Dose Optimization in Kidney Disease: Opportunities for PBPK Modeling and Simulation

Yoko Franchetti; Thomas D. Nolin

doi:10.1002/jcph.1741

Dose Optimization in Kidney Disease: Opportunities for PBPK Modeling and Simulation

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1741 ◽

2020 ◽

Vol 60 (S1) ◽

Cited By ~ 1

Author(s):

Yoko Franchetti ◽

Thomas D. Nolin

Keyword(s):

Kidney Disease ◽

Modeling And Simulation ◽

Pbpk Modeling ◽

Dose Optimization

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Dose optimization of moxifloxacin and linezolid against tuberculosis using mathematical modeling and simulation

International Journal of Antimicrobial Agents ◽

10.1016/j.ijantimicag.2018.10.012 ◽

2019 ◽

Vol 53 (3) ◽

pp. 275-283 ◽

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George L. Drusano ◽

David L. Brown ◽

Michael S. Maynard ◽

Sherwin K.B. Sy ◽

...

Keyword(s):

Mathematical Modeling ◽

Modeling And Simulation ◽

Dose Optimization

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Keyword(s):

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Modeling And Simulation ◽

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Pbpk Modeling

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Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification

Drug Metabolism and Disposition ◽

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2015 ◽

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Jingjing Yu ◽

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Nina Isoherranen

Keyword(s):

Systematic Review ◽

Modeling And Simulation ◽

Model Verification ◽

Pbpk Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

The Journal of Clinical Pharmacology ◽

10.1177/0091270011415528 ◽

2012 ◽

Vol 52 (S1) ◽

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Author(s):

Ping Zhao ◽

Manuela de L. T. Vieira ◽

Joseph A. Grillo ◽

Pengfei Song ◽

Ta‐Chen Wu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation

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Vol 38 (6) ◽

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Yoshihiko Tagawa ◽

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Yoshiyuki Furukawa ◽

...

Keyword(s):

Modeling And Simulation ◽

Pbpk Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Population pharmacokinetic modeling and simulation of amprenavir following fosamprenavir/ritonavir administration for dose optimization in HIV infected pediatric patients

The Journal of Clinical Pharmacology ◽

10.1002/jcph.205 ◽

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Leonid Gibiansky ◽

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Keyword(s):

Modeling And Simulation ◽

Pediatric Patients ◽

Pharmacokinetic Modeling ◽

Dose Optimization ◽

Population Pharmacokinetic ◽

Population Pharmacokinetic Modeling ◽

Pharmacokinetic Modeling And Simulation

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Physiologically based pharmacokinetic (PBPK) modeling and simulation in neonatal drug development: how clinicians can contribute

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pp. 25-34 ◽

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Pieter De Cock ◽

An Vermeulen ◽

Karel Allegaert

Keyword(s):

Drug Development ◽

Modeling And Simulation ◽

Pbpk Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Report from the EMA workshop on qualification and reporting of physiologically based pharmacokinetic (PBPK) modeling and simulation

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pp. 71-72 ◽

Cited By ~ 11

Author(s):

P Zhao

Keyword(s):

Modeling And Simulation ◽

Pbpk Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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P212 - PBPK modeling and simulation of morphine in virtual neonates generated using actual patient information

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2020.04.213 ◽

2020 ◽

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pp. S86-S87

Author(s):

Chie Emoto ◽

David Hahn ◽

Joshua Euteneuer ◽

Tomoyuki Mizuno ◽

Alexander Vinks ◽

...

Keyword(s):

Modeling And Simulation ◽

Patient Information ◽

Pbpk Modeling ◽

Actual Patient

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Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2106 ◽

2017 ◽

Vol 38 (9) ◽

pp. 543-552

Author(s):

Akihiko Goto ◽

Yoshihiko Tagawa ◽

Yuu Moriya ◽

Sho Sato ◽

Masami Yamamoto ◽

...

Keyword(s):

Body Composition ◽

Modeling And Simulation ◽

Pbpk Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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