scholarly journals Adenosine kinase deficiency presenting with tortuous cervical arteries: A risk factor for recurrent stroke

JIMD Reports ◽  
2021 ◽  
Author(s):  
José A. Paz ◽  
Emilia K. Embiruçu ◽  
Clarissa Bueno ◽  
Rafaela C. C. L. Ferreira ◽  
Fernanda S. Oliveira ◽  
...  
Keyword(s):  
Risk Factor ◽  
Recurrent Stroke ◽  
Adenosine Kinase

Impact of Baseline Features and Risk Factor Control on Cognitive Function in the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Trial

2019 ◽  
Vol 47 (1-2) ◽  
pp. 24-31 ◽  
Author(s):  
Tanya N. Turan ◽  
Sami Al Kasab ◽  
Alison Smock ◽  
George Cotsonis ◽  
David Bachman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Medical Management ◽  
Physical Inactivity ◽  
Recurrent Stroke ◽  
Older Age ◽  
Aggressive Medical Management

Background: Cerebrovascular disease is an important cause of cognitive impairment. The aim of this study is to report the relationship between cognitive function and risk factors at baseline and during follow-up in the Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis (SAMMPRIS) trial. Methods: Subjects in the SAMMPRIS trial were included in this study. In order to have an assessment of cognitive function independent of stroke, patients with a stroke as a qualifying event whose deficits included aphasia or neglect were excluded from these analyses as were those with a cerebrovascular event during follow-up. The Montreal Cognitive Assessment (MoCA) score was used to assess cognitive impairment at baseline, 4 months, 12 months and closeout. Cognitive impairment was defined as MoCA < 26. A multivariate analysis was performed to determine what risk factors were independent predictors of cognitive function at baseline, 12 months and closeout. Among patients randomized to aggressive medical management only, the percentage of patients with cognitive impairment was compared between patients in versus out of target for each risk factor at 12 months and closeout. Results: Of the 451 patients in SAMMPRIS, 371 patients met the inclusion criteria. MoCA < 26 was present in 55% at baseline. Older age and physical inactivity were associated with cognitive impairment at baseline. Older age, non-white race, lower baseline body mass index, and baseline cognitive impairment were associated with cognitive impairment at 12 months. In the aggressive medical management group, at 12 months, physical inactivity during follow-up was the strongest risk factor associated with cognitive impairment. Conclusion: Cognitive impairment is common in patients with severe symptomatic intracranial atherosclerosis. Physical inactivity at baseline and during follow-up is a strong predictor of cognitive impairment.

scholarly journals Long term clinical outcomes of patients with ischemic stroke in primary care – a 9-year retrospective study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jinghao Han ◽  
Yue Kwan Choi ◽  
Wing Kit Leung ◽  
Ming Tung Hui ◽  
Maria Kwan Wa Leung
Keyword(s):  
Blood Pressure ◽  
Primary Care ◽  
Risk Factor ◽  
Ischemic Stroke ◽  
Diastolic Blood Pressure ◽  
Recurrent Stroke ◽  
Stroke Patients ◽  
All Cause Mortality

Abstract Background We aim to document the long-term outcomes of ischemic stroke patients and explore the potential risk factors for recurrent cardiovascular events and all-cause mortality in primary care. Methods A retrospective cohort study performed at two general out-patient clinics (GOPCs) under Hospital Authority (HA) in Hong Kong (HK). Ischemic stroke patients with at least two consecutive follow-up visits during the recruitment period (1/1–30/6/2010) were included. Patients were followed up regularly till the date of recurrent stroke, cardiovascular event, death or 31/12/2018. The primary outcome was the occurrence of recurrent cerebrovascular event including transient ischemic stroke (TIA), ischemic stroke or hemorrhagic stroke. The secondary outcomes were all-cause mortality and coronary artery disease (CAD). We fit cox proportional hazard model adjusting death as competing risk factor to estimate the cause-specific hazard ratio (csHR). Results A total of 466 patients (mean age, 71.5 years) were included. During a median follow-up period of 8.7 years, 158 patients (33.9%) died. Eighty patients (17.2%) had recurrent stroke and 57 (12.2%) patients developed CAD. Age was an independent risk factor for recurrent stroke, CAD and death. Statin therapy at baseline had a protective effect for recurrent stroke (csHR = 0.476; 95% confidence interval [CI] 0.285–0.796, P = 0.005) after adjusting death as a competing risk factor and all-cause mortality (HR = 0.693, 95% CI 0.486–0.968, P = 0.043). In addition, female sex, antiplatelet and a higher diastolic blood pressure (DBP) at baseline were also independent predictors for survival. Conclusions Long term prognosis of ischemic stroke patients in primary care is favorable. Use of statin was associated with a significant decrease in stroke recurrence and mortality. Patients who died had a significant lower DBP at baseline, highlighted the need to consider both systolic and diastolic blood pressure in our daily practice.

scholarly journals The Risk Factor of Recurrence Stroke Among Stroke and Transient Ischemic Attack Patients in Indonesia

2019 ◽  
Author(s):  
Listian Prisilia Rahayu ◽  
Serlina . ◽  
Diwa Agus Sudrajat ◽  
Gina Nurdina ◽  
Elis Nurhayati Agustina ◽  
...  
Keyword(s):  
Risk Factor ◽  
Recurrent Stroke ◽  
Descriptive Study ◽  
Neurological Deficits ◽  
Dominant Factor ◽  
Stroke Recurrence ◽  
Cardiovascular Disorders ◽  
Cross Sectional ◽  
Ischemic Attack ◽  
The Brain

Background: Stroke described as a disruption of blood flow in the brain which can lead to brain malfunction, neurological deficits, and even death. Although with good management in acute period, the incidence of recurrent stroke still increasing every year. Objectives: This study aimed to determine the dominant risk factor of stroke recurrence. Methods: This study was a cross sectional descriptive study with 274 strokes patients as samples. The samples were recruited from one of general hospital specialize in neurology disorders in Jakarta, Indonesia. Results: The result indicated a significant correlation between cardiovascular disorders, cholesterol, and activity with incidence of stroke recurrent (p<0.05). The dominant risk factor in this study was obesity event (OR = 0.616) Conclusion: Besides the dominant factor, there were 3 factors that significantly affect stroke recurrence; cardiovascular disorders, hypercholesterolemia, and physical activity. Nurses should be more aware that some patients may still have risk factors of stroke recurrence even they have discharged from hospital. With some efforts like health education and controlling the factors can help to reduce the risk of stroke recurrence.  

scholarly journals SICKLE CELL ANAEMIA: A MODIFIABLE RISK FACTOR OF STROKE AMONG YOUNG BLACK ADULTS: A REVIEW OF THE CURRENT LITERATURE

2018 ◽  
Vol 6 (4) ◽  
Author(s):  
Yunusa EU ◽  
Bakare AT ◽  
Shagari GB ◽  
Abubakar AM ◽  
Sharhabila Y ◽  
...  
Keyword(s):  
Young Adults ◽  
Risk Factor ◽  
Incidence Rate ◽  
Sickle Cell ◽  
Sickle Cell Anaemia ◽  
Recurrent Stroke ◽  
Resource Limited ◽  
Almost All ◽  
Risk Factor Prevention ◽  
And Control

Incidence of stroke among young adults between the age brackets of 20 to 54 years of age has increased significantly; suggesting that stroke in the young is on the rise. In a community based retrospective study, the proportion of all strokes that occurred in young adults increased from 13% to 19% over one decade. Additionally, the incidence rate of stroke among blacks increased from 83 per 100,000 to 128 per 100,000, as compared to whites in whom, the incidence rate increased from 26 to 48 per 100,000. Therefore, aggressive risk factor control particularly among blacks is extraordinarily important. Furthermore, almost all the conventional stroke risk factors for incident stroke, proved to also be a risk factor for recurrent stroke, suggesting that equal vigilance for risk-factor prevention and control is appropriate for primary and secondary stroke prevention. This review tends to shed some light on the role of sickle cell anaemia in the pathophysiologic mechanism of stroke hoping that, the review would not only create more awareness on stroke management but would inform policy-makers on the urgency and mechanism required for cheap and affordable treatment of acute stroke among sickle cell anaemia patient, particularly in resource limited countries like Nigeria. It would also be a useful resource material for regional, national and international bodies that are involved in the management of patients with stroke.

MULTIGENIC THROMBOPHILIAAS A RISK FACTOR OF RECURRENT STROKE

2015 ◽  
Vol 19 (4) ◽  
pp. 44
Author(s):  
L. V. Lukyanchikova ◽  
L. V. Belskaya ◽  
D. F. Khairutdinova ◽  
E. I. Lusanova ◽  
D. V. Popov ◽  
...  
Keyword(s):  
Risk Factor ◽  
Recurrent Stroke

scholarly journals The Risk Factor of Recurrence Stroke among Stroke and Transient Ischemic Attack Patients in Indonesia

2019 ◽  
Author(s):  
Listian Prisilia Rahayu ◽  
Diwa Agus Sudrajat ◽  
Gina Nurdina ◽  
Elis Nurhayati Agustina ◽  
Tri Antika Rizki Kusuma Putri
Keyword(s):  
Risk Factor ◽  
Recurrent Stroke ◽  
Descriptive Study ◽  
Neurological Deficits ◽  
Dominant Factor ◽  
Stroke Recurrence ◽  
Cardiovascular Disorders ◽  
Cross Sectional ◽  
Ischemic Attack ◽  
The Brain

Background:Stroke described as a disruption of blood flow in the brain which can lead to brain malfunction, neurological deficits, and even death. Although with good managementin acute period, the incidence of recurrent stroke still increasing every year. Objectives: This study aimed to determine the dominant risk factorof stroke recurrence. Methods: This study was a cross sectional descriptive study with 274 strokes patients as samples. The samples were recruited from one of general hospital specialize in neurology disorders in Jakarta, Indonesia. Results: The result indicated a significant correlation betweencardiovascular disorders, cholesterol, and activity withincidence of stroke recurrent (p<0.05). The dominant risk factor in this study wasobesity event (OR = 0.616). Conclusion: Besides the dominant factor, there were 3 factors that significantly affectstroke recurrence;cardiovascular disorders, hypercholesterolemia, and physical activity.Nurses should be more aware that some patients may still have risk factors of stroke recurrence even they have discharged from hospital. With some efforts like health education and controlling the factors can help to reduce the risk of stroke recurrence.  

Aphasia and Atherosclerosis

2016 ◽  
Author(s):  
Ji Y. Chong ◽  
Michael P. Lerario
Keyword(s):  
Risk Factor ◽  
High Risk ◽  
Antiplatelet Therapy ◽  
Treatment Regimen ◽  
Stroke Prevention ◽  
Recurrent Stroke ◽  
High Morbidity ◽  
High Grade ◽  
Intracranial Atherosclerosis ◽  
Risk Factor Control

High-grade intracranial atherosclerosis is associated with a high risk of recurrent stroke. Medical therapy with antiplatelet therapy and aggressive risk factor control is the preferred treatment regimen for stroke prevention in patients with intracranial atherosclerosis. Current stenting techniques are associated with high morbidity and mortality.

Abstract WP355: Recurrent Stroke is an Independent Risk Factor for Ischemic Stroke Prognosis

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Haiqiang Qin ◽  
Gaifeng Liu ◽  
Penglian Wang ◽  
Runhua Zhang ◽  
Miaoxin Yu ◽  
...  
Keyword(s):  
Risk Factor ◽  
Ischemic Stroke ◽  
Poor Prognosis ◽  
Independent Risk Factor ◽  
Recurrent Stroke ◽  
Multivariable Analysis ◽  
Stroke Registry ◽  
Risk Of Death ◽  
Composite Events ◽  
Worse Prognosis

Introduction: Recurrent ischemic stroke is more likely to have a worse prognosis. However, it is little known whether recurrent stroke is an independent risk factor for poor prognosis. We aim to investigate the difference of mortality and recurrent rate of first ever and recurrent ischemic strokes, as well as to explore the potential reasons. Method: We analyzed patients with ischemic stroke enrolled in the China National Stroke Registry which was a nationwide, multicenter, and prospective registry of consecutive patients with acute cerebrovascular events from 2007 to 2008. Date including hypertension, diabetes mellitus, hyperlipidemia, heart disease, etc. were obtained from paper-based registry forms. Multivariable analysis using logistic regression was performed to assess the risk of worse prognosis of recurrent ischemic stroke compared to first-ever stroke. Result: A total of 8 181 patients with first-ever stroke and 4 234 patients with recurrent stroke were enrolled in the study. For patients with first-ever stroke, the mortality, recurrence, composite Events(modified Rankin Scale=3-6, which means death or disability) rate is 7.2%, 10.3%, 22.6%, respectively at 3-month; and 9.0%, 13.0%, 29.0% at 6-month; as well as 11.4%, 14.7%, 28.5% at 1 year, respectively. For patients with recurrent stroke, the mortality, recurrence, composite events rate is 10.5%, 16.1%, 30.8% respectively at 3-month, and 13.9%, 20.3%, 41.7% at 6-month, as well as 17.3%, 23.6%, 42.1% at 1 year, respectively. Multivariable analysis showed that patients with recurrent stroke had a higher risk of death, recurrence and disability at 3-month, 6 month and 1 year (table 1). Conclusion: After adjusting for multiple risk factors, recurrent stroke is still an independent risk factor for poor prognosis of ischemic stroke, which further emphasizes the importance of secondary prevention of ischemic stroke, and the specific causes need to be furtherly investigated.

scholarly journals Hypertension Risk Factor Control Effort In Post Stroke Patients

2022 ◽  
Vol 4 (2) ◽  
pp. 639-644
Author(s):  
Yosi Suryarinilsih ◽  
Hendri Budi ◽  
Netti Netti ◽  
Wiwi Sartika
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Health Education ◽  
Stroke Risk ◽  
Recurrent Stroke ◽  
Stroke Patients ◽  
Post Stroke ◽  
Stroke Risk Factors ◽  
Breathing Exercises ◽  
Significant Difference

Post-stroke patients have risk factors for recurrent stroke. The main risk factor is hypertension. The purpose of this community service activity is to improve the ability of the community, especially post-stroke patients, to control hypertension as a risk factor for recurrent stroke through identification of risk factors, health education and the application of light activity and deep breathing exercises. Before education is given, post-stroke patients and their families are given prestest first and after education, posttest returns to evaluate the patient's understanding. The results of the activity, there was a significant difference between the knowledge before and after being given education to post-stroke patients and their families with p value <0.05. To the head of the room and the neuroscientific nurse, dr. M. Djamil Padang can continue the activity of identifying recurrent stroke risk factors and health education related to control of recurrent stroke risk factors in post-stroke patients by involving the Health Promotion (Promkes) department of Dr. M. Djamil Padang.

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