Carotid artery diameter and wall stiffness in proteinuric renal disease without severely reduced kidney function

2015 ◽  
Vol 44 (3) ◽  
pp. 175-181 ◽  
Author(s):  
MariaRosaria Iannuzzi ◽  
Antonio D'Angelillo ◽  
Antonia Tortori ◽  
Dario Pazzano ◽  
Luca De Serio ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Renal Disease ◽  
Kidney Function ◽  
Wall Stiffness ◽  
Reduced Kidney Function ◽  
Proteinuric Renal Disease

Abstract P302: Longitudinal Evaluation of Impact and Results of the Mississippi Kidney Foundation’s Renal Evaluation and Assessment Program (REAP)

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Laura S Latham ◽  
Adam S Woodson ◽  
Deborah S Minor ◽  
Lynda M Richards ◽  
Gail G Sweat ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Renal Disease ◽  
Patient Care ◽  
Kidney Function ◽  
Rural Areas ◽  
Disease Risk ◽  
Elevated Blood ◽  
Reduced Kidney Function ◽  
The Impact

Introduction: Health fair-type screenings are one of the most recognizable forms of community-based health promotion. Though these screenings offer benefits in theory, little evidence supports their value. Through REAP, Mississippi Kidney Foundation routinely provides screenings for cardiovascular and renal disease risk factors. At each screening, participants obtain blood pressure, height, weight, laboratory assessments (metabolic/renal blood chemistries, complete blood count, total cholesterol, urinalysis) and complete a questionnaire regarding risk factors and disease history. Participants also receive written information about values/goals and consultation with a healthcare provider. Without a systematic evaluation, the overall value of this program is unknown. The purpose of this study was to review the impact and results of REAP and identify any changes that could improve outreach and patient care. Methods: We reviewed demographics and prevalence of cardiovascular and renal disease risk factors among participants over the previous 4 years (2010-2013). Screening sites were classified as urban or rural, according to census data. Risk factors were defined as elevated blood pressure (SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg), cholesterol (total > 200 mg/dL), or blood glucose (fasting ≥ 100 mg/dL); reduced kidney function (elevated BUN/Cr and/or eGFR < 60 ml/min); and proteinuria (≥ 30 mg/dL). Results: Over the review period, 57 screenings were performed at 34 sites, 15 classified as rural. Of the 5,545 participants, 4,299 were at urban and 1,246 at rural sites. Overall, 1,760 (32%) had elevated blood pressure (36% vs 31%, rural vs urban, respectively), 2,013 (36%, 40% vs 35%) elevated cholesterol and 1,046 (19%, 23% vs 18%) elevated glucose. Reduced kidney function was identified in 762 (14%, 15% vs 13%) participants, while 1,423 (26%, 29% vs 25%) had proteinuria. Among those reporting ethnicity (n=1,948) and gender (n=3,164), 614 (32%) were Caucasian, 1,290 (66%) African-American, and 2,270 (72%) female. Conclusions: Through this review, we determined that though REAP appears to target at risk populations, further efforts are needed to improve participation of males and those in rural areas. Elevated risk factors were more prevalent in rural areas; however, this may reflect differences in treatment rates, not absolute values. To better assess the impact of REAP, define risk factors, and influence patient care, we identified that more rigorous tracking, review of disease and treatment history, and further assessments are needed (i.e. full lipid panel). A graded system targeting patient follow-up is necessary, particularly among those at greatest risk. Based on these findings, these changes will be implemented, along with a post-screening evaluation of participants’ perceived benefits and result utilization.

scholarly journals Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function

JAMA ◽  
2019 ◽  
Vol 322 (12) ◽  
pp. 1167 ◽  
Author(s):  
Christianne L. Roumie ◽  
Jonathan Chipman ◽  
Jea Young Min ◽  
Amber J. Hackstadt ◽  
Adriana M. Hung ◽  
...  
Keyword(s):  
Kidney Function ◽  
Cardiovascular Events ◽  
Major Adverse Cardiovascular Events ◽  
Patients With Diabetes ◽  
Reduced Kidney Function

scholarly journals Reduced Kidney Function and Relative Hypocalciuria—Observational, Cross-Sectional, Population-Based Data

2020 ◽  
Vol 9 (12) ◽  
pp. 4133
Author(s):  
Massimo Cirillo ◽  
Giancarlo Bilancio ◽  
Pierpaolo Cavallo ◽  
Francesco Giordano ◽  
Gennaro Iesce ◽  
...  
Keyword(s):  
Kidney Function ◽  
Population Based ◽  
Calcium Handling ◽  
Urine Calcium ◽  
Cross Sectional ◽  
Dihydroxyvitamin D ◽  
1,25 Dihydroxyvitamin D ◽  
Calcium Load ◽  
Reduced Kidney Function ◽  
Low Serum

This observational, cross-sectional, epidemiological analysis investigated relationships of kidney function to urine calcium and other variables. The analyses targeted two population-based samples of adults (Gubbio study and Moli-sani study: n = 3508 and 955, respectively). Kidney function was assessed as estimated glomerular filtration rate (eGFR). Calcium/creatinine ratio (Ca/Cr) was used as index of urinary calcium in timed overnight urine under fed condition (Gubbio study), morning urine after overnight fast (Gubbio study), and first-void morning urine (Moli-sani study). Moli-sani study included also data for glomerular filtered calcium load, tubular calcium handling, and serum phosphorus, parathyroid hormone, 1,25-dihydroxyvitamin D, calcium, and 25-hydroxyvitamin D. eGFR positively and independently related to Ca/Cr (p < 0.001). In multivariate analyses, eGFR lower by 10 mL/min × 1.73 m2 related to overnight urine Ca/Cr lower by 14.0 mg/g in men and 17.8 mg/g in women, to morning urine Ca/Cr lower by 9.3 mg/g in men and 11.2 mg/g in women, and to first-void urine Ca/Cr lower by 7.7 mg/g in men and 9.6 mg/g in women (p < 0.001). eGFR independently related to glomerular filtered calcium load (p < 0.001) and did not relate to tubular calcium handling (p ≥ 0.35). In reduced eGFR only (<90 mL/min × 1.73 m2), low urine Ca/Cr independently related to low serum 1,25-dihydroxyvitamin D (p = 0.002) and did not relate to hyperphosphatemia, high serum parathyroid hormone, or hypocalcemia (p ≥ 0.14). Population-based data indicated consistent associations of lower kidney function with lower urine calcium due to reduction in glomerular filtered calcium. In reduced kidney function, relative hypocalciuria associated with higher prevalence of low serum 1,25-dihydroxyvitamin D.

scholarly journals Benefit of Ezetimibe Added to Simvastatin in Reduced Kidney Function

2017 ◽  
Vol 28 (10) ◽  
pp. 3034-3043 ◽  
Author(s):  
John W. Stanifer ◽  
David M. Charytan ◽  
Jennifer White ◽  
Yuliya Lokhnygina ◽  
Christopher P. Cannon ◽  
...  
Keyword(s):  
Kidney Function ◽  
Reduced Kidney Function

scholarly journals Albuminuria, Reduced Kidney Function, and the Risk of ST‐ and non–ST‐segment–elevation myocardial infarction

2018 ◽  
Vol 7 (20) ◽  
Author(s):  
Sonali N. de Chickera ◽  
Sarah E. Bota ◽  
John Paul Kuwornu ◽  
Harindra C. Wijeysundera ◽  
Amber O. Molnar ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Kidney Function ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Reduced Kidney Function

Increased plasma acylation-stimulating protein in pediatric proteinuric renal disease

2008 ◽  
Vol 23 (6) ◽  
pp. 959-964 ◽  
Author(s):  
Jin Hui Tang ◽  
Yu Wen ◽  
Fei Wu ◽  
Xiao Y. Zhao ◽  
Mei X. Zhang ◽  
...  
Keyword(s):  
Renal Disease ◽  
Acylation Stimulating Protein ◽  
Proteinuric Renal Disease
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