scholarly journals The influence of age-associated comorbidities on responses to combination antiretroviral therapy in older people living with HIV

2019 ◽  
Vol 22 (2) ◽  
pp. e25228 ◽  
Author(s):  
Mi Young Ahn ◽  
Awachana Jiamsakul ◽  
Suwimon Khusuwan ◽  
Vohith Khol ◽  
Thuy T Pham ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Older People ◽  
People Living With Hiv ◽  
Combination Antiretroviral Therapy ◽  
Living With Hiv

scholarly journals Mortality and causes of death in people living with HIV in the era of combination antiretroviral therapy compared with the general population in Japan

AIDS ◽  
2020 ◽  
Vol 34 (6) ◽  
pp. 913-921 ◽  
Author(s):  
Takeshi Nishijima ◽  
Yosuke Inaba ◽  
Yohei Kawasaki ◽  
Kunihisa Tsukada ◽  
Katsuji Teruya ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
General Population ◽  
Causes Of Death ◽  
People Living With Hiv ◽  
Combination Antiretroviral Therapy ◽  
Living With Hiv

The Impact of Continuation or Initiation of Combination Antiretroviral Therapy in People Living with HIV Presenting with Acute Septic Shock

2018 ◽  
Vol 32 (9) ◽  
pp. 337-339
Author(s):  
Christopher Polk ◽  
Sam Webb ◽  
Nigel Rozario ◽  
Charity G. Moore ◽  
Alan C. Heffner ◽  
...  
Keyword(s):  
Septic Shock ◽  
Antiretroviral Therapy ◽  
People Living With Hiv ◽  
Combination Antiretroviral Therapy ◽  
Living With Hiv ◽  
The Impact

Efavirenz use and neurocognitive performance among older people living with HIV who were on antiretroviral therapy

AIDS Care ◽  
2019 ◽  
Vol 32 (1) ◽  
pp. 12-20
Author(s):  
Pei Qin ◽  
Jianmei He ◽  
Zixin Wang ◽  
Xi Chen ◽  
Jinghua Li ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Older People ◽  
People Living With Hiv ◽  
Neurocognitive Performance ◽  
Living With Hiv

scholarly journals Causes of hospitalisation among a cohort of people with HIV from a London centre followed from 2011 to 2018

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sophia M. Rein ◽  
Fiona C. Lampe ◽  
Clinton Chaloner ◽  
Adam Stafford ◽  
Alison J. Rodger ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Infectious Diseases ◽  
Sexual Transmission ◽  
Transmission Risk ◽  
People Living With Hiv ◽  
Combination Antiretroviral Therapy ◽  
Icd 10 ◽  
The Uk ◽  
Living With Hiv ◽  
Record Review

Abstract Background We describe the spectrum of ICD-10 classified causes for hospitalisations occurring between 2011 and 2018 in a cohort of people living with HIV (PLHIV). Methods This sub-study includes 798 PLHIV participating in the Antiretroviral, Sexual Transmission Risk and Attitudes (ASTRA) questionnaire study who were recruited from a large London centre. A medical record review identified the occurrence and causes of hospitalisation from the date of questionnaire completion (February–December 2011) until 1 June 2018. Up to five causes were classified by an HIV clinician using the ICD-10 system. Results There were 274 hospitalisations in 153 people (rate = 5.8/100 person-years; 95% CI: 5.1, 6.5). Causes were wide-ranging; the most common were circulatory (16.8%), digestive (13.1%), respiratory (11.7%), infectious diseases (11.0%), injury/poisoning (10.6%), genitourinary diseases (9.9%) and neoplasms (9.1%). A tenth (27/274) of hospitalisations were related to at least one AIDS-defining illness. Median duration of hospitalisation was 5 days (IQR 2–9). At the time of hospitalisation, median CD4 count was high (510 cells/μl; IQR: 315–739), while median CD4 nadir was relatively low (113 cells/μl; IQR: 40–239). At admission, half of individuals (51%) had a previous AIDS-defining illness and 21% had viral load > 50 copies/ml. Individuals admitted for infectious diseases were particularly likely to have unfavourable HIV-related clinical characteristics (low CD4, viral non-suppression, not on antiretroviral therapy (ART), previous AIDS). Conclusions In the modern combination antiretroviral therapy era, the spectrum of causes of hospitalisation in PLHIV in the UK is wide-ranging, highlighting the importance of holistic care for PLHIV, including prevention, early detection and treatment of comorbidities.

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