Regulation of autophagy by protein methylation and acetylation in cancer

2021 ◽  
Author(s):  
Minsol Jeon ◽  
Jisu Park ◽  
Eunbi Yang ◽  
Hee‐ji Baek ◽  
Hyunkyung Kim
Keyword(s):  
Protein Methylation

Review of Progress in Predicting Protein Methylation Sites

2019 ◽  
Vol 23 (15) ◽  
pp. 1663-1670 ◽  
Author(s):  
Chunyan Ao ◽  
Shunshan Jin ◽  
Yuan Lin ◽  
Quan Zou
Keyword(s):  
Gene Expression ◽  
Signal Transduction ◽  
Transcriptional Activity ◽  
Regulation Of Gene Expression ◽  
Protein Methylation ◽  
Biological Processes ◽  
Post Translational Modification ◽  
Regulatory Enzymes ◽  
Lysine Residues ◽  
Arginine Residues

Protein methylation is an important and reversible post-translational modification that regulates many biological processes in cells. It occurs mainly on lysine and arginine residues and involves many important biological processes, including transcriptional activity, signal transduction, and the regulation of gene expression. Protein methylation and its regulatory enzymes are related to a variety of human diseases, so improved identification of methylation sites is useful for designing drugs for a variety of related diseases. In this review, we systematically summarize and analyze the tools used for the prediction of protein methylation sites on arginine and lysine residues over the last decade.

scholarly journals Identifying the recognition unit for G protein methylation

1991 ◽  
Vol 266 (17) ◽  
pp. 10719-10722
Author(s):  
E.W. Tan ◽  
D. Pérez-Sala ◽  
F.J. Cañada ◽  
R.R. Rando
Keyword(s):  
G Protein ◽  
Protein Methylation

scholarly journals Sex-Specific Effects of Dietary Methionine Restriction on the Intestinal Microbiome

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 781 ◽  
Author(s):  
Katherine F. Wallis ◽  
Stepan B. Melnyk ◽  
Isabelle R. Miousse
Keyword(s):  
Body Weight ◽  
Animal Models ◽  
Intestinal Microbiota ◽  
Methylation Status ◽  
Intestinal Microbiome ◽  
Protein Methylation ◽  
Restricted Diet ◽  
Male And Female ◽  
Specific Effects ◽  
Methionine Restriction

Dietary methionine restriction is associated with improved health outcomes and an increase in lifespan in animal models. We have previously shown that an increase in dietary methionine induces alteration in the intestinal microbiome. The composition of the intestinal microbiota is a determinant of health and we, therefore, hypothesized that dietary methionine restriction would also induce changes in the murine microbiome. After one month on a methionine-restricted diet, five-month-old male and female C57BL/6 mice had decreased levels of serum methionine, without changes in body weight. We identified a decrease in the hepatic methylation status of animals fed a methionine-restricted diet compared to controls. This decrease was not associated with changes in DNA or protein methylation in the liver. In males, we saw an increase in families Bacteroidaceae and Verrucoccaceae (mostly A. mucinophila) and a decrease in Rumminococcaceae in animals fed a methionine-restricted diet compared to controls. In females, Bacteroidales family S24-7 was increased two-fold, while families Bacteroidaceae, Verrucoccaceae, Rumminococcaceae, and Rikenellaceae were decreased compared to controls. In summary, feeding a methionine-restricted diet for one month was associated with significant and sex-specific changes in the intestinal microbiome.

scholarly journals Protein methylation inCaldariella acidophila, an extreme thermo-acidophilic archaebacterium

FEBS Letters ◽  
1981 ◽  
Vol 124 (1) ◽  
pp. 62-66 ◽  
Author(s):  
Patrizia Galletti ◽  
Mario De Rosa ◽  
Agata Gambacorta ◽  
Caterina Manna ◽  
Rosario Festinese ◽  
...  
Keyword(s):  
Protein Methylation

scholarly journals Bioorthogonal Profiling of Protein Methylation Using Azido Derivative of S-Adenosyl-l-methionine

2012 ◽  
Vol 134 (13) ◽  
pp. 5909-5915 ◽  
Author(s):  
Kabirul Islam ◽  
Ian Bothwell ◽  
Yuling Chen ◽  
Caitlin Sengelaub ◽  
Rui Wang ◽  
...  
Keyword(s):  
Protein Methylation

Genetics of ribosomal protein methylation in Escherichia coli

1977 ◽  
Vol 154 (2) ◽  
pp. 175-180 ◽  
Author(s):  
Jacques Lhoest ◽  
Charles Colson
Keyword(s):  
Escherichia Coli ◽  
Ribosomal Protein ◽  
Protein Methylation

scholarly journals Modulating the Modulator: Regulation of Protein Methylation by Nitric Oxide

2017 ◽  
Vol 67 (4) ◽  
pp. 535-537 ◽  
Author(s):  
Lucas Frungillo ◽  
Steven H. Spoel
Keyword(s):  
Nitric Oxide ◽  
Protein Methylation
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