Pilot evaluation of the population pharmacokinetics of bumetanide in term newborn infants with seizures

2015 ◽  
Vol 56 (3) ◽  
pp. 284-290 ◽  
Author(s):  
Vincent Jullien ◽  
Ronit M. Pressler ◽  
Geraldine Boylan ◽  
Mats Blennow ◽  
Neil Marlow ◽  
...  
Keyword(s):  
Population Pharmacokinetics ◽  
Newborn Infants ◽  
Term Newborn

scholarly journals Expired Tidal Volume and Respiratory Rate during Postnatal Stabilization of Term Newborn Infants Born by Cesarean Delivery

2020 ◽  
pp. 100063
Author(s):  
Susana Baixauli-Alacreu ◽  
Celia Padilla-Sánchez ◽  
David Hervás-Marín ◽  
Inmaculada Lara-Cantón ◽  
Alvaro Solaz-García ◽  
...  
Keyword(s):  
Tidal Volume ◽  
Respiratory Rate ◽  
Cesarean Delivery ◽  
Newborn Infants ◽  
Term Newborn

scholarly journals Delivery Room Management of Asphyxiated Term and Near-Term Infants

Neonatology ◽  
2021 ◽  
pp. 1-13
Author(s):  
Marlies Bruckner ◽  
Gianluca Lista ◽  
Ola D. Saugstad ◽  
Georg M. Schmölzer
Keyword(s):  
Preterm Infants ◽  
Newborn Infants ◽  
Neonatal Resuscitation ◽  
Birth Asphyxia ◽  
Delivery Room ◽  
Temperature Management ◽  
Term Infants ◽  
Term Newborn ◽  
Resuscitation Guidelines ◽  
Delivery Room Management

Approximately 800,000 newborns die annually due to birth asphyxia. The resuscitation of asphyxiated term newly born infants often occurs unexpected and is challenging for healthcare providers as it demands experience and knowledge in neonatal resuscitation. Current neonatal resuscitation guidelines often focus on resuscitation of extremely and/or very preterm infants; however, the recommendations for asphyxiated term newborn infants differ in some aspects to those for preterm infants (i.e., respiratory support, supplemental oxygen, and temperature management). Since the update of the neonatal resuscitation guidelines in 2015, several studies examining various resuscitation approaches to improve the outcome of asphyxiated infants have been published. In this review, we discuss current recommendations and recent findings and provide an overview of delivery room management of asphyxiated term newborn infants.

Breathing pattern and ventilation during oral feeding in term newborn infants

1985 ◽  
Vol 106 (5) ◽  
pp. 810-813 ◽  
Author(s):  
Oommen P. Mathew ◽  
Mark L. Clark ◽  
Maria L. Pronske ◽  
Hortencia G. Luna-Solarzano ◽  
Mary Dale Peterson
Keyword(s):  
Breathing Pattern ◽  
Newborn Infants ◽  
Oral Feeding ◽  
Term Newborn

Breast-Feeding and Hyperbilirubinemia in Full-Term Newborn Infants

PEDIATRICS ◽  
1985 ◽  
Vol 75 (3) ◽  
pp. 617-618
Author(s):  
CARLO CORCHIA ◽  
MARIA RUIU ◽  
MARCELLO ORZALESI
Keyword(s):  
Breast Feeding ◽  
Newborn Infants ◽  
Positive Association ◽  
Full Term ◽  
Neonatal Hyperbilirubinemia ◽  
Term Infants ◽  
Term Newborn ◽  
School Of Medicine

To the Editor.— Osborn et al1 have reported a positive association between breast-feeding and neonatal hyperbilirubinemia in full-term infants. To give further support to the findings of Osborn et al, we wish to report the results of two similar studies that have been completed in two different hospitals. The first study was carried out in the nursery of the Second School of Medicine of Naples.2 Rooming-in was practiced from 9 am to 12 pm, and during the day, breastfed babies were only offered a supplement of 5% dextrose in water when appropriate.

Prolonged half-life of caffeine in healthy term newborn infants

1981 ◽  
Vol 98 (4) ◽  
pp. 640-641 ◽  
Author(s):  
William D. Parsons ◽  
Allen H. Neims
Keyword(s):  
Half Life ◽  
Newborn Infants ◽  
Term Newborn

Pediatric Hazards of Drugs in Solutions Convenient for Administration to Adults

PEDIATRICS ◽  
1964 ◽  
Vol 33 (6) ◽  
pp. 999-999
Author(s):  
STANTON G. AXLINE ◽  
HAROLD J. SIMON
Keyword(s):  
Clinical Pharmacology ◽  
Body Weight ◽  
Newborn Infants ◽  
Full Term ◽  
Term Newborn

Studies on the clinical pharmacology of drugs in newborn infants have uncovered a problem of overdosage which may be more common than generally appreciated. Several medicaments are available only in a limited number of highly concentrated formulations. The requirements of premature and full-term newborn infants for very small total dosages necessitate very careful measurements of minute quantities of drug, and overdosage can readily occur. Specifically, Kanamycin is available in only two formulations for injection containing respectively 250 and 333 mg/ml. The dosage of this agent for newborn infants is approximately 8 mg/Kg of body weight 12 hourly.

HAZARDS OF LAUNDRY PRODUCTS USED IN THE NEWBORN NURSERY

PEDIATRICS ◽  
1971 ◽  
Vol 48 (6) ◽  
pp. 988-989
Author(s):  
Sumner J. Yaffe ◽  
Charles W. Bierman ◽  
Howard M. Cann ◽  
Arnold P. Gold ◽  
Frederic M. Kenney ◽  
...  
Keyword(s):  
Newborn Infants ◽  
Direct Proof ◽  
The United States ◽  
Maternity Hospital ◽  
Full Term ◽  
Accidental Poisoning ◽  
Severe Illness ◽  
Term Newborn ◽  
Health Agencies ◽  
Bacteriostatic Agent

Published reports and unpublished communications to the Committee on Drugs of the American Academy of Pediatrics indicate that substances potentially hazardous to the premature and full-term newborn infant continue to be used in the laundering of clothing, diapers, and bedding for hospital nurseries. In 1962 the Subcommittee on Accidental Poisoning called attention to occurrences of methemoglobinemia in premature and full-term newborn infants whose diapers were autoclaved after a final laundry rinse with the bacteriostatic agent, 3-4-4' trichlorocarbanilide (TCC).1 Subsequent reports in the pediatric literature confirmed and added to these "epidemics" of neonatal methemoglobinemia2-4 and suggested that aniline–a wellknown cause of methemoglobinemia5–resulting from the break-down of TCC during autoclaving, was absorbed from diapers and other nursery clothing through the skin of the infants. Although direct proof of the etiologic role of TCC is lacking, the association is of sufficient concern that the forthcoming Academy manual, Standards and Recommendations for Hospital Care of Newborn Infants, Second Edition, makes reference to the hazards of using TCC. Although a limited and informal survey of hospital nurseries in the United States and Canada indicates that most hospital laundry procedures have abandoned TCC in treating clothing and bed linens of newborn infants, sporadic instances of neonatal methemoglobinemia associated with exposure to this substance still come to the attention of local, state, and national health agencies, manufacturers, and the Committee on Drugs. In 1967, deaths and severe illness occurred in epidemic form in the newborn nursery of a small Midwestern maternity hospital.6 Investigation revealed that the sodium salt of pentachlorophenol (PCP)— which was present in the antimicrobial neutralizer product used in the final rinse of the laundry process for diapers, infant undershirts, and crib linens for the nursery–intoxicated babies by percutaneous absorption.7

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