Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy

Xinhua Xie; Jiaoli Guo; Yanan Kong; Gene Xianquan Xie; Laishen Li; Ning Lv; Xiangsheng Xiao; Jun Tang; Xi Wang; Peng Liu; Mingtian Yang; Zeming Xie; Weidong Wei; Xiaoming Xie

doi:10.1002/jgm.1620

Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy

The Journal of Gene Medicine ◽

10.1002/jgm.1620 ◽

2011 ◽

Vol 13 (12) ◽

pp. 680-691 ◽

Cited By ~ 13

Author(s):

Xinhua Xie ◽

Jiaoli Guo ◽

Yanan Kong ◽

Gene Xianquan Xie ◽

Laishen Li ◽

...

Keyword(s):

Prostate Cancer ◽

Escherichia Coli ◽

Cancer Therapy ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Nucleoside Phosphorylase ◽

Prostate Cancer Therapy ◽

Targeted Expression

Download Full-text

Erratum: Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy

The Journal of Gene Medicine ◽

10.1002/jgm.2617 ◽

2012 ◽

Vol 14 (3) ◽

pp. 217-217

Author(s):

Xinhua Xie ◽

Jiaoli Guo ◽

Yanan Kong ◽

Gene Xianquan Xie ◽

Laishen Li ◽

...

Keyword(s):

Prostate Cancer ◽

Escherichia Coli ◽

Cancer Therapy ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Nucleoside Phosphorylase ◽

Prostate Cancer Therapy ◽

Targeted Expression

Download Full-text

1199. Novel Gene Therapy for Prostate Cancer: In Vivo-Targeted Expression of the E. Coli Purine Nucleoside Phosphorylase Gene by Adenoviral Delivery

Molecular Therapy ◽

10.1016/s1525-0016(16)44029-3 ◽

2002 ◽

Vol 5 (5) ◽

pp. S389-S390

Keyword(s):

Prostate Cancer ◽

Gene Therapy ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Nucleoside Phosphorylase ◽

E Coli ◽

Novel Gene ◽

Adenoviral Delivery ◽

Targeted Expression

Download Full-text

High-temperature cultivation and 5′ mRNA optimization are key factors for the efficient overexpression of thermostable Deinococcus geothermalis purine nucleoside phosphorylase in Escherichia coli

Journal of Biotechnology ◽

10.1016/j.jbiotec.2011.08.009 ◽

2011 ◽

Vol 156 (4) ◽

pp. 268-274 ◽

Cited By ~ 6

Author(s):

Kathleen Szeker ◽

Olli Niemitalo ◽

Marco G. Casteleijn ◽

André H. Juffer ◽

Peter Neubauer

Keyword(s):

Escherichia Coli ◽

High Temperature ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Key Factors ◽

Nucleoside Phosphorylase ◽

Deinococcus Geothermalis

Download Full-text

2-Chloro-2' -deoxyadenosine (Cladribine) and its Analogues are Good Substrates and Potent Selective Inhibitors of Escherichia coli Purine-Nucleoside Phosphorylase

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1995.886_3.x ◽

1995 ◽

Vol 233 (3) ◽

pp. 886-890 ◽

Cited By ~ 9

Author(s):

Agnieszka Bzowska ◽

Zygmunt Kazimierczuk

Keyword(s):

Escherichia Coli ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Selective Inhibitors ◽

Nucleoside Phosphorylase

Download Full-text

Synthesis of 3′-α-fluoronucleosides Using Pyrimidine Nucleoside Phosphorylase of Thermus thermophilus and Purine Nucleoside Phosphorylase of Escherichia coli

Life Chemistry Research ◽

10.1201/b18527-23 ◽

2015 ◽

pp. 191-200

Keyword(s):

Escherichia Coli ◽

Purine Nucleoside Phosphorylase ◽

Thermus Thermophilus ◽

Purine Nucleoside ◽

Pyrimidine Nucleoside ◽

Nucleoside Phosphorylase ◽

Pyrimidine Nucleoside Phosphorylase

Download Full-text

Antitumor effects of a dual-specific lentiviral vector carrying the Escherichia coli purine nucleoside phosphorylase gene

International Journal of Oncology ◽

10.3892/ijo.2017.3949 ◽

2017 ◽

Vol 50 (5) ◽

pp. 1612-1622

Author(s):

Xiaolong Wang ◽

Lei Sun ◽

Xuejun Sun ◽

Junhui Yu ◽

Kai Wang ◽

...

Keyword(s):

Escherichia Coli ◽

Purine Nucleoside Phosphorylase ◽

Lentiviral Vector ◽

Purine Nucleoside ◽

Antitumor Effects ◽

Nucleoside Phosphorylase

Download Full-text

Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene

Cancer Gene Therapy ◽

10.1038/cgt.2010.17 ◽

2010 ◽

Vol 17 (9) ◽

pp. 614-623 ◽

Cited By ~ 25

Author(s):

C-K Tai ◽

W Wang ◽

Y-H Lai ◽

C R Logg ◽

W B Parker ◽

...

Keyword(s):

Escherichia Coli ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Prodrug Activation ◽

Nucleoside Phosphorylase ◽

Activation Therapy ◽

Tumor Selective

Download Full-text

Purine-Nucleoside Phosphorylase from Salmonella typhimurium and Escherichia coli. Initial Velocity Kinetics, Ligand Binding, and Reaction Mechanism

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1976.tb10031.x ◽

1976 ◽

Vol 61 (2) ◽

pp. 377-386 ◽

Cited By ~ 28

Author(s):

Kaj Frank JENSEN

Keyword(s):

Escherichia Coli ◽

Reaction Mechanism ◽

Ligand Binding ◽

Salmonella Typhimurium ◽

Initial Velocity ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Nucleoside Phosphorylase

Download Full-text

Escherichia coli Purine Nucleoside Phosphorylase II, the Product of the xapA Gene

Journal of Molecular Biology ◽

10.1016/j.jmb.2005.02.019 ◽

2005 ◽

Vol 348 (1) ◽

pp. 113-125 ◽

Cited By ~ 13

Author(s):

Gert Dandanell ◽

Roman H. Szczepanowski ◽

Borys Kierdaszuk ◽

David Shugar ◽

Matthias Bochtler

Keyword(s):

Escherichia Coli ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Nucleoside Phosphorylase

Download Full-text

Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models

Gene Therapy ◽

10.1038/sj.gt.3301698 ◽

2002 ◽

Vol 9 (12) ◽

pp. 759-768 ◽

Cited By ~ 44

Author(s):

D Voeks ◽

R Martiniello-Wilks ◽

V Madden ◽

K Smith ◽

E Bennetts ◽

...

Keyword(s):

Prostate Cancer ◽

Gene Therapy ◽

Mouse Models ◽

Purine Nucleoside Phosphorylase ◽

Purine Nucleoside ◽

Nucleoside Phosphorylase

Download Full-text