Islet amyloid toxicity: From genesis to counteracting mechanisms

2021 ◽  
Author(s):  
Carine Marmentini ◽  
Renato C. S. Branco ◽  
Antonio C. Boschero ◽  
Mirian A. Kurauti
Keyword(s):  
Islet Amyloid ◽  
Amyloid Toxicity

Evidence for Necroptosis as a Mechanism of Islet Amyloid–Induced Beta-Cell Death

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 82-OR
Author(s):  
ANDREW T. TEMPLIN ◽  
MEGHAN F. HOGAN ◽  
NATHALIE ESSER ◽  
SAKENEH ZRAIKA ◽  
REBECCA L. HULL ◽  
...  
Keyword(s):  
Cell Death ◽  
Beta Cell ◽  
Islet Amyloid ◽  
Beta Cell Death

2132-P: Islet Amyloid Deposition Is Cytotoxic to Islet Endothelial Cells

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2132-P
Author(s):  
JOSEPH J. CASTILLO ◽  
MEGHAN F. HOGAN ◽  
ALFRED APLIN ◽  
DARYL J. HACKNEY ◽  
REBECCA L. HULL
Keyword(s):  
Endothelial Cells ◽  
Amyloid Deposition ◽  
Islet Amyloid

2040-P: Chronic Activation of CREB by Islet Amyloid Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2040-P
Author(s):  
MEGHAN F. HOGAN ◽  
NATHALIE ESSER ◽  
ANDREW T. TEMPLIN ◽  
JOSEPH J. CASTILLO ◽  
SAKENEH ZRAIKA ◽  
...  
Keyword(s):  
Protein Expression ◽  
Regulatory Protein ◽  
Steroidogenic Acute Regulatory Protein ◽  
Islet Amyloid ◽  
Chronic Activation ◽  
Steroidogenic Acute Regulatory

Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans

Diabetes ◽  
1994 ◽  
Vol 43 (5) ◽  
pp. 640-644 ◽  
Author(s):  
E. J. de Koning ◽  
J. W. Hoppener ◽  
J. S. Verbeek ◽  
C. Oosterwijk ◽  
K. L. van Hulst ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Lack of islet amyloid polypeptide regulation of insulin biosynthesis or secretion in normal rat islets

Diabetes ◽  
1990 ◽  
Vol 39 (7) ◽  
pp. 871-874 ◽  
Author(s):  
S. Nagamatsu ◽  
R. J. Carroll ◽  
G. M. Grodsky ◽  
D. F. Steiner
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Insulin Biosynthesis ◽  
Islet Amyloid ◽  
Rat Islets ◽  
Normal Rat

Is islet amyloid polypeptide a significant factor in pathogenesis or pathophysiology of diabetes?

Diabetes ◽  
1991 ◽  
Vol 40 (3) ◽  
pp. 305-309 ◽  
Author(s):  
D. F. Steiner ◽  
S. Ohagi ◽  
S. Nagamatsu ◽  
G. I. Bell ◽  
M. Nishi
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Islet Amyloid

Islet amyloid polypeptide response to glucose, insulin, and somatostatin analogue administration

Diabetes ◽  
1990 ◽  
Vol 39 (5) ◽  
pp. 639-642 ◽  
Author(s):  
T. Mitsukawa ◽  
J. Takemura ◽  
J. Asai ◽  
M. Nakazato ◽  
K. Kangawa ◽  
...  
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Somatostatin Analogue ◽  
Islet Amyloid

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells

Diabetes ◽  
1990 ◽  
Vol 39 (5) ◽  
pp. 634-638 ◽  
Author(s):  
S. E. Kahn ◽  
D. A. D'Alessio ◽  
M. W. Schwartz ◽  
W. Y. Fujimoto ◽  
J. W. Ensinck ◽  
...  
Keyword(s):  
Beta Cells ◽  
Islet Amyloid Polypeptide ◽  
Islet Amyloid
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