Investigation of the interaction between split aptamer and vascular endothelial growth factor 165 using single molecule force spectroscopy

2020 ◽  
Vol 33 (5) ◽  
Author(s):  
Shaoyuan Li ◽  
Yan Zheng ◽  
Yaqin Liu ◽  
Xiuhua Geng ◽  
Xiaofeng Liu ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Single Molecule ◽  
Force Spectroscopy ◽  
Vascular Endothelial ◽  
Single Molecule Force Spectroscopy ◽  
Endothelial Growth Factor

Interaction of vascular endothelial growth factor and heparin quantified by single molecule force spectroscopy

Nanoscale ◽  
2020 ◽  
Vol 12 (22) ◽  
pp. 11927-11935
Author(s):  
Miaomiao Zhang ◽  
Ying Liu ◽  
Fengchao Cui ◽  
Christian Rankl ◽  
Juan Qin ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Vascular Endothelial Growth Factor ◽  
Molecular Dynamics Simulation ◽  
Growth Factor ◽  
Single Molecule ◽  
Force Spectroscopy ◽  
Dynamics Simulation ◽  
Vascular Endothelial ◽  
Single Molecule Force Spectroscopy ◽  
Endothelial Growth Factor

The interaction of VEGF165 and heparin was studied quantitatively and visually utilizing single molecule force spectroscopy and molecular dynamics simulation.

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