Drug biotransformation process favored by fungal biofilms formed on a proposed fixed bed‐airlift hybrid reactor

Author(s):  
Luiz F Bianchini ◽  
Romeu CP Silva Ramos ◽  
Nicoly S Oliveira ◽  
Rafaela C Paula ◽  
Rosimeire T Rosa ◽  
...  
Author(s):  
Shashi Kumar ◽  
Tanvi Gaba ◽  
Surendra Kumar

A mathematical model is presented to investigate the performance of tubular catalytic membrane reactor for dehydrogenation of cyclohexane using a FAU type zeolite membrane. The empirical correlations for the permeance of cyclohexane, benzene and hydrogen through FAU type zeolite membrane as a function of temperature have been developed. Three reactor configurations have been considered: conventional fixed bed, full length membrane reactor and hybrid reactor. The reactor performance has been studied in terms of conversion of cyclohexane to produce hydrogen. The observed conversions are ranked in the order: full length membrane reactor > hybrid reactor > fixed bed reactor. The simulation studies have been carried out for two feed conditions: one with hydrogen and another without hydrogen. The effect of cofeeding of hydrogen, sweep gas flow rate variation, and dilution ratio on the conversion of cyclohexane has been investigated in detail. The maximum percent increase in conversion of cyclohexane has been obtained at 473 K in hybrid as well as in membrane reactor. This temperature is also found to be optimum for sweep gas flow rate of 4.5 x 10-5 mol s-1. The conversion is observed to be suppressed by cofeeding of hydrogen and percent reduction is lowest at high temperature of 490 K in membrane reactor. The enhancement in the conversion is observed as a consequence of dilution of the feed with inert gas. The results reveal that hybrid reactor is not necessarily a better choice than the full length membrane reactor. However, at the expense of loss of reactant, hybrid reactor is better than full length membrane reactor.


The increase of demands on treatment efficiency and cost effective solution for municipal and Industrial wastewater treatment technologies leads to new interest in the biofilm technology. Different fixed growth biofilm reactors are commercially used to increase wastewater treatment efficacy, saving space and energy. Aerated Submerged Fixed Biofilm Bed (SFBB) reactors work based on biofilms attached to plastic supports. Mixing and transport processes within the fixed media are achieved by the aeration in aerobic systems (oxidation of organic compounds and nitrification), and denitrification can be realized in anoxic conditions. The concept of application the moving bed in this study for denitrification reactor (MBDR) has been considered as a viable extension of the capabilities of a SFBB plant in the anaerobic-denitrification stage. Therefore, this novel study was implemented as pilot hybrid-reactor-container-plant to treat municipal wastewater of 200 PE, based on a combination of an aerated submerged fixed bed biofilm (SFBB) and an anoxic moving bed denitrification (MBDR) reactor. The one-year evaluation of this concept shows high nitrification, denitrification rates and, BOD reduction; by controlling the effluent (BOD5≤10 mg/l, COD ≤100 mg/l, TSS: ≤25 mg/l, NH4-: ≤2 mgN/l, NO3≤10 mgN/l)). However, Implementing of certain novel elements leads to improve operation process: (Mixing, intermediate solids removal unit, applicability of Moving bed for denitrification and submerged fixed film in aerobic reactor..etc).


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