Synthesis and Biological Activity of Novel Ethyl Esters of 4-R-6,8-Dimethyl-1-oxo-1,2-dyhidropyrrolo[1,2-d][1,2,4]triazine-7-carboxylic Acids

2015 ◽  
Vol 53 (2) ◽  
pp. 421-428 ◽  
Author(s):  
Valeriia Astakhina ◽  
Maxim Voievudskyi ◽  
Olexander Kharchenko ◽  
Vladimir Novikov ◽  
Elena Komarovska-Porohnyavets ◽  
...  
Keyword(s):  
Biological Activity ◽  
Carboxylic Acids ◽  
Ethyl Esters

ChemInform Abstract: Synthesis and Biological Activity of Novel Ethyl Esters of 4-R-6,8-Dimethyl-1-oxo-1,2-dyhidropyrrolo[1,2-d] [1,2,4]triazine-7-carboxylic Acids.

ChemInform ◽  
2016 ◽  
Vol 47 (31) ◽  
Author(s):  
Valeriia Astakhina ◽  
Maxim Voievudskyi ◽  
Olexander Kharchenko ◽  
Vladimir Novikov ◽  
Elena Komarovska-Porohnyavets ◽  
...  
Keyword(s):  
Biological Activity ◽  
Carboxylic Acids ◽  
Ethyl Esters

Biological Activity of Novel N-Substituted Amides of endo-3- (3-Methylthio-1,2,4-triazol-5-yl)bicyclo[2.2.1]hept-5-ene-2- carboxylic Acid and N-Substituted Amides of 1-(5-Methylthio- 1,2,4-triazol-3-yl)cyclohexane-2-carboxylic Acids

2012 ◽  
Vol 67 (3-4) ◽  
pp. 123-128
Author(s):  
Anna Pachuta-Stec ◽  
Urszula Kosikowska ◽  
Anna Chodkowska ◽  
Monika Pitucha ◽  
Anna Malm ◽  
...  
Keyword(s):  
Biological Activity ◽  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Condensation Reaction ◽  
Primary Amines ◽  
Pharmacological Activities

N-Substituted amides of endo-3-(3-methylthio-1,2,4-triazol-5-yl)bicyclo[2.2.1]hept-5-ene- 2-carboxylic acid and 1-(5-methylthio-1,2,4-triazol-3-yl)cyclohexane-2-carboxylic acid were prepared by the condensation reaction of endo-S-methyl-N1-(bicyclo[2.2.1]hept-5-ene-2,3- dicarbonyl)isothiosemicarbazide and S-methyl-N1-(cyclohexane-2,3-dicarbonyl)isothiosemicarbazide with primary amines. The synthesized compounds were screened for their microbiological and pharmacological activities

The Hantzsch pyrrole synthesis

1970 ◽  
Vol 48 (11) ◽  
pp. 1689-1697 ◽  
Author(s):  
M. W. Roomi ◽  
S. F. MacDonald
Keyword(s):  
Carboxylic Acids ◽  
Ethyl Acetoacetate ◽  
Alkyl Group ◽  
Ethyl Esters ◽  
Hantzsch Synthesis ◽  
Butyl Esters ◽  
Alkyl Groups

Ethyl esters of 2-alkyl- and 2,4-dialkylpyrrole-3-carboxylic acids are obtained generally by extensions of the Hantzsch synthesis, benzyl and t-butyl esters when the 2-alkyl group is methyl. Hemopyrrole is obtained from butanal and ethyl acetoacetate in three steps. Pyrroles bearing higher alkyl groups or carbobenzoxy groups are reductively alkylated like the corresponding methylpyrroles and carbethoxy derivatives; t-butyl esters do not survive.

ChemInform Abstract: Synthesis and Biological Activity of 5-Alkyl-1,7,8-trisubstituted-6- fluoroquinoline-3-carboxylic Acids.

ChemInform ◽  
2010 ◽  
Vol 22 (27) ◽  
pp. no-no
Author(s):  
S. E. HAGEN ◽  
J. M. DOMAGALA ◽  
C. L. HEIFETZ ◽  
J. JOHNSON
Keyword(s):  
Biological Activity ◽  
Carboxylic Acids

Synthesis and Biological Activity of Arylcyclopentane-1-carboxylic Acids Aminoesters

2019 ◽  
Vol 89 (5) ◽  
pp. 1051-1054
Author(s):  
A. A. Aghekyan ◽  
G. G. Mkryan ◽  
A. S. Tsatinyan ◽  
G. V. Gasparyan
Keyword(s):  
Biological Activity ◽  
Carboxylic Acids

ChemInform Abstract: Synthesis and in vitro Biological Activity of Some 7-(5-Aminomethyl-2- isoxazolidinyl)quinolone-3-carboxylic Acids.

ChemInform ◽  
2010 ◽  
Vol 22 (19) ◽  
pp. no-no
Author(s):  
C. B. JUN. ZIEGLER ◽  
N. A. KUCK ◽  
T. W. STROHMEYER ◽  
Y. -I LIN
Keyword(s):  
Biological Activity ◽  
Carboxylic Acids
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