scholarly journals Unusual Distribution Kinetics of Gadoxetate in Healthy Human Subjects Genotyped for OATP1B1: Application of Population Analysis and a Minimal Physiological‐Based Pharmacokinetic Model

2020 ◽  
Author(s):  
Michael Weiss ◽  
Werner Siegmund
Keyword(s):  
Pharmacokinetic Model ◽  
Human Subjects ◽  
Population Analysis ◽  
Healthy Human ◽  
Distribution Kinetics ◽  
Unusual Distribution ◽  
Healthy Human Subjects ◽  
Kinetics Of

Influence of usual intake of dietary caffeine on single-dose kinetics of theophylline in healthy human subjects

1993 ◽  
Vol 44 (3) ◽  
pp. 295-298 ◽  
Author(s):  
J. Sato ◽  
H. Nakata ◽  
E. Owada ◽  
T. Kikuta ◽  
M. Umetsu ◽  
...  
Keyword(s):  
Single Dose ◽  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects ◽  
Usual Intake ◽  
Kinetics Of

Chronic stress decreases circulating endocannabinoid 2-arachidonoylglycerol in healthy human subjects

2015 ◽  
Author(s):  
Buqing Yi ◽  
Igor Nichiporuk ◽  
Matthias Feuerecker ◽  
Gustav Schelling ◽  
Alexander Chouker
Keyword(s):  
Chronic Stress ◽  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects

scholarly journals Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 618
Author(s):  
Riley Larson ◽  
Courtney Nelson ◽  
Renee Korczak ◽  
Holly Willis ◽  
Jennifer Erickson ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Human Subjects ◽  
Area Under The Curve ◽  
Soluble Fiber ◽  
Healthy Human ◽  
Glucose Response ◽  
Blood Glucose Response ◽  
Acacia Gum ◽  
Fiber Treatment ◽  
Healthy Human Subjects

Acacia gum (AG) is a non-viscous soluble fiber that is easily incorporated into beverages and foods. To determine its physiological effects in healthy human subjects, we fed 0, 20, and 40 g of acacia gum in orange juice along with a bagel and cream cheese after a 12 h fast and compared satiety, glycemic response, gastrointestinal tolerance, and food intake among treatments. Subjects (n = 48) reported less hunger and greater fullness at 15 min (p = 0.019 and 0.003, respectively) and 240 min (p = 0.036 and 0.05, respectively) after breakfast with the 40 g fiber treatment. They also reported being more satisfied at 15 min (p = 0.011) and less hungry with the 40 g fiber treatment at 30 min (p = 0.012). Subjects reported more bloating, flatulence, and GI rumbling on the 40 g fiber treatment compared to control, although values for GI tolerance were all low with AG treatment. No significant differences were found in area under the curve (AUC) or change from baseline for blood glucose response, although actual blood glucose with 20 g fiber at 30 min was significantly less than control. Individuals varied greatly in their postprandial glucose response to all treatments. AG improves satiety response and may lower peak glucose response at certain timepoints, and it is well tolerated in healthy human subjects. AG can be added to beverages and foods in doses that can help meet fiber recommendations.

Diaphragmatic Fatigue after Exercise in Healthy Human Subjects

1993 ◽  
Vol 148 (6_pt_1) ◽  
pp. 1571-1575 ◽  
Author(s):  
M. Jeffery Mador ◽  
Ulysses J. Magalang ◽  
Angel Rodis ◽  
Thomas J. Kufel
Keyword(s):  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects ◽  
Diaphragmatic Fatigue

Capsaicin and glucose absorption and utilization in healthy human subjects

2006 ◽  
Vol 534 (1-3) ◽  
pp. 280-283 ◽  
Author(s):  
András Dömötör ◽  
János Szolcsányi ◽  
Gyula Mózsik
Keyword(s):  
Human Subjects ◽  
Glucose Absorption ◽  
Healthy Human ◽  
Healthy Human Subjects
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