Fermentation optimization for the production of lovastatin byAspergillus terreus: use of response surface methodology

2004 ◽  
Vol 79 (10) ◽  
pp. 1119-1126 ◽  
Author(s):  
JL Casas López ◽  
JA Sánchez Pérez ◽  
JM Fernández Sevilla ◽  
FG Acién Fernández ◽  
E Molina Grima ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Fermentation Optimization

scholarly journals Screening and Application of Cyberlindnera Yeasts to Produce a Fruity, Non-Alcoholic Beer

Fermentation ◽  
2019 ◽  
Vol 5 (4) ◽  
pp. 103 ◽  
Author(s):  
Konstantin Bellut ◽  
Maximilian Michel ◽  
Martin Zarnkow ◽  
Mathias Hutzler ◽  
Fritz Jacob ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Ethanol Production ◽  
Response Surface ◽  
Sensory Evaluation ◽  
Pilot Scale ◽  
Fermentation Optimization ◽  
Production Methods ◽  
Pitching Rate ◽  
High Ester ◽  
Saccharomyces Yeasts

Non-alcoholic beer (NAB) is enjoying growing demand and popularity due to consumer lifestyle trends and improved production methods. In recent years in particular, research into the application of non-Saccharomyces yeasts to produce NAB via limited fermentation has gained momentum. Non-Saccharomyces yeasts are known to produce fruity aromas, owing to a high ester production. This trait could be harnessed to mask the often-criticized wort-like off-flavor of NAB produced via limited fermentation. Six Cyberlindnera strains were characterized and screened in wort extract. Four of the six strains produced a pleasant, fruity aroma while exhibiting low ethanol production. The strain Cyberlindnera subsufficiens C6.1 was chosen for fermentation optimization via response surface methodology (RSM) and a pilot-scale (60 L) brewing trial with subsequent sensory evaluation. A low fermentation temperature and low pitching rate enhanced the fruitiness and overall acceptance of the NAB. The NAB (0.36% ABV) produced on pilot-scale was significantly more fruity and exhibited a significantly reduced wort-like off-flavor compared to two commercial NABs. This study demonstrated the suitability of Cyberlindnera subsufficiens to produce a fruity NAB, which can compete with commercial NABs. The outcome strengthens the position of non-Saccharomyces yeasts as a serious and applicable alternative to established methods in NAB brewing.

scholarly journals Tối ưu sản xuất tạo sinh khối chủng Bacillus licheniformis B1 bằng phương pháp đáp ứng bề mặt

2019 ◽  
Vol 16 (6) ◽  
pp. 190
Author(s):  
Võ Hồng Phượng ◽  
Nguyễn Hoàng Tuấn ◽  
Phạm Thị Huyền Diệu ◽  
Nguyễn Thị Lan Chi ◽  
Lê Thị Bích Thủy ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Biomass Production ◽  
Bacillus Licheniformis ◽  
Submerged Fermentation ◽  
Culture Medium ◽  
Fermentation Optimization

The production of biomass from Bacillus licheniformsis B1 was investigated in submerged fermentation. Optimization of culture medium was carried out by using response surface methodology (RSM). The B1 biomass production was also significantly affected by dextrose, soya, CaCl2. In addition, while the optimum cultivation parameters were (g/L): 44.026 of dextrose, 34.025 of soya and 3.491 of CaCl2, the prediction of biomass production of B1 was 6.05 x 109 CFU ml-1.

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