Adhesions as a risk factor for postoperative morbidity in patients undergoing repeat hepatectomy and the potential efficacy of adhesion barriers

2021 ◽  
Author(s):  
Satoshi Okubo ◽  
Junichi Shindoh ◽  
Yuta Kobayashi ◽  
Masaru Matsumura ◽  
Masaji Hashimoto
Keyword(s):  
Risk Factor ◽  
Postoperative Morbidity ◽  
Repeat Hepatectomy ◽  
Potential Efficacy

scholarly journals Sarcopenic obesity is a significant risk factor for postoperative morbidity after pancreatic surgery

HPB ◽  
2020 ◽  
Vol 22 ◽  
pp. S221-S222
Author(s):  
C. Ratnayake ◽  
M. Olsson ◽  
C. Wells ◽  
J. Windsor ◽  
S. Pandanaboyana
Keyword(s):  
Risk Factor ◽  
Pancreatic Surgery ◽  
Postoperative Morbidity ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Sarcopenic Obesity

scholarly journals Age Over 80 is a Possible Risk Factor for Postoperative Morbidity After a Laparoscopic Resection of Colorectal Cancer

2015 ◽  
Vol 31 (6) ◽  
pp. 228 ◽  
Author(s):  
Taekhyun Kang ◽  
Hyung Ook Kim ◽  
Hungdai Kim ◽  
Ho-Kyung Chun ◽  
Won Kon Han ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factor ◽  
Postoperative Morbidity ◽  
Laparoscopic Resection

scholarly journals HYPOALBUMINEMIA AS AN INDEPENDENT PROGNOSTIC RISK FACTOR FOR ADVERSE POST OPERATIVE OUTCOMES IN AN EMERGENCY LAPAROTOMY IN ADULT PATIENTS

2020 ◽  
pp. 1-3
Author(s):  
Sahista Hetamkhan Belim ◽  
Vidhyasagar M. Sharma
Keyword(s):  
Risk Factor ◽  
Postoperative Morbidity ◽  
Surgical Stress ◽  
Wound Dehiscence ◽  
Adverse Outcomes ◽  
Morbidity And Mortality ◽  
Control Group ◽  
Emergency Laparotomy ◽  
Strong Positive Correlation ◽  
Operative Outcomes

Background:Laparotomies are commonly performed surgeries in an emergency setting.The complications associated with these are a result of the activation of the surgical stress response,the magnitude and duration of which are proportional to the surgical injury.Albumin is an important negative phase reactant. The prevalence of hypoalbuminemia in surgical patients is quite common. Preoperative hypoalbuminemia is an independent risk factor for several adverse outcomes postoperatively, and it is one of the marker for nutritional status of the patient. Low level of albumin is a risk factor for postoperative morbidity and mortality of the patients. Objective: To study level of serum albumin and its correlation with postoperative morbidity and mortality. Materials and methods: 84 patients in the age group 18-75 years who underwent Emergency laparotomy were studied from March 2018 to April 2020 at GCS Medical College. Effect of hypoalbuminemia was estimated. Study group consisted of albumin level less than 3g/dl and control group of albumin more than 3g/dl. Both groups were studied for post-laparotomy complications and data was analysed. Results: Prevalence of hypoalbuminemia is common in patients undergoing emergency laparotomy. Hypoalbuminemia has strong positive correlation to post-operative adverse outcomes like seroma, wound dehiscence, wound infection, incisional hernia and mortality. Conclusion: Hypoalbuminemia is a significant and effective prognostic risk factor which predicts adverse post-operative outcomes in patients undergoing laparotomy.

scholarly journals Chemotherapy and Hepatic Steatosis: Impact on Postoperative Morbidity and Survival after Liver Resection for Colorectal Liver Metastases

2020 ◽  
pp. 1-8
Author(s):  
Jan C. Mahlmann ◽  
Thomas C. Wirth ◽  
Björn Hartleben ◽  
Harald Schrem ◽  
Jens F. Mahlmann ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Risk Factor ◽  
Liver Resection ◽  
Liver Metastases ◽  
Hepatic Steatosis ◽  
Colorectal Liver Metastases ◽  
Postoperative Morbidity ◽  
Cox Regression ◽  
Significant Risk ◽  
Cox Regression Analysis

<b><i>Background:</i></b> Hepatic steatosis and chemotherapy in the treatment of colorectal liver metastases (CLM) are often linked to increased mortality and morbidity after liver resection. This study evaluates the influence of macrovesicular hepatic steatosis and chemotherapeutic regimes on graded morbidity and mortality after liver resection for CLM. <b><i>Methods:</i></b> A total of 323 cases of liver resection for CLM were retrospectively analysed using univariable and multivariable linear, ordinal and Cox regression analyses. The resected liver tissue was re-evaluated by a single observer to determine the grade and type of hepatic steatosis. <b><i>Results:</i></b> Macrovesicular steatosis did not influence postoperative morbidity and survival, as evidenced by risk-adjusted multivariable Cox regression analysis (<i>p</i> = 0.521). Conversion chemotherapy containing oxaliplatin was an independent and significant risk factor for mortality in risk-adjusted multivariable Cox regression analysis (<i>p</i> = 0.005). Identified independently, significant risk factors for postoperative morbidity were neoadjuvant treatment of metastases of the primary tumour with irinotecan (<i>p</i> = 0.003), the duration of surgery in minutes (<i>p</i> = 0.001) and the number of intraoperatively transfused packed red blood cells (<i>p</i> ≤ 0.001). Surprisingly, macrovesicular hepatic steatosis was not a risk factor for postoperative morbidity and was even associated with lower rates of complications (<i>p</i> = 0.006). <b><i>Conclusion:</i></b> The results emphasize the multifactorial influence of preoperative liver damage and chemotherapy on the severity of postoperative morbidity, as well as the significant impact of conversion chemotherapy containing oxaliplatin on survival.

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