scholarly journals Imaging of the articular cartilage in osteoarthritis of the knee joint: 3D spatial-spectral spoiled gradient-echo vs. fat-suppressed 3D spoiled gradient-echo MR imaging

2003 ◽  
Vol 18 (1) ◽  
pp. 66-71 ◽  
Author(s):  
Hiroshi Yoshioka ◽  
Marcus Alley ◽  
Daniel Steines ◽  
Kathryn Stevens ◽  
Erika Rubesova ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Mr Imaging ◽  
Knee Joint ◽  
Osteoarthritis Of The Knee ◽  
Gradient Echo ◽  
Spoiled Gradient Echo

scholarly journals MORPHOLOGICAL CHANGES IN THE TISSUES OF THE RABBIT KNEE JOINT DUE TO EXPERIMENTAL OSTEOARTHRITIS AFTER THE USE OF MESENCHYMAL STEM CELLS

2021 ◽  
Vol 359 (58) ◽  
pp. 13-24
Author(s):  
Nikolai MALYUK ◽  
◽  
Yuliia DEMIANTSEVA ◽  
Yuriy KHARKEVYCH ◽  
Roman BOKOTKO ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Articular Cartilage ◽  
Knee Joint ◽  
Traditional Method ◽  
Control Group ◽  
Osteoarthritis Of The Knee ◽  
Allogeneic Bone ◽  
Experimental Osteoarthritis ◽  
Experimental Group

The purpose of the study was to investigate the regenerative processes in the knee joint of rabbits with experimental osteoarthritis after using of allogeneic bone marrow stem cells and a traditional treatment with the non-steroidal anti-inflammatory drug Meloxicam. For the experiment were used 27 male California rabbits (males). Three groups of animals were formed: a control group; the first experimental group treated by the traditional method; the second experimental group treated with allogeneic mesenchymal stem cells (MSC). Animals in the three groups were subjected to osteoarthritis of the knee joint by double injection of 3.44% retinol acetate into the joint cavity at a dose of 1 ml at intervals of 7 days. Tissue from the affected site was sampled for histological examination at 7, 14 and 28 days. The histological sections were stained with haematoxylin-eosin and examined under a microscope. It has been established that intra-articular administration of 3.5 × 106 cells of allogeneic MSCs in experimental osteoarthritis contributes to the restoration of the superficial layer of cartilage, as evidenced by the formation of columns of chondrocytes in the middle layer of articular cartilage and the appearance of isogenic groups of cartilage cells with basophilic cytoplasm in the matrix, uniform articular surface. The use of the traditional method of treating rabbits using the drug Meloxicam is accompanied by incomplete chondrogenesis: part of the chondrocytes is localized in typical chambers, in some cases chondrocyte chambers did not differentiate; articular cartilage had unequal thickness, cell placement was uneven.

T1-weighted spoiled gradient-echo MR imaging of focal hepatic lesion: comparison of in-phase vs opposed-phase pulse sequence

1997 ◽  
Vol 7 (7) ◽  
pp. 1048-1053 ◽  
Author(s):  
P. Soyer ◽  
Y. Rondeau ◽  
A.-C. Dufresne ◽  
L. Spelle ◽  
E. Somveille ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Pulse Sequence ◽  
Hepatic Lesion ◽  
Gradient Echo ◽  
Focal Hepatic Lesion ◽  
Spoiled Gradient Echo

scholarly journals Age- and Occupation-Based Public Health Considerations Related to Osteoarthritis of the Knee Joint: A Cadaveric Study

Cartilage ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 238-244 ◽  
Author(s):  
Jessica Immonen ◽  
Chris Siefring
Keyword(s):  
Articular Cartilage ◽  
Knee Joint ◽  
Tibial Plateau ◽  
Disease Onset ◽  
Adult Life ◽  
Clinical History ◽  
Cartilage Degeneration ◽  
Time Frame ◽  
Osteoarthritis Of The Knee ◽  
Occupational Class

Objective Osteoarthritis (OA) literature makes minimal suggestion regarding age of disease onset or preventative strategies to reduce risk for onset in various populations. In 2005, the Centers for Disease Control and Prevention estimated that 33.6% of Americans 65+ years old were affected by OA; this cadaveric analysis suggests this is largely underestimated. The objective of this assessment is to identify at-risk populations for OA in the knee joint and make recommendations to prevent or delay disease onset. Design Morphometric analyses of the articular cartilage of the tibial plateau were performed on cadaver specimens using Image Pro software on 3 age populations and surface area measurements for articular cartilage degradation were compared with donors’ reported ages, clinical histories, and occupations. Results Data showed that by the seventh decade of life, when patients are in their 60s, articular cartilage degeneration on the tibial plateau had commenced in 100% of specimen. All “homemakers” displayed above-average medial tibial plateau degeneration (32.33% ± 24.85%) for their age group while simultaneously reporting pathologies in their clinical history that encourage a sedentary lifestyle. Conclusions This assessment identifies an occupational class with a propensity to develop disease and also identifies a more realistic time frame than previous advisory committees have produced regarding age of disease onset and initiation of preventative measures. It is recommended that strengthening of the hip abductors and the musculature supporting the knee commence early in adult life to avoid valgus collapse and shearing at the knee joint.

Crohn Disease with Endoscopic Correlation: Single-Shot Fast Spin-Echo and Gadolinium-enhanced Fat-suppressed Spoiled Gradient-Echo MR Imaging

Radiology ◽  
2002 ◽  
Vol 222 (3) ◽  
pp. 652-660 ◽  
Author(s):  
Russell N. Low ◽  
Christopher P. Sebrechts ◽  
Douglas A. Politoske ◽  
Michael T. Bennett ◽  
Sergio Flores ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Crohn Disease ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
Single Shot ◽  
Gradient Echo ◽  
Endoscopic Correlation ◽  
Fast Spin ◽  
Spoiled Gradient Echo

scholarly journals Comparison of 1.5- and 3.0-T MR Imaging for Evaluating the Articular Cartilage of the Knee Joint

Radiology ◽  
2009 ◽  
Vol 250 (3) ◽  
pp. 839-848 ◽  
Author(s):  
Richard Kijowski ◽  
Donna G. Blankenbaker ◽  
Kirkland W. Davis ◽  
Kazuhiko Shinki ◽  
Lee D. Kaplan ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Mr Imaging ◽  
Knee Joint ◽  
3.0 T
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