scholarly journals Loss of melusin is a novel, neuronal NO synthase/FoxO3‐independent master switch of unloading‐induced muscle atrophy

2020 ◽  
Vol 11 (3) ◽  
pp. 802-819 ◽  
Author(s):  
Maurizio Vitadello ◽  
Matteo Sorge ◽  
Elena Percivalle ◽  
Elena Germinario ◽  
Daniela Danieli‐Betto ◽  
...  
Keyword(s):  
Muscle Atrophy ◽  
No Synthase ◽  
Neuronal No Synthase

Expression of neuronal no synthase in the human gastrointestinal tract

1995 ◽  
Vol 108 (4) ◽  
pp. A623
Author(s):  
M. John ◽  
B. Schätzmüller ◽  
A. Schmitt-Graeff ◽  
C. Ransco ◽  
H. Buhr ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
No Synthase ◽  
Human Gastrointestinal Tract ◽  
Neuronal No Synthase

Inducible NO synthase II and neuronal NO synthase I are constitutively expressed in different structures of guinea pig skeletal muscle: implications for contractile function

1996 ◽  
Vol 10 (14) ◽  
pp. 1614-1620 ◽  
Author(s):  
Ingolf Gath ◽  
Ellen I. Closs ◽  
Ute Gödtel‐Armbrust ◽  
Sandra Schmitt ◽  
Masaki Nakane ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Guinea Pig ◽  
Contractile Function ◽  
No Synthase ◽  
Neuronal No Synthase ◽  
Inducible No Synthase

P1-152 - High sucrose feeding-induced abnormalities of neuronal NO synthase in rat pancreatic bêta-cells and skeletal muscle

2006 ◽  
Vol 67 (5) ◽  
pp. 460-461
Author(s):  
K. Mezghenna ◽  
S. Péraldi-Roux ◽  
G. Dubois ◽  
M. Manteghetti ◽  
M. Tournier ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Beta Cells ◽  
Pancreatic Beta Cells ◽  
No Synthase ◽  
Neuronal No Synthase ◽  
Sucrose Feeding ◽  
High Sucrose Feeding ◽  
High Sucrose

scholarly journals Neuronal NO Synthase–Derived NO

2008 ◽  
Vol 102 (2) ◽  
pp. 148-150 ◽  
Author(s):  
Norio Fukuda ◽  
Jin O-Uchi ◽  
Satoshi Kurihara
Keyword(s):  
No Synthase ◽  
Neuronal No Synthase

scholarly journals Metabolism of Aminoguanidine, Diaminoguanidine, andNG-Amino-l-arginine by Neuronal NO-Synthase and Covalent Alteration of the Heme Prosthetic Group

2005 ◽  
Vol 18 (12) ◽  
pp. 1927-1933 ◽  
Author(s):  
Anthony J. Lee ◽  
Kathleen R. Noon ◽  
Suree Jianmongkol ◽  
Miranda Lau ◽  
Gary J. Jenkins ◽  
...  
Keyword(s):  
No Synthase ◽  
Prosthetic Group ◽  
Neuronal No Synthase ◽  
Heme Prosthetic Group

scholarly journals Neuronal Nitric Oxide Synthase and Ischemia-Induced Neurogenesis

2005 ◽  
Vol 25 (4) ◽  
pp. 485-492 ◽  
Author(s):  
Yunjuan Sun ◽  
Kunlin Jin ◽  
Jocelyn T Childs ◽  
Lin Xie ◽  
Xiao Ou Mao ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cerebral Ischemia ◽  
Infarct Size ◽  
Focal Cerebral Ischemia ◽  
Selective Inhibition ◽  
No Synthase ◽  
Adult Brain ◽  
Brdu Incorporation ◽  
Neuronal No Synthase ◽  
Synthase Inhibitor

Nitric oxide (NO) influences infarct size after focal cerebral ischemia and also regulates neurogenesis in the adult brain. These observations suggest that therapeutic approaches to stroke that target NO signaling may provide neuroprotection and also enhance brain repair through cell replacement. However, ischemic injury and neurogenesis are both affected differently depending on which isoform of NO synthase is the source of NO. In addition, ischemia itself stimulates neurogenesis, and ischemia-induced neurogenesis may be regulated differently than neurogenesis in nonischemic brain. To determine how neuronal NO synthase affects ischemia-induced neurogenesis, transient focal cerebral ischemia was produced in wild-type mice and in knockout mice lacking neuronal NO synthase, and BrdU incorporation and doublecortin immunoreactivity were measured in the principal neuroproliferative regions of the adult brain. Knockout of neuronal NO synthase reduced infarct size and increased both basal and ischemia-induced neurogenesis, suggesting that NO from this source is an inhibitory regulator of neurogenesis in the ischemic brain. 7-Nitroindazole, an NO synthase inhibitor that preferentially affects the neuronal isoform, also increased neurogenesis in rats when administered by the intracerebroventricular route. Selective inhibition of neuronal NO synthase may have the potential to both reduce infarct size and enhance neurogenesis in stroke.

scholarly journals Molecular Basis for Hyperactivity in Tryptophan 409 Mutants of Neuronal NO Synthase

2000 ◽  
Vol 275 (23) ◽  
pp. 17434-17439 ◽  
Author(s):  
Subrata Adak ◽  
Qian Wang ◽  
Dennis J. Stuehr
Keyword(s):  
Molecular Basis ◽  
No Synthase ◽  
Neuronal No Synthase

Resistance of PC12 cells against nitric oxide (NO)-induced toxicity in long-term culture: implication of neuronal NO synthase expression

2001 ◽  
Vol 309 (3) ◽  
pp. 169-172 ◽  
Author(s):  
Kohei Yuyama ◽  
Hideko Yamamoto ◽  
Kazuhiro Nakamura ◽  
Takeshi Kato ◽  
Ichiro Sora ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pc12 Cells ◽  
No Synthase ◽  
Neuronal No Synthase ◽  
Long Term Culture
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