scholarly journals Development of peripheral eosinophilia in inflammatory bowel disease patients on infliximab treated at a tertiary pediatric inflammatory bowel disease center is associated with clinically active disease but does not result in loss of efficacy or adverse outcomes

JGH Open ◽  
2020 ◽  
Vol 4 (4) ◽  
pp. 636-641
Author(s):  
Douglas Zabrowski ◽  
Danielle Abraham ◽  
Geoffrey Rosenthal ◽  
Howard Kader
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Adverse Outcomes ◽  
Peripheral Eosinophilia ◽  
Pediatric Inflammatory Bowel Disease ◽  
Inflammatory Bowel ◽  
Active Disease

scholarly journals Proper Use of Inflammatory Bowel Disease Drugs during Pregnancy

2016 ◽  
Vol 34 (Suppl. 1) ◽  
pp. 61-66 ◽  
Author(s):  
S.L. Kanis ◽  
C.J. van der Woude
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Bowel Disease ◽  
Adverse Outcome ◽  
Adverse Outcomes ◽  
Reproductive Age ◽  
Inflammatory Bowel ◽  
Preconceptional Counseling ◽  
Active Disease

Crohn's disease and ulcerative colitis, referred to as inflammatory bowel disease (IBD), are chronic, relapsing conditions. Patients are often diagnosed at a reproductive age, and therefore questions about fertility and reproductions often arise. Preconceptional counseling is the most important aspect in the management of IBD patients with a pregnancy wish. Patients should be counseled on the influence of IBD and IBD drugs on pregnancy. Most drugs are not related to adverse outcome while used during pregnancy. Active disease is related to adverse outcomes; therefore, it is of utmost importance to strive for remission before conception and during pregnancy.

P810 Geriatric impairments in older inflammatory bowel disease patients are associated with higher disease burden: results of a multicentre cohort study

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S632-S633
Author(s):  
V Asscher ◽  
S Waars ◽  
A van der Meulen-de Jong ◽  
R Stuyt ◽  
S Brouwer ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Disease Activity ◽  
Bowel Disease ◽  
Disease Burden ◽  
Handgrip Strength ◽  
Improve Patient Care ◽  
Adverse Outcomes ◽  
Functional Domain ◽  
Inflammatory Bowel ◽  
Active Disease

Abstract Background The population of older patients with Inflammatory Bowel Diseases (IBD) is expanding. Knowledge on the prevalence and impact of geriatric impairments is scarce in this heterogenous group. In other fields of medicine, it has been established that geriatric impairments associate with adverse outcomes. Therefore, the aims of our study were to assess the prevalence of geriatric impairments in older IBD patients and to evaluate the association between geriatric impairments and disease burden of IBD through the short Inflammatory Bowel Disease Questionnaire (sIBDQ). Methods Consecutive IBD patients aged ≥65 years were included at outpatient departments and infusion centres of four hospitals in The Netherlands. Comorbidity, polypharmacy and malnutrition (somatic domain), cognitive impairment and depressive symptoms (mental domain), handgrip strength and gait speed (physical domain) and impairments in (instrumental) activities of daily living ((I)ADL) (functional domain) were assessed. Disease activity was assessed through Harvey Bradshaw Index (HBI) or partial Mayo Score (pMS) (remission: HBI<5 or pMS<2); The sIBDQ was used to assess IBD disease burden. Association between geriatric impairments and sIBDQ was assessed using multiple linear regression, including confounders age, sex, IBD type, disease duration and disease activity. Results In total, 336 patients were included: median age 70.0 (IQR 67.0–73.0); 161 CD (47.9%); 71 active disease (21.1%); mean sIBDQ 59.7 (SD 8.1). Prevalence of geriatric impairments is tabulated (Table 1). Both active disease and the presence of two or more impaired domains were statistically significantly and independently associated with a higher disease burden (lower sIBDQ) (Table 2). Conclusion In an older IBD patient population, geriatric impairments are frequently encountered and associate with a higher disease burden. These results are a call for more research on the relationship between geriatric impairments and IBD disease burden to improve patient care in older IBD patients.

Pediatric Inflammatory Bowel Disease INTERMED

2019 ◽  
Author(s):  
Janice S. Cohen ◽  
John S. Lyons ◽  
Eric I. Benchimol ◽  
Nicholas Carman ◽  
Camille Guertin ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Pediatric Inflammatory Bowel Disease ◽  
Inflammatory Bowel
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