scholarly journals Surveillance for colorectal cancer and chemoprevention in ulcerative and Crohn's colitis: The need for clinical strategies to increase effectiveness

JGH Open ◽  
2019 ◽  
Vol 3 (5) ◽  
pp. 370-373
Author(s):  
Affifa Farrukh ◽  
John F Mayberry
2021 ◽  
Author(s):  
Grace Gatenby ◽  
Tamara Glyn ◽  
John Pearson ◽  
Richard Gearry ◽  
Timothy Eglinton

2012 ◽  
Vol 6 (8) ◽  
pp. 824-829 ◽  
Author(s):  
Robert J. Basseri ◽  
Benjamin Basseri ◽  
Maria E. Vassilaki ◽  
Gil Y. Melmed ◽  
Andrew Ippoliti ◽  
...  

2016 ◽  
Vol 31 (5) ◽  
pp. 973-982 ◽  
Author(s):  
Jochen K. Lennerz ◽  
Kimberley W. J. van der Sloot ◽  
Long Phi Le ◽  
Julie M. Batten ◽  
Jae Young Han ◽  
...  

2020 ◽  
Vol 36 (1) ◽  
pp. 141-150
Author(s):  
Leonie E. Vetter ◽  
Susanne Merkel ◽  
Alan Bénard ◽  
Christian Krautz ◽  
Maximilian Brunner ◽  
...  

Abstract Purpose Colorectal cancer is a well-recognized complication of inflammatory bowel diseases (IBD), such as ulcerative colitis (UC) and Crohn’s colitis (CC). In this study, we assess the clinico-pathological features and outcomes of patients with colorectal cancer from UC in comparison with CC. Methods Data of all patients with colitis-associated cancer (CAC) who underwent surgery at Erlangen or Würzburg University Clinic between 1995 and 2015 were selected. Clinical, histopathological, and survival data were analyzed retrospectively. Results Of all 88 patients with CAC, 20 patients had Crohn’s colitis and 68 patients had ulcerative colitis. We observed a young median age at tumor diagnosis (49.5 years UC; 45.5 years CC, p = 0.208) in both diseases and a long median disease duration before CAC (19 years UC; 18 years CC; p = 0.840). Patients with CC suffered more often from rectal cancer (14 (70.0%) in CC; 23 (33.8%) in UC; p = 0.005) and advanced tumor stages (8 (47.0%) pT4 in CC; 14 (25.0%) pT4/ypT4 in UC; p = 0.008). Five-year overall survival rate was 39.3% for CC and 67.1% for UC (p = 0.009 for difference between the groups). Survival did not differ significantly between UC and CC in the multivariate analysis after correction for UICC tumor stage. Conclusion CAC in CC showed advanced tumor stages associated with reduced survival compared with CAC in UC. This may be explained by less intense surveillance in patients with CC leading to delayed cancer diagnosis.


2013 ◽  
Vol 37 (4) ◽  
pp. 902-910 ◽  
Author(s):  
Stefano Scaringi ◽  
Carmela Di Martino ◽  
Daniela Zambonin ◽  
Marilena Fazi ◽  
Giuseppe Canonico ◽  
...  

2011 ◽  
Vol 140 (5) ◽  
pp. S-755
Author(s):  
Tibor Hlavaty ◽  
Martin Huorka ◽  
Tomas Koller ◽  
Peter Zita ◽  
Ema Kresanova ◽  
...  

2010 ◽  
Vol 138 (5) ◽  
pp. S-443 ◽  
Author(s):  
Robert J. Basseri ◽  
Benjamin Basseri ◽  
Andrew Ippoliti ◽  
Eric A. Vasiliauskas ◽  
Gil Y. Melmed ◽  
...  

1995 ◽  
Vol 108 (4) ◽  
pp. A822
Author(s):  
J. George ◽  
G.M. Groisma ◽  
N. Harpaz

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