Harnessing the targeting potential of differential radiobiological effects of photon versus particle radiation for cancer treatment

2020 ◽  
Vol 236 (3) ◽  
pp. 1695-1711
Author(s):  
Jinhua Zhang ◽  
Jing Si ◽  
Lu Gan ◽  
Rong Zhou ◽  
Menghuan Guo ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Particle Radiation ◽  
Radiobiological Effects ◽  
Versus Particle

scholarly journals The Role of Low Energy Electrons in Radiobiology and Cancer Treatment

2021 ◽  
Author(s):  
Sasan Esmaili ◽  
Farzaneh Allaveisi
Keyword(s):  
Cancer Treatment ◽  
Anticancer Agents ◽  
High Energy ◽  
Low Energy ◽  
New Drugs ◽  
Particle Radiation ◽  
Energy Radiation ◽  
Regulatory Pathways ◽  
High Energy Electrons ◽  
Low Energy Electrons

Low energy radiation can be produced by all types of high energy radiation. Studies of low energy particle radiation help us to understand the chemistry induced by high energy radiations. Low energy electrons are capable of chemical selectivity in contrast to high energy electrons due to the large number of open dissociative channels in the former case and their resonant nature. Among different types of radiation, low energy electrons have a higher cross-section to DNA damage and they have an important role in the synergistic effect between radiation and chemotherapy anticancer agents in cancer treatment. Analysis of these combined records helps assign function of cells, identify metabolic and regulatory pathways and suggest targets for diagnostics and therapeutics identify animal models to develop new drugs, among other goals of biomedical interest.

1077: A Novel Apoptosis-Inducing Gene and its Application in Prostate Cancer Treatment

2004 ◽  
Vol 171 (4S) ◽  
pp. 284-284
Author(s):  
Yi Lu ◽  
Jun Zhang ◽  
Ben Beheshti ◽  
Ximing J. Yang ◽  
Syamal K. Bhattacharya ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Treatment ◽  
Prostate Cancer Treatment

Molecular Mechanism of Apoptosis Induction by Resveratrol, a Natural Cancer Chemopreventive Agent

2008 ◽  
Vol 78 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Fan ◽  
Jiang ◽  
Zhang ◽  
Bai
Keyword(s):  
Cancer Treatment ◽  
Molecular Mechanism ◽  
Apoptosis Induction ◽  
Protective Agents ◽  
Chemopreventive Agent ◽  
Naturally Occurring ◽  
Apoptosis Pathways ◽  
Present Understanding

In efforts to identify naturally occurring compounds that act as protective agents, resveratrol, a phytoalexin existing in wine, has attracted much interest because of its diverse pharmacological characteristics. Considering that apoptosis induction is the most potent defense approach for cancer treatment, we have tried to summarize our present understanding of apoptosis induction by resveratrol based on the two major apoptosis pathways.

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