ROS–NLRP3 signaling pathway induces sterile inflammation after thulium laser resection of the prostate

2022 ◽  
Author(s):  
Xing‐Jie Wang ◽  
Xiao‐Qing Ni ◽  
Sheng Zhao ◽  
Rui‐Zhe Zhao ◽  
Xiao‐Hai Wang ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Sterile Inflammation ◽  
Thulium Laser ◽  
Laser Resection

Comparison of Thulium Laser Resection of Bladder Tumors and Conventional Transurethral Resection of Bladder Tumors for Non-Muscle-Invasive Bladder Cancer

2021 ◽  
pp. 1-6
Author(s):  
Zheng Liu ◽  
Yucong Zhang ◽  
Guoliang Sun ◽  
Wei Ouyang ◽  
Shen Wang ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Transurethral Resection ◽  
Invasive Bladder Cancer ◽  
Perioperative Outcomes ◽  
Thulium Laser ◽  
Bladder Tumors ◽  
Muscle Invasive Bladder Cancer ◽  
Laser Resection ◽  
Baseline Characteristics ◽  
Muscle Invasive

<b><i>Introduction:</i></b> The thulium laser resection of bladder tumors (TmLRBT) was increasingly used in the treatment of non-muscle-invasive bladder cancer (NMIBC) recently, and here we report the relevant outcomes of our institution to evaluate its efficacy and safety. <b><i>Methods:</i></b> We retrospectively collected the data of NMIBC patients who underwent either TmLRBT or transurethral resection of bladder tumor (TURBT). The baseline characteristics and perioperative outcomes were compared in these 2 groups. <b><i>Results:</i></b> The TmLRBT had a higher rate of detrusor identification than TURBT (97.4 vs. 87.6%, <i>p</i> = 0.001). After screening, 134 patients who underwent TmLRBT and 152 patients who received TURBT were enrolled in the analysis, and their baseline characteristics were similar. During the TURBT, 24 (15.8%) obturator nerve reflexes and 9 (5.9%) bladder perforations occurred, while none happened during the TmLRBT. After surgery, TmLRBT patients had fewer postoperative gross hematuria (38.1 vs. 96.7%, <i>p</i> &#x3c; 0.001) and postoperative irrigation (27.6 vs. 92.7%, <i>p</i> &#x3c; 0.001), and its irrigation duration was significantly shorter (2.3 vs. 3.3 day, <i>p</i> &#x3c; 0.001). During the follow-up, no significant difference in the recurrence rate was detected (<i>p</i> = 0.315). <b><i>Conclusions:</i></b> TmLRBT is a safer technique than conventional TURBT in the treatment of NMIBC, and it could offer better specimens for pathologic assessment while the cancer control was not compromised.

Two-micrometer thulium laser resection of the prostate-tangerine technique for patients with acute urinary retention

2013 ◽  
Vol 29 (3) ◽  
pp. 1093-1098 ◽  
Author(s):  
Jian Zhuo ◽  
Hai-Bin Wei ◽  
Fu-Jun Zhao ◽  
Feng Sun ◽  
Bang-Min Han ◽  
...  
Keyword(s):  
Urinary Retention ◽  
Acute Urinary Retention ◽  
Thulium Laser ◽  
Laser Resection

V43 En bloc thulium laser resection of bladder tumours: Indications, surgical tips, and 3-yr oncologic outcomes

2016 ◽  
Vol 15 (3) ◽  
pp. eV43
Author(s):  
G. Simone ◽  
A. Giacobbe ◽  
R. Papalia ◽  
D. Collura ◽  
R. Rosso ◽  
...  
Keyword(s):  
Oncologic Outcomes ◽  
Thulium Laser ◽  
En Bloc ◽  
Laser Resection ◽  
Bladder Tumours

scholarly journals Thulium Laser Resection of Bladder Tumors vs. Conventional Transurethral Resection of Bladder Tumors for Intermediate and High Risk Non-Muscle-Invasive Bladder Cancer Followed by Intravesical BCG Immunotherapy

2021 ◽  
Vol 8 ◽  
Author(s):  
Zheng Liu ◽  
Gongwei Long ◽  
Yucong Zhang ◽  
Guoliang Sun ◽  
Wei Ouyang ◽  
...  
Keyword(s):  
Transurethral Resection ◽  
Cox Regression ◽  
Recurrence Risk ◽  
Perioperative Outcomes ◽  
Thulium Laser ◽  
Bladder Tumors ◽  
Laser Resection ◽  
Bcg Immunotherapy ◽  
Intravesical Bcg ◽  
Muscle Invasive

Background: Thulium laser resection of bladder tumors (TmLRBT) is recently considered as a common treatment option for non-muscle-invasive bladder cancers (NMIBC), but whether it is superior to Transurethral resection of bladder tumors (TURBT) are still undetermined.Materials and Methods: We retrospectively screened our institution database to identify patients who were treated by conventional TURBT or TmLRBT for NMIBC and followed by intravesical bacillus Calmette-Guérin (BCG) immunotherapy. The preoperative characteristics, perioperative outcomes, and recurrence-free survival were compared to assess the safety and efficacy of the two procedures.Results: Eventually, 90 patients who underwent TmLRBT (n = 37) or TURBT (n = 53) followed by intravesical BCG immunotherapy were included. Two groups were similar in baseline characteristics except for the smaller tumor size of the TmLRBT group(1.7 cm vs. 2.2 cm; P = 0.036). Obturator nerve reflex occurred in eight patients in the TURBT group and 3 of them suffered from bladder perforation while none happened in the TmLRBT group. The TmLRBT also had a shorter irrigation duration. In the multivariate Cox regression, the TmLRBT was related to less recurrence risk (HR: 0.268; 95% CI, 0.095–0.759; P = 0.013).Conclusion: Our results suggested that TmLRBT is safer than conventional TURBT with fewer perioperative complications, and it offers better cancer control, therefore might be a superior option for NMIBC patients with intermediate and high recurrence risk.

Vl345: The Thulium-Laser Resection of the Prostate

2005 ◽  
Vol 173 (4S) ◽  
pp. 365-366 ◽  
Author(s):  
Robert Götschl ◽  
Nikolaus T. Schmeller
Keyword(s):  
Thulium Laser ◽  
Laser Resection

1777 EN BLOC THULIUM LASER RESECTION OF BLADDER CANCER: POSSIBLE FUTURE STANDARD?

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
GIOVANNI MUTO ◽  
LEONARDO D'URSO ◽  
EMANUELE CASTELLI ◽  
DEVIS COLLURA ◽  
ALESSANDRO GIACOBBE
Keyword(s):  
Bladder Cancer ◽  
Thulium Laser ◽  
En Bloc ◽  
Laser Resection
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