E‐cadherin ( CDH1 ) gene ‐160C/A polymorphism and the risk of colorectal cancer: a meta‐analysis involving 17,291 subjects

2021 ◽  
Author(s):  
Chuncui Ye ◽  
Jun Wang
Keyword(s):  
Colorectal Cancer ◽  
Meta Analysis ◽  
Cdh1 Gene ◽  
E Cadherin

E-cadherin (CDH1) gene promoter polymorphism and the risk of colorectal cancer

2011 ◽  
Vol 27 (2) ◽  
pp. 151-158 ◽  
Author(s):  
Yadong Wang ◽  
Haiyan Yang ◽  
Li Li ◽  
Haiyu Wang ◽  
Congke Zhang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Gene Promoter ◽  
Promoter Polymorphism ◽  
Cdh1 Gene ◽  
Gene Promoter Polymorphism ◽  
E Cadherin

The E-Cadherin (CDH1) −C160A Polymorphism and Colorectal Cancer Susceptibility: A Meta-Analysis

2012 ◽  
Vol 31 (6) ◽  
pp. 1070-1077 ◽  
Author(s):  
Peiliang Geng ◽  
Yuying Chen ◽  
Juanjuan Ou ◽  
Xiaoling Yin ◽  
Rina Sa ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Susceptibility ◽  
Meta Analysis ◽  
E Cadherin

scholarly journals The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis

2008 ◽  
Vol 122 (11) ◽  
pp. 2573-2580 ◽  
Author(s):  
Xiang-Lin Tan ◽  
Alexandra Nieters ◽  
Silke Kropp ◽  
Michael Hoffmeister ◽  
Hermann Brenner ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cyclin D1 ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Control Study ◽  
E Cadherin

scholarly journals Effect of E-Cadherin (CDH1) -160C/A polymorphism on prostate cancer risk: a meta-analysis

2015 ◽  
Author(s):  
Bo Yang ◽  
Yi He ◽  
Xiaofei Wen ◽  
Hui Liu ◽  
Guoqiang Liao ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Transcriptional Activity ◽  
Meta Analysis ◽  
Prostate Cancer Risk ◽  
Positive Association ◽  
Population Based ◽  
Cdh1 Gene ◽  
Increased Risk ◽  
E Cadherin

E-Cadherin (CDH1) genetic variations may be involved in invasion and metastasis of various cancers by altering gene transcriptional activity of epithelial cells. However, published studies on the association of CDH1 gene polymorphisms and prostate cancer (PCA)risk remain contradictory, owing to differences in living habits and genetic backgrounds.To derive a more better and comprehensive conclusion, the present meta-analysis was performed.Electronic searches of several databases were conducted for all publications on the association between the CDH1 −160 C/A polymorphism and prostate cancer before Oct 2014. The odds ratio (OR) and its 95% confidence interval (CI) were used for statistical analysis.A total of 7 eligible studies including 1294 cases and 1782 controls were involved in this meta-analysis.Overall, meta-analysis indicated that the -160A allele carriers (AA, CA, AA+CA and A allele) had an increased risk of PCA compared with the homozygotes (CC). In the subgroup analyses by ethnicity, a positive association was found in Asians with A allele, AA, CA, AA+CA genotype and Caucasian descendants with AA genotype, dominant and recessive models. On the contrary, a decreased prostate cancer risk was found in Africans with heterozygous,dominant and allele models.Taken together,this meta-analysis showed that the CDH1 -160A allele might be a risk factor for prostate cancer in Asians and Caucasians. However, this result should be verified by additional population-based studies with large sample sizes.

614: Polymorphisms in the E-Cadherin (CDH1) Gene Promoter and the Risk of Bladder Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 198-198
Author(s):  
Lambertus A. Kiemeney ◽  
Kjeld P. Van Houwelingen ◽  
Manon Bogaerts ◽  
J. Alfred Witjes ◽  
Dorine W. Swinkels ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Gene Promoter ◽  
Cdh1 Gene ◽  
E Cadherin

Loss of E-cadherin expression in colorectal cancer

Endoscopy ◽  
2006 ◽  
Vol 37 (12) ◽  
Author(s):  
E Fox ◽  
DT Leahy ◽  
R Geraghty ◽  
D Keegan ◽  
A White ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
E Cadherin
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