Sustained delivery of therapeutic concentrations of human clotting factor IX - a comparison of adenoviral and AAV vectors administeredin utero

2002 ◽  
Vol 4 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Holm Schneider ◽  
Christiane Mühle ◽  
Anne Marie Douar ◽  
Simon Waddington ◽  
Qiu-Jie Jiang ◽  
...  
Keyword(s):  
Factor Ix ◽  
Clotting Factor ◽  
Sustained Delivery ◽  
Human Clotting Factor

Efficient transfer and expression of human clotting factor IX cDNA in neonatal hemophilia B mice mediated by VSV-G pseudotyped retrovirus

2001 ◽  
Vol 46 (18) ◽  
pp. 1534-1538
Author(s):  
Hongwei Wang ◽  
Chenbo Ye ◽  
Li Chen ◽  
Xuefeng Wang ◽  
Xinfang Qiu ◽  
...  
Keyword(s):  
Factor Ix ◽  
Hemophilia B ◽  
Clotting Factor ◽  
B Mice ◽  
Human Clotting Factor ◽  
Efficient Transfer

Long-Term Expression of Human Clotting Factor IX from Retrovirally Transduced Primary Human KeratinocytesIn Vivo

1998 ◽  
Vol 9 (8) ◽  
pp. 1187-1195 ◽  
Author(s):  
Steve J. White ◽  
Sean M. Page ◽  
Paris Margaritis ◽  
George G. Brownlee
Keyword(s):  
Factor Ix ◽  
Clotting Factor ◽  
Human Clotting Factor

Expression of active human clotting factor IX from recombinant DNA clones in mammalian cells

Nature ◽  
1985 ◽  
Vol 315 (6021) ◽  
pp. 683-685 ◽  
Author(s):  
D. S. Anson ◽  
D. E. G. Austen ◽  
G. G. Brownlee
Keyword(s):  
Mammalian Cells ◽  
Recombinant Dna ◽  
Factor Ix ◽  
Clotting Factor ◽  
Human Clotting Factor

Production of human clotting Factor IX without toxicity in mice after vascular delivery of a lentiviral vector

2002 ◽  
Vol 20 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Lisa V. Tsui ◽  
Michael Kelly ◽  
Nathalie Zayek ◽  
Virginia Rojas ◽  
Ken Ho ◽  
...  
Keyword(s):  
Lentiviral Vector ◽  
Factor Ix ◽  
Clotting Factor ◽  
Human Clotting Factor

Safe and efficacious delivery of the human clotting factor IX gene to non human primates using a recombinant AAV vector produced in a fully-scalable GMP-compliant production system

2013 ◽  
Vol 221 ◽  
pp. S60
Author(s):  
Bart A. Nijmeijer ◽  
Harald Petry ◽  
Marc A. Sonnemans ◽  
Stuart G. Beattie ◽  
Lisa Spronck Florence Salmon ◽  
...  
Keyword(s):  
Production System ◽  
Factor Ix ◽  
Clotting Factor ◽  
Aav Vector ◽  
Human Clotting Factor
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