scholarly journals Low risk of neurodevelopmental impairment among perinatally acquired HIV ‐infected preschool children who received early antiretroviral treatment in Thailand

2019 ◽  
Vol 22 (4) ◽  
pp. e25278 ◽  
Author(s):  
Watsamon Jantarabenjakul ◽  
Weerasak Chonchaiya ◽  
Thanyawee Puthanakit ◽  
Tuangtip Theerawit ◽  
Jesdaporn Payapanon ◽  
...  
Keyword(s):  
Preschool Children ◽  
Antiretroviral Treatment ◽  
Low Risk ◽  
Neurodevelopmental Impairment ◽  
Perinatally Acquired ◽  
Early Antiretroviral Treatment

scholarly journals Early antiretroviral treatment prevents the development of central nervous system abnormalities in simian immunodeficiency virus-infected rhesus monkeys

AIDS ◽  
2009 ◽  
Vol 23 (10) ◽  
pp. 1187-1195 ◽  
Author(s):  
Maria Cecilia G Marcondes ◽  
Claudia Flynn ◽  
Salvador Huitron-Rezendiz ◽  
Debbie D Watry ◽  
Michelle Zandonatti ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Simian Immunodeficiency Virus ◽  
Rhesus Monkeys ◽  
Antiretroviral Treatment ◽  
Immunodeficiency Virus ◽  
Early Antiretroviral Treatment

scholarly journals French HIV Experts on Early Antiretroviral Treatment for Prevention

2013 ◽  
Vol 13 (2) ◽  
pp. 160-169 ◽  
Author(s):  
Bertrand Lebouché ◽  
Kim Engler ◽  
Joseph J. Lévy ◽  
Norbert Gilmore ◽  
Bruno Spire ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Early Antiretroviral Treatment

scholarly journals Association of HIV diversity and virologic outcomes in early antiretroviral treatment: HPTN 052

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177281 ◽  
Author(s):  
Philip J. Palumbo ◽  
Ethan A. Wilson ◽  
Estelle Piwowar-Manning ◽  
Marybeth McCauley ◽  
Theresa Gamble ◽  
...  
Keyword(s):  
Antiretroviral Treatment ◽  
Hiv Diversity ◽  
Early Antiretroviral Treatment

scholarly journals Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 133
Author(s):  
Domenico M. Romeo ◽  
Martina Ricci ◽  
Federica Mirra ◽  
Ilaria Venezia ◽  
Maria Mallardi ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Preschool Age ◽  
Cognitive Outcomes ◽  
Low Risk ◽  
Neurological Deficits ◽  
Cognitive Assessments ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Normal Ranges ◽  
Neurodevelopmental Impairment

Background and Objectives: Preterm infants are at higher risk of neurodevelopmental impairment both at preschool and school ages, even in the absence of major neurological deficits. The early identification of children at risk is essential for early intervention with rehabilitation to optimize potential outcomes during school years. The aim of our study is to assess cognitive outcomes at preschool age in a cohort of low-risk very preterm infants, previously studied at 12 and 24 months using the Griffiths scales. Materials and Methods: Sixty-six low-risk very preterm infants born at a gestational age of <32 weeks were assessed at 12 and 24 months corrected age using the Griffiths Mental Development Scales (second edition) and at preschool age with the Wechsler Preschool and Primary Scales of Intelligence (third edition) (WPPSI-III). Results: At 12 and 24 months and at preschool age, low-risk very preterm infants showed scores within normal ranges with similar scores in males and females. A statistically significant correlation was observed in the general developmental quotient between 12 and 24 months; a further significant correlation was observed between the early cognitive assessments and those performed at preschool age, with a better correlation using the assessments at 24 months. Conclusion: The present study showed a favourable trajectory of cognitive development in low-risk very preterm infants, from 12 months to preschool age.

Excessive Weight Gain Associated With Dolutegravir Initiation in a 10-Year-Old Female With Perinatally Acquired Human Immunodeficiency Virus: A Case Report and Review of the Literature

2020 ◽  
Author(s):  
J Li ◽  
E H Yusuf ◽  
A L Agwu
Keyword(s):  
Human Immunodeficiency Virus ◽  
Weight Gain ◽  
Antiretroviral Treatment ◽  
Review Of The Literature ◽  
Excessive Weight Gain ◽  
Excessive Weight ◽  
Immunodeficiency Virus ◽  
Perinatally Acquired ◽  
Short And Long Term

Abstract Children with perinatally acquired human immunodeficiency virus (PHIV) face a lifetime of combination antiretroviral treatment that often includes dolutegravir (DTG). DTG, an integrase strand inhibitor that has been linked to weight gain in adults, is increasingly being used in children. Understanding its potential short- and long-term sequelae in children is critically important. We report a case of excessive weight gain in a child with PHIV on DTG and provide a brief literature review.

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