Association of single‐nucleotide polymorphisms in TLR4 gene and gene–environment interaction with primary open angle glaucoma in a Chinese northern population

2019 ◽  
Vol 22 (1) ◽  
Author(s):  
Huijuan Liu ◽  
Shixin Qi ◽  
Wei He ◽  
Cuirong Chang ◽  
Yanhui Chen ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Environment Interaction ◽  
Nucleotide Polymorphisms ◽  
Open Angle ◽  
Northern Population ◽  
Single Nucleotide ◽  
Gene Environment Interaction ◽  
Gene Environment ◽  
Tlr4 Gene

Association of single-nucleotide polymorphisms in non-coding regions of the TLR4 gene with primary open angle glaucoma in a Mexican population

2016 ◽  
Vol 38 (4) ◽  
pp. 325-329 ◽  
Author(s):  
Jose Navarro-Partida ◽  
Beatriz Alvarado Castillo ◽  
Abril Bernardette Martinez-Rizo ◽  
Ramses Rosales-Diaz ◽  
Jesus Bernardino Velazquez-Fernandez ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Mexican Population ◽  
Nucleotide Polymorphisms ◽  
Open Angle ◽  
Single Nucleotide ◽  
Coding Regions ◽  
Tlr4 Gene

An update: mechanisms of microRNA in primary open-angle glaucoma

2020 ◽  
Author(s):  
Yuanping Wang ◽  
Lingzhi Niu ◽  
Jing Zhao ◽  
Mingxuan Wang ◽  
Ke Li ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Nucleotide Polymorphisms ◽  
Open Angle ◽  
Single Nucleotide ◽  
Optic Nerve Damage ◽  
The World ◽  
And Function ◽  
Main Factor

Abstract Glaucoma is a disease with characteristic optic neuropathy and loss of vision, leading to blindness, and primary open-angle glaucoma (POAG) is the most common glaucoma type throughout the world. Genetic susceptibility is the main factor in POAG, and most susceptibility genes cause changes in microRNA expression and function, thereby leading to POAG occurrence and development. Increasing evidence indicates that many microRNAs are involved in the regulation of intraocular pressure (IOP) and play an important role in the increase in IOP in POAG. Additionally, microRNA is closely related to optic nerve damage factors (mechanical stress, hypoxia and inflammation). This review discusses the effect of single-nucleotide polymorphisms in POAG-related genes on microRNA and the value of microRNA in the diagnosis and treatment of POAG.

5,10-Methylenetetrahydrofolate reductase single nucleotide polymorphisms and gene-environment interaction analysis in non-syndromic cleft lip/palate

2014 ◽  
Vol 122 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Bernardette Estandia-Ortega ◽  
José A. Velázquez-Aragón ◽  
Miguel A. Alcántara-Ortigoza ◽  
Miriam E. Reyna-Fabian ◽  
Sandra Villagómez-Martínez ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Cleft Lip ◽  
Methylenetetrahydrofolate Reductase ◽  
Interaction Analysis ◽  
Environment Interaction ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Gene Environment Interaction ◽  
Gene Environment ◽  
Cleft Lip Palate

Association of Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile with the risk of primary open angle glaucoma

2017 ◽  
Vol 255 (5) ◽  
pp. 995-1001 ◽  
Author(s):  
Jose Navarro-Partida ◽  
Abril Bernardette Martinez-Rizo ◽  
Pedro Ramirez-Barrera ◽  
Jesus Bernardino Velazquez-Fernandez ◽  
Veronica A Mondragon-Jaimes ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Nucleotide Polymorphisms ◽  
Open Angle ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Single Nucleotide

Evaluation of the IL1 Gene Cluster Single Nucleotide Polymorphisms in Primary Open-Angle Glaucoma Pathogenesis

2016 ◽  
Vol 20 (10) ◽  
pp. 633-636 ◽  
Author(s):  
Suddhasil Mookherjee ◽  
Deblina Banerjee ◽  
Subhadip Chakraborty ◽  
Indranil Mukhopadhyay ◽  
Abhijit Sen ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Gene Cluster ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Nucleotide Polymorphisms ◽  
Open Angle ◽  
Single Nucleotide
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