast Spin Echo ◽  
Proton Density ◽  
Initial Experience ◽  
Fast Spin

Improved Sensitivity of Bone Marrow Magnetic Resonance Imaging (BM-MRI) in Quantifying the Extent of Bone Marrow Involvement in Patients with Multiple Myeloma (MM).

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 4776-4776 ◽  
Author(s):  
Sikander Ailawadhi ◽  
Lyudmyla Derby ◽  
Kena C. Miller ◽  
Terry L. Mashtare ◽  
Gregory Wilding ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Correlation Coefficient ◽  
Spin Echo ◽  
Staging System ◽  
Inversion Recovery ◽  
Fast Spin Echo ◽  
Statistical Relationship ◽  
Spearman Correlation ◽  
Fast Spin

Abstract Background: Traditionally, bone marrow aspirate/biopsy (BM-Bx) has been used for diagnosis and quantification of the extent of disease as well as response to therapy in MM patients. This information is used to make decision for treatment initiation. Since MM is not a contiguous disease, marrow involvement can be patchy and BM-Bx may be misleading in assessing the true extent of the disease. BM-MRI is a non-invasive technique that can evaluate a large amount of marrow for tumor infiltration. We prospectively investigated the sensitivity of BM-MRI and compared its results with those obtained by BM-Bx as well as with the clinical stage of disease. Methods: All patients with the diagnosis of MM who had BM-MRI at our center were evaluable. Patients must have received a BM-Bx within 4 weeks of the BM-MRI. In these patients sagittal T1 and fast spin echo inversion recovery sequences of the cervical, thoracic and lumbosacral spine and coronal T1 and fast spin echo inversion recovery sequences of the sacrum and pelvic bones were reviewed on the MRI. Durie-Salmon (DS) staging criteria were used for correlation. To study the statistical relationship between pairs of ordinal variables the test corresponding to the Spearman correlation was used. To study the statistical relationship between nominal and ordinal variables, the Wilcoxon or Kruskal-Wallis test was used. A 0.05 nominal significance level was used in all testing. Following staging system was defined for evaluation of the involvement of the marrow by BM-MRI: A (0%), B (< 10%), C (10%–25%), D (26%–50%), E (> 50%). Results of this were then compared with the extent of involvement reported on histological evaluation of the BM-Bx. Results: A total of 50 patients (23 females and 27 males) were identified. Median age was 61.5 years (range 35–82 years) with 23 (46%) having stage IIIA disease. As per the staging system defined above, 6%, 10%, 10%, 22% and 52% of the patients had categories A, B, C, D and E involvement as per BM-MRI, respectively. Similarly, involvement observed on the BM-Bx was 8%, 24%, 22%, 16% and 30%, respectively. Categories of marrow involvement on BM-Bx and BM-MRI were concordant in 23 (46%) and discordant in 27 (54%) patients. Of the patients that showed discordance, 89% had a more extensive BM involvement detected by the BM-MRI and 11% had a higher reading on BM-Bx. The estimated Spearman correlation coefficient between MRI involvement and MM stage was 0.4849 (95% CI; 0.2494, 0.7205), showing a significant association between BM-MRI involvement and MM stage (p =0.0002). The estimated Spearman correlation coefficient between BM-Bx involvement and MM stage was 0.1775 (95% CI; −0.1406, 0.4956), showing no significant association between BM-Bx involvement and MM stage (p = 0.2764). Conclusions: We demonstrate for the first time that BM-MRI is a more sensitive technique to assess the true disease burden in MM and is significantly better than BM-Bx. We also observe that the extent of marrow infiltration noted on the BM-MRI correlates significantly with other prognostic characteristics like DS stage. Based on this observation we recommend that BM-MRI should be considered as part of the pre-treatment evaluation of patients with multiple myeloma.

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