Three‐dimensional echocardiographic comparison of left ventricular geometry and systolic function between dilated cardiomyopathy and mitral regurgitation with similar left ventricular dilation

2019 ◽  
Vol 48 (1) ◽  
pp. 29-37
Author(s):  
DeCai Zeng ◽  
Ji Wu ◽  
Shui‐Shun Wu ◽  
Hai‐Hong Lin ◽  
Hui Chen
Keyword(s):  
Mitral Regurgitation ◽  
Dilated Cardiomyopathy ◽  
Systolic Function ◽  
Three Dimensional ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Dilation ◽  
Ventricular Geometry ◽  
Left Ventricular Dilation

Relationships between left ventricular geometry and remodeling in dilated cardiomyopathy

2019 ◽  
Vol 67 (4) ◽  
Author(s):  
Ewa Dziewięcka ◽  
Sylwia Wiśniowska-Śmiałek ◽  
Lusine Khachatryan ◽  
Aleksandra Karabinowska ◽  
Maria Szymonowicz ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry

Procollagen type III amino-terminal propeptide: a serum biomarker of left ventricular remodelling in paediatric dilated cardiomyopathy

2013 ◽  
Vol 25 (2) ◽  
pp. 228-236 ◽  
Author(s):  
Beth D. Kaufman ◽  
Nancy Videon ◽  
Xuemei Zhang ◽  
Matthew A. Harris ◽  
Robert E. Shaddy ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Left Ventricular ◽  
Cardiac Remodelling ◽  
Idiopathic Dilated Cardiomyopathy ◽  
Ventricular Dilation ◽  
Type Iii ◽  
Procollagen Type ◽  
Amino Terminal ◽  
Left Ventricular Dilation ◽  
Prospective Longitudinal

AbstractBackgroundProcollagen type III amino-terminal propeptide is a collagen III cleavage product released in blood. The serum levels of this propeptide in adults with dilated cardiomyopathy are associated with cardiac remodelling and prognosis. The utility of procollagen type III amino-terminal propeptide as a biomarker in paediatric dilated cardiomyopathy is unknown.MethodsThis was a prospective, longitudinal study of children with dilated cardiomyopathy and changes in procollagen type III amino-terminal propeptide. The serum level of propeptide was measured serially, compared with paediatric normal values, and correlated with clinical status and left ventricular size and function on echocardiograms and cardiac magnetic resonance imaging.ResultsProcollagen type III amino-terminal propeptide was measured serially in 149 samples from 39 patients, age 9.0±6.4 years, followed up for 16.8±16.3 months. Procollagen type III amino-terminal propeptide in dilated cardiomyopathy was higher than in normal children. On multivariate analyses, procollagen type III amino-terminal propeptide had a positive correlation with left ventricular dilation, left ventricular end-diastolic diameter index (p<0.0001), and left ventricular end-diastolic diameter Z-score (p=0.0003), and a negative correlation with shortening fraction changes over time (p=0.001). Patients with myocarditis (n=12) had higher procollagen type III amino-terminal propeptide values than those with idiopathic dilated cardiomyopathy (n=20).ConclusionsProcollagen type III amino-terminal propeptide increases with left ventricular dilation and decreases with improvement in systolic function in paediatric dilated cardiomyopathy, indicating a role as a biomarker of cardiac remodelling in children. The diagnostic utility of procollagen type III amino-terminal propeptide to differentiate myocarditis from idiopathic dilated cardiomyopathy warrants further investigation.

Disparate Effects of Obesity and Left Ventricular Geometry on Mortality in 8088 Elderly Patients with Preserved Systolic Function

2009 ◽  
Vol 121 (3) ◽  
pp. 119-125 ◽  
Author(s):  
Carl J. Lavie ◽  
Richard V. Milani ◽  
Dharmendrakumar Patel ◽  
Surya M. Artham ◽  
Hector O. Ventura
Keyword(s):  
Elderly Patients ◽  
Systolic Function ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry
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