Associations between quantitative evaluation of bowel wall microvascular flow by contrast‐enhanced ultrasound and indices of disease activity in Crohn's disease patients using both bolus and infusion techniques

2019 ◽  
Vol 47 (8) ◽  
pp. 453-460
Author(s):  
Petros Zezos ◽  
Eran Zittan ◽  
Shadman Islam ◽  
John Hudson ◽  
Ofer Ben‐Bassat ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Quantitative Evaluation ◽  
Bowel Wall ◽  
Contrast Enhanced Ultrasound ◽  
Microvascular Flow ◽  
Contrast Enhanced

scholarly journals Dynamic contrast-enhanced ultrasound of the bowel wall with quantitative assessment of Crohn’s disease activity in childhood

2016 ◽  
Vol 50 (4) ◽  
pp. 347-354 ◽  
Author(s):  
Damjana Kljucevsek ◽  
Dubravka Vidmar ◽  
Darja Urlep ◽  
Rok Dezman
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Kinetic Parameters ◽  
Crohn Disease ◽  
Quantitative Assessment ◽  
Bowel Wall ◽  
Contrast Enhanced Ultrasound ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced

Abstract Background Contrast-enhanced ultrasound (CEUS) has become an established non-invasive, patient-friendly imaging technique which improves the characterization of lesions. In addition, dynamic contrast-enhanced ultrasound (DCE-US) provides valuable information concerning perfusion of examined organs. This review addresses current applications of CEUS in children, focused on DCE-US of the bowel wall in patients with Crohn disease, which enables realtime assessment of the bowel wall vascularity with semi-quantitative and quantitative assessment of disease activity and response to medical treatment. Conclusions Crohn’s disease is a chronic inflammatory relapsing disease. Frequent imaging re-evaluation is necessary. Therefore, imaging should be as little invasive as possible, children friendly with high diagnostic accuracy. US with wide varieties of techniques, including CEUS/DCE-US, can provide an important contribution for diagnosing and monitoring a disease activity. Even if the use of US contrast agent is off-label in children, it is welcome and widely accepted for intravesical use, and a little less for intravenous use, manly in evaluation of parenchymal lesions. To our knowledge this is the first time that the use of DCE-US in the evaluation of activity of small bowel Crohn disease with quantitative assessment of kinetic parameters is being described in children. Even if the results of the value and accuracy of different quantitative kinetic parameters in published studies in adult population often contradict one another there is a great potential of DCE-US to become a part of the entire sonographic evaluation not only in adults, but also in children. Further control studies should be performed.

scholarly journals P253 Conventional and contrast-enhanced ultrasound (CEUS) in the evaluation of Crohn's disease activity

2014 ◽  
Vol 8 ◽  
pp. S168-S169
Author(s):  
L. Ballesteros ◽  
M. Calvo ◽  
M.P. Delgado ◽  
A.M. Martín ◽  
P. Martínez ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Crohn’S Disease Activity

Dynamic Contrast-Enhanced MRI of the Bowel Wall for Assessment of Disease Activity in Crohn's Disease

2006 ◽  
Vol 186 (5) ◽  
pp. 1384-1392 ◽  
Author(s):  
Jasper Florie ◽  
Martin N. J. M. Wasser ◽  
Kasia Arts-Cieslik ◽  
Erik M. Akkerman ◽  
Peter D. Siersema ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Bowel Wall ◽  
Dynamic Contrast Enhanced Mri ◽  
Dynamic Contrast Enhanced ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Assessment Of Disease Activity ◽  
Contrast Enhanced Mri
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