Impact of the Selective Orexin‐1 Receptor Antagonist ACT‐539313 on the Pharmacokinetics of the CYP3A Probe Drug Midazolam in Healthy Male Subjects

2020 ◽  
Vol 60 (7) ◽  
pp. 931-941 ◽  
Author(s):  
Benjamin Berger ◽  
Priska Kaufmann ◽  
Annelize Koch ◽  
Jasper Dingemanse
Keyword(s):  
Receptor Antagonist ◽  
Healthy Male ◽  
Probe Drug ◽  
Male Subjects

scholarly journals P10 The Effect Of Naltrexone, An Opioid Receptor Antagonist, On Capsaicin Evoked Cough, In Healthy Male Subjects

Thorax ◽  
2014 ◽  
Vol 69 (Suppl 2) ◽  
pp. A81-A82
Author(s):  
I. Satia ◽  
K. Holt ◽  
E. Hilton ◽  
A. Woodcock ◽  
J. Smith
Keyword(s):  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Healthy Male ◽  
Opioid Receptor Antagonist ◽  
Male Subjects

Dose-dependent effects of the CRF1 receptor antagonist R317573 on regional brain activity in healthy male subjects

2009 ◽  
Vol 208 (1) ◽  
pp. 109-119 ◽  
Author(s):  
Mark E. Schmidt ◽  
Randolph D. Andrews ◽  
Peter van der Ark ◽  
Terry Brown ◽  
Erik Mannaert ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Brain Activity ◽  
Healthy Male ◽  
Crf1 Receptor ◽  
Regional Brain ◽  
Crf1 Receptor Antagonist ◽  
Regional Brain Activity ◽  
Dose Dependent ◽  
Male Subjects

P.1.c.032 Interaction study between almorexant, a dual orexin receptor antagonist, and desipramine in healthy male subjects

2010 ◽  
Vol 20 ◽  
pp. S253
Author(s):  
H. Cruz ◽  
P. Hoever ◽  
J. Hay ◽  
F. Alessi ◽  
J. Dingemanse ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Interaction Study ◽  
Healthy Male ◽  
Male Subjects

Food Effect and Biocomparison of Two Formulations of the Dual Orexin Receptor Antagonist Almorexant in Healthy Male Subjects

2011 ◽  
Vol 51 (7) ◽  
pp. 1116-1121 ◽  
Author(s):  
Matthias Hoch ◽  
Petra Hoever ◽  
Manuel Haschke ◽  
Stephan Krähenbühl ◽  
Jasper Dingemanse
Keyword(s):  
Receptor Antagonist ◽  
Food Effect ◽  
Healthy Male ◽  
Male Subjects

884: Phase I, Double-Blind, Placebo-Controlled Study in Healthy Male Subjects to Investigate the Safety, Tolerability, and Pharmacokinetics of DA-8159

2004 ◽  
Vol 171 (4S) ◽  
pp. 234-234 ◽  
Author(s):  
Harin Padma-Nathan ◽  
Jae Seung Pacik ◽  
Byoung Ok Ahn ◽  
Kyung Koo Kang ◽  
Mi Young Bahng ◽  
...  
Keyword(s):  
Phase I ◽  
Controlled Study ◽  
Healthy Male ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Male Subjects
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