Severity and prognostic assessment of the endotoxin activity assay in biliary tract infection

2013 ◽  
Vol 21 (2) ◽  
pp. 120-127 ◽  
Author(s):  
Mari Sato ◽  
Ryusei Matsuyama ◽  
Toshiaki Kadokura ◽  
Ryutaro Mori ◽  
Takafumi Kumamoto ◽  
...  
Keyword(s):  
Tract Infection ◽  
Biliary Tract ◽  
Activity Assay ◽  
Biliary Tract Infection ◽  
Endotoxin Activity Assay ◽  
Prognostic Assessment ◽  
Endotoxin Activity

scholarly journals Intestinal fatty acid‐binding protein is a biomarker for diagnosis of biliary tract infection

JGH Open ◽  
2021 ◽  
Author(s):  
Yu‐Chieh Weng ◽  
Wei‐Ting Chen ◽  
Jung‐Chieh Lee ◽  
Yung‐Ning Huang ◽  
Chih‐Kai Yang ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Tract Infection ◽  
Biliary Tract ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Biliary Tract Infection ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals The prevalence of the iutA and ibeA genes in Escherichia coli isolates from severe and non-severe patients with bacteremic acute biliary tract infection is significantly different

Gut Pathogens ◽  
2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Mahoko Ikeda ◽  
Tatsuya Kobayashi ◽  
Fumie Fujimoto ◽  
Yuta Okada ◽  
Yoshimi Higurashi ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Tract Infection ◽  
Biliary Tract ◽  
Iron Acquisition ◽  
Tertiary Care ◽  
Care Hospital ◽  
Biliary Tract Infection ◽  
E Coli ◽  
Severe Group ◽  
Tract Infections

Abstract Background Although Escherichia coli is the most frequently isolated microorganism in acute biliary tract infections with bacteremia, data regarding its virulence are limited. Results Information on cases of bacteremia in acute biliary tract infection in a retrospective study was collected from 2013 to 2015 at a tertiary care hospital in Japan. Factors related to the severity of infection were investigated, including patient background, phylogenetic typing, and virulence factors of E. coli, such as adhesion, invasion, toxins, and iron acquisition. In total, 72 E. coli strains were identified in 71 cases, most of which primarily belonged to the B2 phylogroup (68.1%). The presence of the iutA gene (77.3% in the non-severe group, 46.4% in the severe group, P = 0.011) and the ibeA gene (9.1% in the non-severe group, and 35.7% in the severe group, P = 0.012) was significantly associated with the severity of infection. Among the patient characteristics, diabetes mellitus with organ involvement and alkaline phosphatase were different in the severe and non-severe groups. Conclusions We showed that bacteremic E. coli strains from acute biliary tract infections belonged to the virulent (B2) phylogroup. The prevalence of the iutA and ibeA genes between the two groups of bacteremia severity was significantly different.

Biliary tract infection caused by Listeria monocytogenes

2007 ◽  
Vol 29 (1) ◽  
pp. 6-8 ◽  
Author(s):  
C.V. Loupa ◽  
G. Kouppar ◽  
N. Kosionis ◽  
M. Zouberi Koliomichali ◽  
M.I. Lelekis
Keyword(s):  
Listeria Monocytogenes ◽  
Tract Infection ◽  
Biliary Tract ◽  
Biliary Tract Infection

scholarly journals Pathophysiologic Characterization of a Novel Rabbit Model of Biliary Tract Infection-Derived Sepsis

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Liangshuo Hu ◽  
Yichao Chai ◽  
Rui Xi ◽  
Haoyang Zhu ◽  
Yue Wang ◽  
...  
Keyword(s):  
Tract Infection ◽  
Biliary Tract ◽  
Rabbit Model ◽  
Biliary Tract Infection

scholarly journals 135. Clinical and Microbiologic Analysis of Risk Factors for Mortality in Patients with Carbapenem-Resistant Acinetobacter baumannii Bacteremia

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S95-S96
Author(s):  
Eunbeen Cho ◽  
Hyo-Ju Son ◽  
Seongman Bae ◽  
Hyeonji Seo ◽  
Eunmi Yang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Tract Infection ◽  
Combination Therapy ◽  
Acinetobacter Baumannii ◽  
Biliary Tract ◽  
Microbiological Analysis ◽  
Biliary Tract Infection ◽  
Clinical Issue ◽  
Catheter Related Infection ◽  
Carbapenem Resistant

Abstract Background Carbapenem-resistant Acinetobacter baumannii (CRAB) infection is an emerging clinical issue and shows high mortality rates. There are a few studies that have evaluated the microbiologic risk factors for mortality in CRAB bacteremia. Aim of this study is to identify the clinical and microbiologic risk factors for mortality in CRAB bacteremia. Methods Adult patients with monomicrobial CRAB bacteremia at a 2,700-bed tertiary hospital between December 2012 and December 2018 were retrospectively enrolled in the study. Risk factors for 30-day mortality were evaluated through a detailed clinical and microbiological analysis of study patients. All isolates collected on the first day of bacteremia were subjected to colistin susceptibility testing by broth microdilution and genotyping by multilocus sequence typing (MLST). Results A total of 164 patients were enrolled and 90 (55%) died within 30 days. Of the 164 patients, 111 (68%) were male and median age was 66.5 years. The most common MLST genotype was ST191 (80 isolates, 49%), followed by ST451 (14%) and ST784 (13%), and 12 (7%) isolates were resistant to colistin (MIC ≥4 mg/L). Deceased patients were more likely to have hematologic malignancy, neutropenia, pneumonia, and primary bacteremia; less likely to have solid tumor, catheter-related infection, and biliary tract infection; more likely to have a high Pitt bacteremia score; and less likely to receive appropriate antibiotic treatment, colistin, and combination therapy with colistin and tigecycline, compared with surviving patients (Table 1). Genotype, colistin MIC, and colistin resistance were not associated with mortality (Figure 1 and 2). In multivariable analysis, neutropenia (aOR, 3.25; 95% CI, 1.18–8.95), catheter-related infection (aOR, 0.33; 95% CI, 0.11–0.99), biliary tract infection (aOR, 0.20; 95% CI, 0.04–0.99), a high Pitt bacteremia score (aOR,1.42; 95% CI, 1.20–1.67), and combination therapy with colistin and tigecycline (aOR, 0.36; 95% CI, 0.14–0.92) were independent risk factors for mortality (Table 2). Conclusion Clinical factors such as the site of infection, severity of bacteremia, and specific combination therapy rather than microbiologic factors contributed to mortality in CRAB bacteremia. Appropriate combination therapy may help improving outcomes in CRAB bacteremia. Disclosures All authors: No reported disclosures.

Hemobilia with acute pancreatitis secondary to biliary tract infection

2019 ◽  
Vol 18 (6) ◽  
pp. 593-595
Author(s):  
Dong-Bao Li ◽  
Zu-Xiong Tang ◽  
Jian-Xin Ye ◽  
Zhi Li ◽  
Xiao-Hua Yang ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Tract Infection ◽  
Biliary Tract ◽  
Biliary Tract Infection

scholarly journals First report of biliary tract infection caused by multidrug-resistant Serratia fonticola

2020 ◽  
Vol 36 ◽  
pp. 100692
Author(s):  
P.D. Hai ◽  
L.T.V. Hoa ◽  
N.H. Tot ◽  
L.L. Phuong ◽  
V.V. Quang ◽  
...  
Keyword(s):  
Tract Infection ◽  
Biliary Tract ◽  
Multidrug Resistant ◽  
Biliary Tract Infection ◽  
First Report
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